Academic Articles & Research Papers

The Reliability and Sensitivity of Change of Direction Deficit and Its Association with Linear Sprint Speed in Prepubertal Male Soccer Players

Background: This study aimed to examine the reliability and sensitivity of a change of direction deficit (CoDD) and to establish its relationship with linear sprint speed. Methods: In total, 89 prepubertal male soccer players participated i...

Assessment of Quality of Life and Social Correlates among Drug Sensitive and Multidrug-resistant Tuberculosis Patients

Background: Tuberculosis (TB) has significant health, social, psychological, and economic impacts on patients. This study aimed to assess and compare quality of life (QOL) among multidrug-resistant (MDR) TB patients and drug-sensitive TB pa...

The effect of 8 weeks of whole body vibration training on static balance and explosive strength of lower limbs in physical education students

Background: It has been shown that whole body vibration training has an effect on strength and balance in athletes of various sports.Objective: The purpose of the study was to examine the effect of 8 weeks of Whole Body Vibration (WBV) trai...

METHOD OF CONVERSATION IN PSYCHODIAGNOSTICS BY PROJECTIVE METHODS IN WORKING WITH STUDENTS OF NAUTICAL SPECIALTIES

Is health-related quality of life the same for elderly polish migrants, Turkish migrants and German natives? Testing the reliability and construct validity of the Sf-36 health survey in a cross-cultural comparison

Objective: The Sf-36 is the most widely used instrument to measure health-related quality of life (HRQoL) with the most convincing evidence of both internal consistency and test–retest reliability. In addition, it is appropriate for use amo...

Fedratinib reveals chemotherapeutic potential in esophageal squamous cell cancer

BackgroundDrug repurposing has emerged as a promising approach for discovering novel anticancer therapeutics. In this study, we systematically investigated the antitumor potential of fedratinib, a JAK2 inhibitor approved for myelofibrosis, ...

Plexiform Neurofibroma Treated with Pharmacopuncture

Objectives: The purpose of this study is to report a case of a plexiform neurofibroma (PNF) in the pelvic region treated with sweet bee venom (SBV) and mountain ginseng pharmacopuncture (MGP). Methods: A 16-year-old girl was diagnosed as h...

The Utilization of Plant-Material-Loaded Vesicular Drug Delivery Systems in the Management of Pulmonary Diseases

Medicinal plants have been utilized to treat a variety of conditions on account of the bioactive properties that they contain. Most bioactive constituents from plants are of limited effectiveness, due to poor solubility, limited permeabilit...

Efficacy, safety, and quality of life 4 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A in the phase 3 GENEr8-1 trial

Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...

Formulation, development and evaluation of buccoadhesive drug delivery system of risperidone

Aim and Objective: The study aimed to manufacture Bucco-adhesive tablets of Risperidone and characterize the effectiveness of the drug by incorporating it into the mucoadhesive drug delivery system. The sustained release tablets reduced the...

The Association of Parent-Child Communication With Internet Addiction in Left-Behind Children in China: A Cross-Sectional Study

Objective: Internet addiction has emerged as a growing concern worldwide. This study aimed to compare the prevalence of Internet addiction between left-behind children (LBC) and non-left-behind children (non-LBC), and explore the role of pa...

Lactobacillus brevis 23017 Relieves Mercury Toxicity in the Colon by Modulation of Oxidative Stress and Inflammation Through the Interplay of MAPK and NF-κB Signaling Cascades

Aims:Lactobacillus strains have protective effects against heavy metals while relieving oxidative stress and modulating the immune response. Mechanisms that ameliorate heavy metal toxicity and the relationship between probiotics and gut bar...

Fumaric acid regulates morphine tolerance in bone cancer pain through spinal MrgC receptor modulation

Background: Bone cancer pain (BCP) represents a debilitating complication that profoundly impacts patient quality of life and predisposes to psychological comorbidities, including depression and anxiety. Objectives: To investigate the effec...

Enteric Coating Enhances the Biopharmaceutical Performance of a Silica–Lipid Formulation of Abiraterone Acetate

Background/Objectives: Lipid-based formulations are widely used to enhance the oral bioavailability of poorly water-soluble drugs. However, for weakly basic drugs with higher solubility under acidic conditions, precipitation and recrystalli...

Comparison of Vitamin B1 (Thiamin hydrochloride) Level in Brown Rice (Oryza nivara S.D.Sharma & Shastry) and Cooked Brown Rice by Alkalimetry Methods

Brown rice (Oryza nivara S.D.Sharma & Shastry) is a rice variety that belongs to the Graminae family. Brown rice contains vitamins A, B, C, Zn and B complex. Vitamin B1 is one type of vitamin that is not stable. Its stability is influenced ...

Modulation Instability and Abundant Exact Solitons to the Fractional Mathematical Physics Model Through Two Distinct Methods

The paper consists of various types of wave solutions for the truncated M-fractional Bateman–Burgers equation, a significant mathematical physics equation. This model describes the nonlinear waves and solitons in different physical fields s...

Molecularly Imprinted Polymers for Biosensing: From Synthetic Recognition to Integrated Biointerfaces

Molecularly imprinted polymers (MIPs) are synthetic receptors with cavities shaped around a template, combining antibody-like selectivity with chemical, thermal, and mechanical robustness; low cost; and reusability. This Review examines rec...

Mechanism analysis of mechanical extraction of Pleioblastus amarus fibers by saturated steam pretreatment

Abstract Currently, bamboo fibers (BFs) are commonly processed through alkali boiling softening pretreatment, which generates wastewater that poses environmental pollution risks. This process is also complex and requires significant human a...

Effect of Phacoemulsification on Macular Thickness and Volume in Diabetic Patients without Retinopathy

Introduction: This study aimed to investigate the effect of phacoemulsification on macular thickness and volume in diabetic patients without retinopathy using optical coherence tomography (OCT).Methods: This prospective study included 37 di...

Correction of Postoperative Anemia in Patients undergoing Mitral Valve Replacement through Blood Saving Technology

The aim. To investigate anemia of chronic disease (ACD) in patients with mitral valvular disease, to provide preoperative correction in these patients and to determine the level of postoperative anemia after mitral valve replacement (MVR) t...