Reset
Showing 20 of 2,154 academic articles

Isoliquiritigenin Attenuates Staphylococcus aureus Adhesion and Invasion to Counteract Staphylococcus aureus Pathogenicity and Infection

Lili Tian, Lili Tian, Jian Sun, Hong Jiang et al. • Frontiers in Cellular and Infection Microbiology (2025)

IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) is a major clinical challenge due to its virulence and multidrug resistance. Antivirulence strategies targeting key pathogenic mechanisms without affecting bacterial viability p...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2025.1686699

Identification and genomic characterization of a novel porcine parvovirus in China

Yajing Guo, Guangzhi Yan, Shengnan Chen, Hui Han et al. • Frontiers in Veterinary Science (2022)

Porcine parvoviruses (PPVs) are a group of small non-enveloped viruses with seven species (porcine parvovirus 1–7, PPV1-7) have been identified. In this study, a novel porcine parvovirus, provisionally named porcine parvovirus 8 (PPV8), was...

DOAJ Open Access (DOAJ) DOI: 10.3389/fvets.2022.1009103

Motivation and context of concurrent stimulant and opioid use among persons who use drugs in the rural United States: a multi-site qualitative inquiry

R. J. Fredericksen, R. Baker, A. Sibley, A. T. Estadt et al. • Harm Reduction Journal (2024)

Abstract Background In recent years, stimulant use has increased among persons who use opioids in the rural U.S., leading to high rates of overdose and death. We sought to understand motivations and contexts for stimulant use among persons ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12954-024-00986-z

Implementation of the therapeutic use of hydroxyurea for sickle cell disease management in resource-constrained settings: a systematic review of adoption, cost and acceptability

Joyce Gyamfi, Temitope Ojo, Dorice Vieira, Nessa Ryan et al. • BMJ Open (2020)

Objectives Mortality associated with sickle cell disease (SCD) is high in many low- and middle-income countries (LMICs). Hydroxyurea, a medicine to effectively manage SCD, is not widely available in resource-constrained settings. We identif...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2020-038685

Point of Care Ultrasonographic Life Support in Emergency (PULSE)—a quasi-experimental study

Noman Ali, Abdul Ahad Chhotani, Sannia Perwaiz Iqbal, Salman Muhammad Soomar et al. • International Journal of Emergency Medicine (2023)

Abstract Background Many physicians use point-of-care ultrasound (PoCUS) in their clinical practice to improve their diagnostic capabilities, accuracy, and timeliness. Over the last two decades, the use of PoCUS in the emergency room has dr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12245-023-00525-w

Screen Out Anaemia Among Adolescent Boys as Well!

Dheeraj Gupta, Bhawana Pant, Ranjeeta Kumari, Monika Gupta • National Journal of Community Medicine (2013)

Background: Adolescence – a period of transition between childhood and adulthood is a significant period of human growth and maturation. Adolescents represent about a fifth of India’s population. Many studies in recent times have highlighte...

DOAJ Open Access (DOAJ)

Infrared Thermographic Evaluation Following Hemilaminectomy in Dogs with Thoracolumbar Intervertebral Disc Extrusion: A Pilot Study

Cristian Zaha, Larisa Schuszler, Liliana Cărpinișan, Alina Ghișe et al. • Animals (2026)

(1) Background: Intervertebral Disc Disease (IVDD) represents one of the most frequently encountered neurological disorders in canine patients and often necessitates surgical decompression by means of hemilaminectomy. Objective methods for ...

DOAJ Open Access (DOAJ) DOI: 10.3390/ani16121796

Leveraging AI to optimize vaccines supply chain and logistics in Africa: opportunities and challenges

Sulaiman Muhammad Musa, Usman Abubakar Haruna, Lukman Jibril Aliyu, Mubarak Zubairu et al. • Frontiers in Pharmacology (2025)

Examining the current situation of the vaccine supply chain in Africa, the article highlights the importance of AI technologies while outlining the prospects and problems in vaccine supply chain management in Africa. Despite the significanc...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2025.1531141

The role of drug treatment and recovery services: an opportunity to address injection initiation assistance in Tijuana, Mexico

Stephanie A. Meyers, Claudia Rafful, Sonia Jain, Xiaoying Sun et al. • Substance Abuse Treatment, Prevention, and Policy (2020)

Abstract Background In the U.S. and Canada, people who inject drugs’ (PWID) enrollment in medication-assisted treatment (MAT) has been associated with a reduced likelihood that they will assist others in injection initiation events. We aime...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13011-020-00322-1

The impact of perception on institutional delivery service utilization in Northwest Ethiopia: the health belief model

Adane Nigusie, Telake Azale, Mezgebu Yitayal, Lemma Derseh • BMC Pregnancy and Childbirth (2022)

Abstract Background Ethiopia has been striving to promote institutional delivery through community wide programs. However, home is still the preferred place of delivery for most women encouraged by the community`s perception that delivery i...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12884-022-05140-w

