Academic Articles & Research Papers

Framing the Public Health of Caregiving

Caregiving has only recently been acknowledged by the nation as an important topic for millions of Americans. A psychological or sociological approach to care-giving services has been most often applied, with little attention to the populat...

Unlocking the Power of Eggs: Nutritional Insights, Bioactive Compounds, and the Advantages of Omega-3 and Omega-6 Enriched Varieties

This study explores the nutritional benefits and health implications of omega-3- and omega-6-enriched eggs, positioning them within the context of functional foods aimed at improving public health outcomes. With rising consumer interest in ...

Public health significance of neuroticism.

The personality trait of neuroticism refers to relatively stable tendencies to respond with negative emotions to threat, frustration, or loss. Individuals in the population vary markedly on this trait, ranging from frequent and intense emot...

LASIK Surgery

Photo by Scott Van Daalen on Unsplash INTRODUCTION LASIK surgery, one of the most common elective procedures worldwide, aims to decrease or eliminate the need to wear glasses or contact lenses by reshaping the cornea’s curvature to re...

Clinical characteristics of and risk factors for secondary bloodstream infection after pneumonia among patients infected with methicillin-resistant Staphylococcus aureus

Purpose: To investigate the clinical features and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia (MP) with secondary MRSA bloodstream infections (MRSA-BSI) (termed MP-BSI) compared with MP alone and to study t...

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

Abstract Background Gastric Cancer (GC) is the fourth most deadly cancer worldwide. Enhanced understanding of its key epidemiological and molecular drivers is urgently needed to lower the incidence and improve outcomes. Furthermore, tumor b...

Novel CTLA4 Haploinsufficiency with Pure Red Cell Aplasia as the Core Manifestation: Insights from a Sibling Pair with Divergent Tumorigenic Outcomes.

Cardiovascular and metabolic outcomes associated with moderate-to-severe atopic dermatitis: A systematic review and meta-analysis

Background: Chronic systemic inflammation in individuals with moderate-to-severe atopic dermatitis (AD) potentially predisposes them to metabolic and cardiovascular diseases. Nevertheless, evidence with regard to such association is limited...

Impact of Blood Transfusions After Kidney Transplantation on Clinical Outcomes and Broadness of Sensitisation.

Fundamental Immunology

The first great revolution in immunology is credited to Louis Pasteur. Among the many achievements stemming from that early period is the elimination of smallpox from the entire world in 1977, a century later. The second great revolution, b...

Improving Muscle Function Through a Multimodal Behavioural Intervention for Knee Osteoarthritis and Obesity: The POMELO Trial

ABSTRACT Background Treatments aimed at improving physical function and body composition, including reducing fat mass (FM) and increasing muscle mass, may benefit individuals with advanced knee osteoarthritis (OA) and obesity. We investigat...

Probiotics in Nanotechnology-Driven Wound Healing: From Mechanistic Insight to Clinical Promise

Chronic wounds, including diabetic foot ulcers and pressure sores, are becoming more prevalent due to aging populations and increased metabolic problems. These wounds often persist due to impaired healing, chronic inflammation, oxidative st...

Hardy-Leindler-Type Inequalities via Conformable Delta Fractional Calculus

In this article, some fractional Hardy-Leindler-type inequalities will be illustrated by utilizing the chain law, Hölder’s inequality, and integration by parts on fractional time scales. As a result of this, some classical integral inequali...

An Unsupervised and End-to-End Registration Method Using Offset Field and Pseudodata for Video SAR Images

Video synthetic aperture radar (video SAR) has been successfully applied in many fields and the registration of the video SAR images has been proven to be a crucial step in their preprocessing. However, video SAR images exhibit more severe ...

Topical Pharmacological Treatment of Actinic Keratoses: Focus on Tirbanibulin 1% Ointment

Actinic keratosis (AK) is a frequent precancerous skin lesion that mostly affects chronically sun-exposed areas. Chronic sun damage leads to various mutations in onco-suppressor and oncogenic genes which cause an uncontrolled proliferation ...

Prevalence, predictors and pregnancy outcomes of unprescribed and herbal medicine use in Ibadan, Nigeria

Abstract Background Unprescribed and herbal medicines use among pregnant women is a public health concern in low and middle-income countries because of the potential teratogenic effects, insufficient safety and weak drug regulatory systems....

Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson’s Disease

Parkinson’s disease (PD) is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH). The aim of our study was to establish whether patients with PD and visual hallucinations (PDH+) have s...

Variation in TMEM106B in chronic traumatic encephalopathy

Abstract The genetic basis of chronic traumatic encephalopathy (CTE) is poorly understood. Variation in transmembrane protein 106B (TMEM106B) has been associated with enhanced neuroinflammation during aging and with TDP-43-related neurodege...

Niclosamide nanoparticles enhance pancreatic cancer sensitivity to gemcitabine via HIF-1α inhibition

Summary: Pancreatic cancer (PC) exhibits profound metabolic adaptations that support tumor progression, survival, and therapy resistance. Hypoxia-inducible factor-1α (HIF-1α) is a key regulator of these processes, promoting metabolic reprog...

Small cell neuroendocrine carcinoma of the cervix: From molecular basis to therapeutic advances

Small cell neuroendocrine carcinoma of the cervix (SCNECC) is an uncommon but aggressive uterine malignancy, the cause of which is generally associated with human papillomavirus (HPV) infection. A lack of clinical trials and evidence-based ...