Academic Articles & Research Papers

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

Abstract The SARS-CoV-2 virus caused the most severe pandemic around the world, and vaccine development for urgent use became a crucial issue. Inactivated virus formulated vaccines such as Hepatitis A and smallpox proved to be reliable appr...

Formation and stability of oil-in-water nanoemulsions containing rice bran oil: <it>in vitro </it>and <it>in vivo </it>assessments

Abstract Background Nanoemulsions have practical application in a multitude of commercial areas, such as the chemical, pharmaceutical and cosmetic industries. Cosmetic industries use rice bran oil in sunscreen formulations, anti ageing prod...

Peptide-functionalized periodic mesoporous silica nanoparticles for monocyte-specific TET3 Silencing enhance cardiac repair after acute myocardial infarction

Abstract Modulating the balance between pro- and anti-inflammatory monocyte subsets holds therapeutic promise in acute myocardial infarction (AMI); however, effective and selective strategies are still lacking. In this study, we are the fir...

Optimally biosynthesized, PEGylated gold nanoparticles functionalized with quercetin and camptothecin enhance potential anti-inflammatory, anti-cancer and anti-angiogenic activities

Abstract Background The development of nano delivery systems is rapidly emerging area of nanotechnology applications where nanomaterials (NMs) are employed to deliver therapeutic agents to specific site in a controlled manner. To accomplish...

High level non-carbapenemase carbapenem resistance by overlaying mutations of mexR, oprD, and ftsI in Pseudomonas aeruginosa

ABSTRACT Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global threat, but the mechanism of non-carbapenemase carbapenem resistance is still unclear. In the current study, we investigated the contributions of point mutations in mex...

Bioremediation of Persistent Organic Pollutant—Oxybenzone with <i>Pleurotus djamor</i>

Oxybenzone, a common sunscreen ingredient, has been widely detected in various environmental matrices, posing significant ecological and health risks. The present study demonstrates, for the first time, the capacity of Pleurotus djamor to d...

Genetic signatures of exceptional longevity: a comprehensive analysis of coding region single nucleotide polymorphisms (SNPs) in centenarians and supercentenarians

Abstract Aging, a complex biological process, entails sequential changes in organisms that elevate the risk of frailty, disease, and mortality, affecting individuals at the level of cellular, organ, and organism. This process is influenced ...

Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

In association with the published article “Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy” (Huang et al., 2017) [1], this data article contains information about deSUMOylat...

The antibiogram of Pus cultures in Federal Tertiary Care Hospital, Islamabad and its utility in antimicrobial stewardshipThe antibiogram of pus cultures in federal tertiary care hospital, Islamabad and its utility in antimicrobial stewardship

Background and Objectives: Antimicrobial resistance has emerged as a significant global health threat. Infections caused by Multi Drug-Resistant (MDR) bacteria pose formidable challenges in terms of treatment options and patient outcomes. P...

SIRT1 and miR-34a as Potential Plasma Biomarkers in the Acute Phase of Ischemic Stroke

Stroke is the major cause of disability and mortality worldwide. Identification of molecular biomarkers in the early hours after stroke is important in terms of both diagnostic and therapeutic applications. miR-34a, a highly expressed miRNA...

Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome

Introduction: Pneumococcal vaccination has significantly decreased the burden of invasive pneumococcal disease in the general population, however studies on effectiveness in Down syndrome (DS) are heterogeneous. In this cross-sectional stud...

Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia

Abstract Mercaptopurine intolerance is an adverse effect of mercaptopurine administration in pediatric patients with acute lymphoblastic leukemia (ALL). NUDT15 variants have emerged as major determinants of mercaptopurine intolerance, espec...

The Advancement of Medical Biotechnology in Developing Countries: Economic Opportunities and Challenges

Starting from decades ago, medical biotechnology has revolutionized the healthcare industry by offering new hopes for previously untreatable diseases and improving overall health outcomes. To explore the advancements in medical biotechnolog...

Subject and Course Guides: Medical Biotechnology: Associations and Organizations

A compilation of resources for researchers, faculty, and students in the Medical Biotechnology Program....

[Safety problems in biotechnology. Medical biotechnology and safety].

RECENT ADVANCES IN MEDICAL BIOTECHNOLOGY AND INNOVATIVE THERAPEUTIC TECHNOLOGIES

Abstract: Medical biotechnology has emerged as a transformative field that integrates molecular biology, genetics, bioinformatics, nanotechnology, and biomedical engineering to improve the prevention, diagnosis, and treatment of human disea...

A Study on Medical Biotechnology System from Legal Perspective

With the progress and development of science and technology, medical biotechnology has made great progress, which created an objective market and lucrative returns for the medical and health industry as well as provided assistance for patie...

Prospects of nanoparticle–DNA binding and its implications in medical biotechnology

Medical & biotechnology applications

Oily start towards a medical biotechnology institute.

It is all about bringing scientific discovery in the medical biotechnology field to the bedside of patients \nwho need it, for which an institute is required to transfer the technology from the academic environment \ninto products for the m...