Home »
Academic Articles & Research Papers
Showing 20 of 134 academic articles
Liangsheng Xu, Weidong Chen • Molecular Plant-Microbe Interactions
(2013)
Agrobacterium-mediated transformation (AMT) was used to identify potential virulence factors in Sclerotinia sclerotiorum. Screening AMT transformants identified two mutants showing significantly reduced virulence. The mutants showed growth ...
DOAJ
Open Access (DOAJ)
DOI: 10.1094/MPMI-07-12-0177-R
M. Iftakhar Alam, Jafrin Sultana • Austrian Journal of Statistics
(2019)
One of the most challenging tasks in clinical trials is finding the maximum tolerated dose (MTD) to be tested in the next phase. An assurance for the safety of the patients and recommendation of a suitable dose for phase II are the main obj...
DOAJ
Open Access (DOAJ)
DOI: 10.17713/ajs.v48i5.883
N. N. Besednova, T. N. Zvyagintseva, B. G. Andriukov, T. S. Zaporozhets et al. • Антибиотики и Химиотерапия
(2021)
The review presents materials describing the seaweed-derived sulfated polysaccharides (SPS) as potential means for prevention and treatment of viral diseases of the respiratory tract, mainly influenza and COVID-19. The literature materials o...
DOAJ
Open Access (DOAJ)
DOI: 10.37489/0235-2990-2021-66-7-8-50-66
Heabin Kim, Hyun-Taek Kim, Seung-Hyun Jung, Jong Won Han et al. • Marine Drugs
(2023)
The discovery of new highly effective anticancer drugs with few side effects is a challenge for drug development research. Natural or synthetic anticancer peptides (ACPs) represent a new generation of anticancer agents with high selectivity...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/md21120607
Min Kyoung Shin, In-Wook Hwang, Bo-Young Jang, Kyung-Bin Bu et al. • Antibiotics
(2023)
With the increasing challenge of controlling infectious diseases due to the emergence of antibiotic-resistant strains, the importance of discovering new antimicrobial agents is rapidly increasing. Animal venoms contain a variety of function...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/antibiotics12121708
Shreesh Raj Sammi, Shreesh Raj Sammi, Laura E. Jameson, Kendra D. Conrow et al. • Frontiers in Toxicology
(2022)
Neurological hazard assessment of industrial and pesticidal chemicals demands a substantial amount of time and resources. Caenorhabditis elegans is an established model organism in developmental biology and neuroscience. It presents an idea...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/ftox.2022.826488
Hao Tang, Ting Qin, Zhiwen Yan, Changqing Li et al. • Frontiers in Neuroscience
(2026)
ObjectiveDioctyl terephthalate (DOTP), a widely used plasticizer in food packaging and environmental materials, has raised concerns regarding its potential impact on human health. This study aims to investigate the neurotoxicity-related mec...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnins.2026.1783807
Nargiz Parkhatkyzy, Alma Shukirbekova, Zumrad Usmanalieva, Kundyzay Mirzakir et al. • Journal of Pharmacy & Pharmacognosy Research
(2026)
Context: The use of pregabalin in neuropathic pain management has been increasingly associated with concerns regarding toxicity, particularly in cases of overdose, misuse, and co-exposure with central nervous system depressants. In parallel...
