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Prefrontal cortical deficits are a putative susceptibility factor for PTSD

Rebecca Nalloor, Rebecca Nalloor, Khadijah Shanazz, Khadijah Shanazz et al. • Frontiers in Behavioral Neuroscience (2026)

IntroductionOnly a subset of people who experience a traumatic event develop Post-Traumatic Stress Disorder (PTSD) suggesting that there are susceptibility factors influencing PTSD pathophysiology. While post trauma sequelae factors are ext...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnbeh.2026.1750991

Toward an integrated approach for mental health and psychosocial support and peacebuilding in North-East Nigeria: programme description and preliminary outcomes from ‘Counselling on Wheels’

Sharli Paphitis, Fatima Akilu, Natasha Chilambo, Abiye Iruayenama et al. • BJPsych Open (2023)

Background Despite theoretical support for including mental health and psychosocial support (MHPSS) with peacebuilding, few programmes in conflict-affected regions fully integrate these approaches. Aims To describe and assess preliminary o...

DOAJ Open Access (DOAJ) DOI: 10.1192/bjo.2023.575

The Immunomodulatory and Anti-Inflammatory Effect of Curcumin on Immune Cell Populations, Cytokines, and In Vivo Models of Rheumatoid Arthritis

Sebastian Makuch, Kamil Więcek, Marta Woźniak • Pharmaceuticals (2021)

Rheumatoid arthritis (RA) is a widespread chronic autoimmune disorder affecting the joints, causing irreversible cartilage, synovium, and bone degradation. During the course of the disease, many immune and joint cells are activated, causing...

DOAJ Open Access (DOAJ) DOI: 10.3390/ph14040309

Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study

Pasquale Ambrosino, Ilenia Calcaterra, Antonio Molino, Pasquale Moretta et al. • Biomedicines (2021)

Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its disabling complications. We designed a case-control study to assess the alterations of endothelium-dependent flow-mediated...

DOAJ Open Access (DOAJ) DOI: 10.3390/biomedicines9080957

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

Sarah L. Baines, Kathryn E. Holt, Mark B. Schultz, Torsten Seemann et al. • mBio (2015)

ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden. The globally dominant sequence type 239 (ST239) HA-MRSA clone has persiste...

DOAJ Open Access (DOAJ) DOI: 10.1128/mBio.00080-15

Genetic signatures of exceptional longevity: a comprehensive analysis of coding region single nucleotide polymorphisms (SNPs) in centenarians and supercentenarians

Audre Preena Maria Sundar Raj, Gayathri Selvakumar, James Clement, George M. Church et al. • Human Genomics (2025)

Abstract Aging, a complex biological process, entails sequential changes in organisms that elevate the risk of frailty, disease, and mortality, affecting individuals at the level of cellular, organ, and organism. This process is influenced ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40246-025-00772-3

Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome

Antonio Musolino, Marco Roversi, Mariateresa Romaniello, Vittorio Scoppola et al. • Vaccine: X (2025)

Introduction: Pneumococcal vaccination has significantly decreased the burden of invasive pneumococcal disease in the general population, however studies on effectiveness in Down syndrome (DS) are heterogeneous. In this cross-sectional stud...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jvacx.2025.100744

Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia

Chih-Hsiang Yu, Ya-Hsuan Chang, Der-Shiun Wang, Shiann-Tarng Jou et al. • Scientific Reports (2023)

Abstract Mercaptopurine intolerance is an adverse effect of mercaptopurine administration in pediatric patients with acute lymphoblastic leukemia (ALL). NUDT15 variants have emerged as major determinants of mercaptopurine intolerance, espec...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-27720-2

Expression Profiles of IGF1, EGF, and FGF2 Genes in Patients With Prostate Cancer in Isfahan Province, Iran

Farinaz Khosravian, Fatemeh Ketabchi, Nasrin Hadi, Faezeh Namazi et al. • Research in Molecular Medicine (2019)

Background: Prostate cancer is the second most prevalent cancer among men all over the world. Over the past 10 years, prostate cancer prevalence has increased in Iran. Growth factors have an important role in the regulation and growth of ma...

DOAJ Open Access (DOAJ)

Investigating the genetic makeup of the major histocompatibility complex (MHC) in the United Arab Emirates population through next-generation sequencing

Nour al dain Marzouka, Halima Alnaqbi, Amira Al-Aamri, Guan Tay et al. • Scientific Reports (2024)

Abstract The Human leukocyte antigen (HLA) molecules are central to immune response and have associations with the phenotypes of various diseases and induced drug toxicity. Further, the role of HLA molecules in presenting antigens significa...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-53986-1

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450

Absence of Asymptomatic Malaria Infection in Endemic Area of Bashagard District, Hormozgan Province, Iran

H Turki, S Zoghi, A A Mehrizi, S Zakeri et al. • Iranian Journal of Parasitology (2012)

Background: A successful malaria elimination program calls for enough attention to parasite carri­ers, especially asymptomatic malaria, as well as the diagnosis and treatment of clinical cases. Asymptomatic malaria is an infection that pati...

DOAJ Open Access (DOAJ)

Social Media Listening to Understand the Lived Experience of Individuals in Europe With Metastatic Breast Cancer: A Systematic Search and Content Analysis Study

Manuelita Mazza, Maria Piperis, Sathyaraj Aasaithambi, Jyoti Chauhan et al. • Frontiers in Oncology (2022)

BackgroundDespite a wealth of real-world data on metastatic breast cancer (mBC), insights into the lived experience are lacking. This study aimed to explore how the lived experience of mBC is described on social media.MethodsA predefined se...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.863641

The impact of the student-supervisor relationship on graduate student mental health: An integrative review

Huma Khalid, Sandra Della Porta • Social Sciences and Humanities Open (2026)

In recent years, the mental health of graduate students has become a prominent concern in higher education, with many students experiencing elevated levels of stress, anxiety, depression, burnout, and psychological distress. These challenge...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ssaho.2026.103794

Monitoring development from 0–6 years: an online system, standardized for Dutch children

Anneloes Van Baar, Marjolein Verhoeven, David Hessen, Liesbeth de Paauw-Telman et al. • Frontiers in Developmental Psychology (2025)

BackgroundMonitoring and screening children's development from infancy into early childhood is important for prevention purposes, as potential delay may best be addressed as soon as possible. For an efficient monitoring system, standardized...

DOAJ Open Access (DOAJ) DOI: 10.3389/fdpys.2025.1727158

Developing and defining core climate and environmental epidemiology competencies for field epidemiology training programs in the Eastern Mediterranean Region: a Delphi study

Yousef Khader, Muhammad Sartaj, Mohannad Al Nsour, Ruba Kamal Alsouri et al. • Frontiers in Public Health (2026)

BackgroundClimate change, environmental degradation, and chemical hazards increasingly shape population health risks, particularly in the Eastern Mediterranean Region (EMR), where water scarcity, rapid urbanization, conflict, and fragile he...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2026.1902013

Social Justice Mathematics and Public Health Equity: A Systematic Review of Quantitative Literacy in Health Decision-Making

Terungwa James Age • GHMJ (Global Health Management Journal) (2026)

Background: Public health decision-making increasingly requires individuals to interpret numerical information such as risks, probabilities, treatment benefits, and epidemiological trends. However, disparities in quantitative literacy may c...

DOAJ Open Access (DOAJ) DOI: 10.35898/ghmj-931337