Barriers and opportunities for clinical trials in Bahrain: a qualitative study of key opinion leaders

Jamil Ahmed, Angeleena Esther, Hussein AlHafnawi, Mohamed Hany Shehata et al. • BMJ Open (2026)

Background and objectives Clinical trials are essential for advancing scientific knowledge and improving patient outcomes. In the last decade, Bahrain has made notable progress in healthcare. However, clinical trial participation from the r...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2026-117241

Evolution of traditional Chinese medicine registration review and approval policies: research based on the LDA topic model

Kaidi Lu, Ming Xie, Wanping Sun, Yiming Liu • Frontiers in Public Health (2025)

IntroductionThe economic expansion of the Traditional Chinese Medicine (TCM) industry has prompted the Chinese government to introduce a series of policies focused on the registration review and approval of TCM. These policies aim to provid...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2025.1655636

Challenges and experience of the Ethiopian rural health extension program: implications for reform and revitalization

Taddese Alemu Zerfu, Amare Abera Tareke, Sibhatu Biadgilign • BMC Health Services Research (2023)

Abstract Background Despite remarkable gains over the past decade, mounting evidence suggests that Ethiopia’s rural health extension program (HEP) is facing serious implementation challenges. We investigated the current and potential future...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-023-10253-9

Estimating the number of cardio-pulmonary events potentially averted by fine particulate matter air quality index activity guidelines

Robert D Brook, Pia-Allison Roa, Phillip D Levy, Samantha J Bauer et al. • American Journal of Preventive Cardiology (2025)

Background: Fine particulate matter 100 for PM2.5) for 3 groups (healthy adults, ASCVD and pulmonary disease patients) in the US during 2022. The theoretical number of adverse events potentially prevented per county was estimated each day a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ajpc.2025.101266

Trait impulsivity prospectively predicts lower methadone treatment retention: moderation by pain catastrophizing

Annabelle M. Belcher, Kristen R. Hamilton-Moseley, Ebonie Massey, Mark Yoon et al. • Addiction Science & Clinical Practice (2026)

Abstract Background Empirical evidence supports the use of methadone as the standard of care for opioid use disorder. However, low retention in methadone treatment is one of the largest impediments to treatment success. Although several psy...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13722-026-00699-7

Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review.

John Danesh, Stephen Kaptoge, Andrea G Mann, Nadeem Sarwar et al. • PLoS Medicine (2008)

BackgroundThe relevance to coronary heart disease (CHD) of cytokines that govern inflammatory cascades, such as interleukin-6 (IL-6), may be underestimated because such mediators are short acting and prone to fluctuations. We evaluated asso...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pmed.0050078

Effectiveness of echocardiography and cardiac magnetic resonance for screening and monitoring cardiomyopathy in people living with HIV: a mixed-methods systematic review protocol

Flávia Figueira, Matheus de Sá Freitas Tavares, Carla Betina Andreucci, Bernardino Geraldo Alves Souto et al. • Systematic Reviews (2026)

Abstract Background People living with HIV (PLWH) have a markedly increased risk of cardiovascular disease (CVD), including cardiomyopathy, due to a complex interplay of chronic inflammation, viral persistence, and antiretroviral therapy (A...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13643-026-03091-3

Sleep behaviours and associated habits and the progression of pre-diabetes to type 2 diabetes mellitus in adults: A systematic review and meta-analysis

Samiul A Mostafa, Sandra Campos Mena, Christina Antza, George Balanos et al. • Diabetes & Vascular Disease Research (2022)

Introduction Certain sleep behaviours increase risk of type 2 diabetes mellitus (T2DM) in the general population, but whether they contribute to the progression from pre-diabetes to T2DM is uncertain. We conducted a systematic review to ass...

DOAJ Open Access (DOAJ) DOI: 10.1177/14791641221088824

Coronary artery bypass grafting outcomes of patients with human immunodeficiency virus: a population-based study of National Inpatient Sample from 2015 to 2020

Renxi Li, Deyanira J. Prastein, Brian G. Choi • Scientific Reports (2024)

Abstract Individuals affected by human immunodeficiency virus (HIV) have a growing demand for coronary artery bypass grafting (CABG) due to heightened risk for cardiovascular diseases and extended life expectancy. However, CABG outcomes in ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-65518-y

A pre- and post-operative protocol for assessment of voice and swallowing function in patients undergoing heart or lung transplantation

Rebecca Black, BApSc, Speech Pathologist(SP), Duy Duong Nguyen, MD PhD, Anna Miles, PhD, Daniel Novakovic, MBBS, FRACS, MPH et al. • JHLT Open (2025)

Background: Oropharyngeal dysphagia and laryngeal dysfunction are complications of lung and heart transplantation. However, there is a lack of understanding around pre-operative function and an absence of standardized assessment protocols. ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jhlto.2025.100261