Reset
Showing 20 of 192 academic articles

Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway

Qian Qin, Zhiyan Shan, Lei Xing, Yutong Jiang et al. • Journal of Translational Medicine (2024)

Abstract Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-deri...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-024-05257-w

Correcting palindromes in long reads after whole-genome amplification

Sven Warris, Elio Schijlen, Henri van de Geest, Rahulsimham Vegesna et al. • BMC Genomics (2018)

Abstract Background Next-generation sequencing requires sufficient DNA to be available. If limited, whole-genome amplification is applied to generate additional amounts of DNA. Such amplification often results in many chimeric DNA fragments...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12864-018-5164-1

miR-130a-3p Exacerbates Sepsis-Induced Cardiac Dysfunction by Promoting Inflammation and Targeting PDK4

Jinyu Liu, Xiaowei Yuan, Wei Chen, Dongqin Shen • Clinical and Applied Thrombosis/Hemostasis (2026)

Background Sepsis is frequently complicated by systemic inflammatory injury and cardiac dysfunction, which serve as risk factors of adverse clinical outcomes and increased mortality risk. To clarify the function of miR-130a-3p in sepsis dia...

DOAJ Open Access (DOAJ) DOI: 10.1177/10760296261468449

Multi-Cohort Transcriptomics Combined with Mendelian Randomization Identifies PPARGC1A, NAAA and GIPC2 as NLRP3 Inflammasome-Related Key Genes in Ulcerative Colitis

Cheng J, Huang Y • Journal of Inflammation Research (2026)

Jian Cheng, Yangfeng Huang Department of Traditional Chinese Medicine, Sichuan Provincial People’s Hospital, School of Medicine,University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of ChinaCorrespond...

DOAJ Open Access (DOAJ)

Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline

Mahdie Kian, Elham Hosseini, Tooba Abdizadeh, Taimour Langaee et al. • EXCLI Journal : Experimental and Clinical Sciences (2022)

Polycystic ovary syndrome (PCOS) is the most common cause of women’s infertility. Some inflammatory pathways play a pivotal role in the pathogenesis of PCOS. This study aimed to investigate the possible beneficial effects of minocycline on ...

DOAJ Open Access (DOAJ) DOI: 10.17179/excli2021-4534

Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study

Chung-woo Lee, Joo Kyung Lee, Yeon Joo Choi, Hyunjin Kim et al. • Scientific Reports (2022)

Abstract Revascularization procedures, including percutaneous coronary intervention (PCI), for coronary artery disease (CAD) are increasingly performed in Korea. However, studies on blood pressure control targets in these patients remain in...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-06627-4

Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types

Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li et al. • Molecular Cancer (2021)

Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-021-01362-2

Melatonin Regulates Lipid Metabolism in Porcine Cumulus–Oocyte Complexes via the Melatonin Receptor 2

Jun-Xue Jin, Jing-Tao Sun, Chao-Qian Jiang, Hong-Di Cui et al. • Antioxidants (2022)

Previous studies suggest that the inclusion of melatonin (MTn) in in vitro maturation protocols improves the developmental competence of oocytes by scavenging reactive oxygen species (ROS). However, the molecular mechanisms integrating mela...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox11040687

Impact of internal remittance on households' use of bank services: evidence from Vietnam

Thu Thi Hoai Nguyen, Hung Manh Le, Le Quoc Hoi, Hang Thu Pham • Journal of Economics Finance and Administrative Science (2022)

Purpose – This study estimates impact of remittances from internal migration on households' use of bank services in Vietnam. Design/methodology/approach – This study uses data from the Vietnam Household Living Standards Survey and the two-s...

DOAJ Open Access (DOAJ) DOI: 10.1108/JEFAS-05-2021-0074

An agent-based modeling framework for the design of a dynamic closed-loop supply chain network

Ayşegül Bozdoğan, Latife Görkemli Aykut, Neslihan Demirel • Complex & Intelligent Systems (2022)

Abstract The supply chain is a dynamic and uncertain system consisting of material, information, and fund flows between different organizations, from the acquisition of the raw materials to the delivery of the finished products to the end c...

DOAJ Open Access (DOAJ) DOI: 10.1007/s40747-022-00780-z

Women’s Water Access Is Associated With Measures of Empowerment and Social Support: A Cross-sectional Study in Sub-Saharan Africa

Hiliary Monteith, Davod Ahmadi, Kate Sinclair, Narges Ebadi et al. • Journal of Rural and Community Development (2020)

Water access is an important global issue that impacts health and wellbeing and has been recognized by the United Nations as a significant area for improvement. Despite some global improvements from the Millennium Development Goals (MDGs) t...

DOAJ Open Access (DOAJ)

Study of mutations in IDH1 and IDH2 genes in a sample of gliomas from Colombian population

Orlando Ricaurte, Karina Neita, Danyela Valero, Jenny Ortega-Rojas et al. • Biomédica: revista del Instituto Nacional de Salud (2018)

Introduction: Gliomas are the most common primary tumors of the central nervous system and, according to their malignancy, they are graded from I to IV. Recent studies have found that there is an association between gliomas and mutations in...

DOAJ Open Access (DOAJ) DOI: 10.7705/biomedica.v38i0.3708

Epoetin zeta in the management of anemia associated with chronic kidney disease, differential pharmacology and clinical utility

Davis-Ajami ML, Wu J, Downton K, Ludeman E et al. • Biologics: Targets & Therapy (2014)

Mary Lynn Davis-Ajami,1 Jun Wu,2 Katherine Downton,3 Emilie Ludeman,3 Virginia Noxon4 1Organizational Systems and Adult Health, University of Maryland School of Nursing, Baltimore, MD, USA; 2South Carolina College of Pharmacy, University of...

DOAJ Open Access (DOAJ)

In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity

Andre Luis Dias Araujo Mazzari, Mariella Guimarães Lacerda, Flora Aparecida Milton, Flora Aparecida Milton et al. • Frontiers in Pharmacology (2022)

Many medicinal plants species from European -such as Artemisia absinthium, Equisetum arvense, Lamium album, Malva sylvestris, Morus nigra, Passiflora incarnata, Frangula purshiana, and Salix alba- as well as Latin American traditions -such ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2022.826395

Fumaric acid regulates morphine tolerance in bone cancer pain through spinal MrgC receptor modulation

Sijie Liu, Minghao Tang, Jing Zhao, Lulu Zhang et al. • Pakistan Journal of Pharmaceutical Sciences (2026)

Background: Bone cancer pain (BCP) represents a debilitating complication that profoundly impacts patient quality of life and predisposes to psychological comorbidities, including depression and anxiety. Objectives: To investigate the effec...

DOAJ Open Access (DOAJ) DOI: 10.36721/PJPS.2026.39.8.233.1

Pertanggungjawaban Korporasi atas Kelalaian Karyawan Bank di Indonesia

Purnomo Purnomo, Kadi Sukarna, Muhammad Junaidi, Kukuh Sudarmanto et al. • Jurnal USM Law Review (2026)

This study aims to analyze corporate legal liability for customer losses caused by bank employees’ negligence and the legal consequences imposed on employees within the Indonesian legal system. The central issue lies in the lack of legal ce...

DOAJ Open Access (DOAJ) DOI: 10.26623/julr.v9i3.12709