Reset
Showing 20 of 983 academic articles

Metabolomic Profile Alterations Associated with the SLC16A11 Risk Haplotype Following a Lifestyle Intervention in People With Prediabetes

Magdalena Sevilla-González, Maria Fernanda Garibay-Gutiérrez, Arsenio Vargas-Vázquez, Andrea Celeste Medina-García et al. • Current Developments in Nutrition (2024)

Background: A risk haplotype in SLC16A11 characterized by alterations in fatty acid metabolism emerged as a genetic risk factor associated with increased susceptibility to type 2 diabetes (T2D) in Mexican population. Its role on treatment r...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.cdnut.2024.104444

Genome-wide association studies for the identification of cattle susceptible and resilient to paratuberculosis

Marta Alonso-Hearn, Gerard Badia-Bringué, Maria Canive • Frontiers in Veterinary Science (2022)

Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease or paratuberculosis (PTB), with important animal health and economic implications. There are no therapeutic strategies to control this disease, and vaccination with in...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2022.935133

Interacting roles of gut microbiota and T cells in the development of autoimmune hepatitis

Qingwei Wu, Zhifa Ge, Chengyu Lv, Qifeng He • Frontiers in Immunology (2025)

Autoimmune hepatitis (AIH) is a progressive liver inflammatory disease mediated by an autoimmune response, with an increasing incidence rate. In severe cases, AIH will rapidly progress to liver cirrhosis and liver failure and even lead to d...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2025.1584001

Genetic Markers of Adaptation of <named-content content-type="genus-species">Plasmodium falciparum</named-content> to Transmission by American Vectors Identified in the Genomes of Parasites from Haiti and South America

Massimiliano S. Tagliamonte, Charles A. Yowell, Maha A. Elbadry, Jacques Boncy et al. • mSphere (2020)

ABSTRACT The malaria parasite, Plasmodium falciparum, was introduced into Hispaniola and other regions of the Americas through the slave trade spanning the 16th through the 19th centuries. During this period, more than 12 million Africans w...

DOAJ Open Access (DOAJ) DOI: 10.1128/mSphere.00937-20

Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target

Xiaofeng Duan, Stephen Iwanowycz, Soo Ngoi, Megan Hill et al. • Frontiers in Oncology (2021)

During tumor development and progression, intrinsic and extrinsic factors trigger endoplasmic reticulum (ER) stress and the unfolded protein response, resulting in the increased expression of molecular chaperones to cope with the stress and...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2021.629846

Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation

Oliver H. Bell, David A. Copland, Amy Ward, Lindsay B. Nicholson et al. • Frontiers in Immunology (2020)

Background: Whether retinal microglia can maintain or restore immune homeostasis during and after inflammation is unclear. We performed single-eye mRNA-sequencing on microglia at different timepoints following a single inflammatory stimulus...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2019.03033

Recuperação Completa de Doente com Carcinoma da Próstata Estádio IV Durante a Pandemia COVID-19

Gil Falcão, Cabrita Carneiro, Luís Campos Pinheiro • Gazeta Médica (2020)

A doença causada pelo coronavírus (COVID-19), inicialmente descrita em Wuhan, China, foi recentemente declarada pela Organização Mundial da Saúde (OMS) como uma pandemia global. A idade avançada e a presença de comorbilidades, característic...

DOAJ Open Access (DOAJ) DOI: 10.29315/gm.v7i2.328

Technology-Supported Behavior Change—Applying Design Thinking to mHealth Application Development

Ramona Schweitzer, Stephan Schlögl, Marco Schweitzer • European Journal of Investigation in Health, Psychology and Education (2024)

Non-communicable diseases are the leading cause of global deaths. The risk of their development and progression is increased by modifiable behavioral risk factors. Yet, despite the known benefits of primary and secondary prevention, people ...

DOAJ Open Access (DOAJ) DOI: 10.3390/ejihpe14030039

Analysing interventions designed to reduce tuberculosis-related stigma: A scoping review.

Isabel Foster, Michelle Galloway, Wieda Human, Michaile Anthony et al. • PLOS Global Public Health (2022)

Stigma is a critical barrier for TB care delivery; yet data on stigma reduction interventions is limited. This review maps the available literature on TB stigma reduction interventions, using the Health Stigma and Discrimination framework a...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pgph.0000989

Spatial patterns in the contribution of biotic and abiotic factors to the population dynamics of three freshwater fish species

Mathieu Chevalier, Pablo Tedesco, Gael Grenouillet • PeerJ (2022)

Background Population dynamics are driven by a number of biotic (e.g., density-dependence) and abiotic (e.g., climate) factors whose contribution can greatly vary across study systems (i.e., populations). Yet, the extent to which the contri...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.12857

Classifying Characteristics of Opioid Use Disorder From Hospital Discharge Summaries Using Natural Language Processing

Melissa N. Poulsen, Philip J. Freda, Vanessa Troiani, Anahita Davoudi et al. • Frontiers in Public Health (2022)

BackgroundOpioid use disorder (OUD) is underdiagnosed in health system settings, limiting research on OUD using electronic health records (EHRs). Medical encounter notes can enrich structured EHR data with documented signs and symptoms of O...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2022.850619

Bias and Fairness in Natural Language Processing

Kai-Wei Chang, Vinod M. Prabhakaran, Vicente Ordóñez • Conference on Empirical Methods in Natural Language Processing (EMNLP) (2019)

Recent advances in data-driven machine learning techniques (e.g., deep neural networks) have revolutionized many natural language processing applications. These approaches automatically learn how to make decisions based on the statistics an...

OPENALEX

Few-shot learning for automated content analysis: Efficient coding of arguments and claims in the debate on arms deliveries to Ukraine

Jonas Rieger, Kostiantyn Yanchenko, Mattes Ruckdeschel, Gerret von Nordheim et al. • Studies in Communication, Media (2024)

Pre-trained language models (PLM) based on transformer neural networks developed in the field of natural language processing (NLP) offer great opportunities to improve automatic content analysis in communication science, especially for the ...

DOAJ Open Access (DOAJ) DOI: 10.5771/2192-4007-2024-1-72

Natural language processing applied to mental illness detection: a narrative review

Tianlin Zhang, Annika Marie Schoene, Shaoxiong Ji, Sophia Ananiadou • npj Digital Medicine (2022)

Mental illness is highly prevalent nowadays, constituting a major cause of distress in people's life with impact on society's health and well-being. Mental illness is a complex multi-factorial disease associated with individual risk factors...

OPENALEX cc-by DOI: https://doi.org/10.1038/s41746-022-00589-7 PMC: 8993841

Evaluation of the accuracy of ChatGPT-4 and Gemini’s responses to the World Dental Federation’s frequently asked questions on oral health

Aysenur Arpaci, Asel Usdat Ozturk, Ismail Okur, Sanaz Sadry • BMC Oral Health (2025)

Abstract Background The field of artificial intelligence (AI) has experienced considerable growth in recent years, with the advent of technologies that are transforming a range of industries, including healthcare and dentistry. Large langua...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12903-025-06624-9

Which factors influence public perceptions of urban attractions? — A comparative study

Zhonglin Tang, Yihui Zhao, Min Fu, Yuting Wang et al. • Ecological Indicators (2023)

To better serve the public, urban attractions must understand the public's likes and dislikes and continually adapt and optimize their service in response. However, traditional methods for gauging public opinion, such as questionnaires and ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ecolind.2023.110541