Academic Articles & Research Papers

Health Technology Assessment in Osteoporosis

We review the various aspects of health technology assessment in osteoporosis, including epidemiology and burden of disease, and assessment of the cost-effectiveness of recent advances in the treatment of osteoporosis and the prevention of ...

Fine mapping of QYrsv.swust-1BL for resistance to stripe rust in durum wheat Svevo

Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is a serious disease that affects wheat worldwide. There is a great need to develop cultivars with combinations of all-stage resistance (ASR) and adult-plant resistance (APR)...

Semi-rational design and modification of phosphoketolase to improve the yield of tyrosol in Saccharomyces cerevisiae

Tyrosol is an important component of pharmaceuticals, nutraceuticals, and cosmetics, and their biosynthetic pathways are currently a hot research topic. d-Erythrose 4-phosphate is a key precursor for the biosynthesis of tyrosol in Saccharom...

Correction: Aging, the microbiota–gut–brain axis, and late-life epilepsy: a hypothesis-driven review

Clinical and cost-effectiveness of a standardised diagnostic assessment for children and adolescents with emotional difficulties: the STADIA multi-centre RCT

Background Emotional disorders are common in children and young people and can significantly impair their quality of life. Evidence-based treatments require a timely and appropriate diagnosis. The utility of standardised diagnostic assessme...

Health Technology and Reproduction

Kathleen M. Hoeger, MD, MPH Terhi T. Piltonen, MD, PhD The current issue of Seminars in Reproductive Medicine is devoted to a review of the burgeoning role of health technology in the field of reproductive medicine. The guest editor for the...

Anticancer and anti-angiogenic activities of mannooligosaccharides extracted from coconut meal on colorectal carcinoma cells in vitro

Colorectal carcinoma (CRC) is one of the most common malignancies, though there are no effective therapeutic regimens at present. This study aimed to investigate the inhibitory effects of mannooligosaccharides extracted from coconut meal (C...

Health technology innovations

The global pandemic has drastically impacted older adults in numerous ways (e.g., loneliness; age discrimination; mental and physical health; limited access to traditional health care).On the other hand, it may have accelerated the general ...

Effects of an infant formula containing a whey protein concentrate on feeding tolerance and markers of intestinal immune defense in Chinese infants

Abstract Background Human milk (HM) bioactive components can have immune modulatory functions, impact the gut microbiome, and may result in functional benefits when added to infant formula (IF). In this single-arm, prospective, intervention...

Editorial Summer 2025

Early childhood education (ECE) lays the foundation for a child's lifelong learning journey. More and more, new insights and understandings of child development are evolving, and concomitantly, new preschool education has seen several excit...

Reported Challenges in Health Technology Assessment of Complex Health Technologies

OBJECTIVES: With complex health technologies entering the market, methods for health technology assessment (HTA) may require changes. This study aimed to identify challenges in HTA of complex health technologies. METHODS: A survey was sent ...

Health Technology Assessment

The term health technology refers to drugs, devices, and programs that can improve and extend quality of life. As decision-makers struggle to find ways to reduce costs while improving health care delivery, health technology assessments (HTA...

Studies in Health Technology and Informatics

Exploring barriers and enablers to implementing a digital mental health crisis risk mitigation pathway in acute paediatric care: A multi-site, exploratory mixed-methods study

Objective Children and young people (CYP) presenting in mental health crisis to acute paediatric settings represent a growing clinical and system-level challenge. These environments, primarily designed for physical healthcare, frequently la...

Demonstration of high value care to improve oral health of a remote Indigenous community in Australia

Abstract Background The oral health of Indigenous children in remote communities is much worse than other population groups in Australia. Providing and maintaining an oral health service is challenging due to the remoteness of communities, ...

Association between social health status and health-related quality of life among community-dwelling elderly in Zhejiang

Abstract Background Population aging is an inevitable trend and previous studies have showed the relationship between social health related factors and health-related quality of life (HR-QOL) in the elderly. The objective of this study is t...

Reducing Alert Fatigue by Sharing Low-Level Alerts With Patients and Enhancing Collaborative Decision Making Using Blockchain Technology: Scoping Review and Proposed Framework (MedAlert)

BackgroundClinical decision support (CDS) is a tool that helps clinicians in decision making by generating clinical alerts to supplement their previous knowledge and experience. However, CDS generates a high volume of irrelevant alerts, res...

Online peer support for Young Onset Dementia is a promising resource, but not a panacea: a commentary from the INTERDEM Young Onset Dementia taskforce

Web-based versus simulation-based refresher training in newborn life support

Background: Regular training for healthcare professionals in newborn life support is life-saving. Web-based refresher has the potential to be non-inferior to simulation-based refresher training. Methods: The multicenter non-inferiority rand...

Examining the characteristic features of lipedema and the usefulness of BMI and WHtR in clinical evaluation

Abstract Background Lipedema is an adipose tissue disorder involving mostly women. One of the most characteristic lipedema symptoms is painful accumulation of adipose tissue in lower and upper extremities leading to disproportion. Due to th...