DOAJ
Open Access (DOAJ)
DOI: 10.56499/jppres_14.3.2550
Atefeh Varmazyari, Ali Taghizadehghalehjoughi, Cigdem Sevim, Ozlem Baris et al. • Toxicology Reports
(2020)
Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nano...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.toxrep.2020.04.011
Gomaa Mostafa-Hedeab, Amany Behairy, Yasmina M. Abd-Elhakim, Amany Abdel-Rahman Mohamed et al. • Antioxidants
(2023)
This study assessed the possible protective role of green synthesized zinc oxide nanoparticles using Moringa olifera leaf extract (MO-ZNPs) in acrylamide (ACR)-induced reproductive dysfunctions in male rats. ACR (20 mg/kg b.wt/day) and/or M...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/antiox12020361
Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes
(2024)
Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/fishes9020076
Shiro Okumura, Hironori Koga, Kuniyo Inouye, Eiichi Mizuki • Toxins
(2014)
Parasporin-4 (PS4) is an aerolysin-type β-pore-forming toxin produced by Bacillus thuringiensis strain A1470. It exhibits specific cytotoxicity against human cancer cell lines; therefore, it is expected to be useful for the diagnosis and tr...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/toxins6072115
Li-Tao Che, Li-Tao Che, Ahmed H. El-Sappah, Ahmed H. El-Sappah et al. • Frontiers in Veterinary Science
(2025)
IntroductionThis study investigated whether glycyrrhetinic acid (GA) can alleviate the reproductive toxicity of Zearalenone (ZEN) in replacement gilts.MethodsEighty Landrace × Yorkshire gilts were randomly assigned to four dietary groups: c...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fvets.2025.1636738
Su Been Park, Gun Hee Cho, Young Eun Park, Hyang Sook Chun • Toxins
(2023)
Emodin, an emerging mycotoxin, is known to be hepatotoxic, but its mechanism remains unclear. We hypothesized that emodin could induce endoplasmic reticulum (ER) stress through the inositol-requiring enzyme 1 alpha (IRE1α)–X-box-binding pro...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/toxins15070455
Huifang Lian, Huifang Lian, Huifang Lian, Huifang Lian et al. • Frontiers in Medicine
(2022)
PurposeFungal keratitis is a sight-threatening corneal infection caused by fungal pathogens, and the pathogenic mechanisms have not been fully elucidated. The aim of this study was to determine whether NOD-like receptor family pyrin domain ...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmed.2022.845129
Michelle S. Liberio, Martin C. Sadowski, Colleen C. Nelson, Rohan A. Davis • Marine Drugs
(2014)
Ascidians are marine invertebrates that have been a source of numerous cytotoxic compounds. Of the first six marine-derived drugs that made anticancer clinical trials, three originated from ascidian specimens. In order to identify new anti-...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/md12105222
Susana Santos, Tiago Ferreira, José Almeida, Maria J. Pires et al. • Marine Drugs
(2019)
Some diet profiles are associated with the risk of developing cancer; however, some nutrients show protective effects. Porphyra umbilicalis is widely consumed, having a balanced nutritional profile; however, its potential for cancer chemopr...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/md17110615
Lufei Chen, Chaoxian Dai, Zhenfang Wu, Yuhan Lin et al. • Journal of Xenobiotics
(2026)
Accumulating epidemiological evidence links ambient PM2.5 exposure to elevated Parkinson’s disease (PD) risk, yet the neurotoxicity triggered by PM2.5 multi-pollutant mixtures under real co-exposure scenarios remains insufficiently elucidat...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/jox16060184
Sarah Al-Nasser, Maha Hamadien Abdulla, Noura Alhassan, Mansoor-Ali Vaali-Mohammed et al. • Medicina
(2024)
Background and Objectives: Colorectal cancer (CRC) remains a major global health issue. Although chemotherapy is the first-line treatment, its effectiveness is limited due to drug resistance developed in CRC. To overcome resistance and impr...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/medicina60091379
Das S, Satapathy BS, Pattnaik G, Pattanaik S et al. • International Journal of Nanomedicine
(2025)
Shubhashree Das,1 Bhabani Sankar Satapathy,2 Gurudutta Pattnaik,1 Sovan Pattanaik,3 Yahya Alhamhoom,4 Mohamed Rahamathulla,4 Mohammed Muqtader Ahmed,5 Ismail Pasha6 1Department of Pharmaceutics, School of Pharmacy and Life Sciences, Centuri...
DOAJ
Open Access (DOAJ)