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Association of androgen receptor and tumour-infiltrating lymphocytes with bone recurrence in triple-negative breast cancer

Petra Ilenič, Ajda Herman, Erik Langerholc, Barbara Gazić et al. • Journal of Bone Oncology (2024)

Background: As compared to endocrine responsive breast cancer bone is less frequent site of distant recurrence in triple-negative breast cancer (TNBC). A biomarker which predicts bone recurrence would allow a more personalized treatment app...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jbo.2023.100518

Artificial intelligence–aided diagnosis model for acute respiratory distress syndrome combining clinical data and chest radiographs

Kai-Chih Pai, Wen-Cheng Chao, Yu-Len Huang, Ruey-Kai Sheu et al. • Digital Health (2022)

Objective The aim of this study was to develop an artificial intelligence–based model to detect the presence of acute respiratory distress syndrome (ARDS) using clinical data and chest X-ray (CXR) data. Method The transfer learning method w...

DOAJ Open Access (DOAJ) DOI: 10.1177/20552076221120317

Development and validation of an interpretable machine learning model for predicting the risk of coronary heart disease risk in diabetes mellitus patients: a dual-center retrospective study

Ye Kuang, Yan Yu, Jing Li, Chuanmei Peng et al. • BMC Medical Informatics and Decision Making (2026)

Abstract Background Diabetes mellitus (DM) combined with coronary heart disease (CHD) significantly increases the risk of cardiovascular events with a greater mortality rate. Therefore, establishing a predictive model can help DM patients r...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12911-026-03461-w

Integrating machine learning algorithms and explainable artificial intelligence approach for predicting patient unpunctuality in psychiatric clinics

Alireza Kasaie, Suchithra Rajendran • Healthcare Analytics (2023)

This study addresses patient unpunctuality, a major concern affecting patient waiting time, resource utilization, and quality of care. We develop and compare four machine learning models, including multinomial logistic regression, decision ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.health.2023.100242

Functional neuroimaging of visuospatial working memory tasks enables accurate detection of attention deficit and hyperactivity disorder

Rubi Hammer, Gillian E. Cooke, Mark A. Stein, James R. Booth • NeuroImage: Clinical (2015)

Finding neurobiological markers for neurodevelopmental disorders, such as attention deficit and hyperactivity disorder (ADHD), is a major objective of clinicians and neuroscientists. We examined if functional Magnetic Resonance Imaging (fMR...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2015.08.015

Health-related quality of life in Chinese population with non-alcoholic fatty liver disease: a national multicenter survey

Rui Huang, Jian-Gao Fan, Jun-Ping Shi, Yi-Min Mao et al. • Health and Quality of Life Outcomes (2021)

Abstract Background Health Related Quality of Life (HRQL) is a multi-dimensional construct that can comprehensively evaluate the patient’s health status, including physical, emotional, mental and social well-being. In this study, we aimed t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12955-021-01778-w

The influence of patient characteristics on the alarm rate in intensive care units: a retrospective cohort study

Zeena-Carola Sinno, Denys Shay, Jochen Kruppa, Sophie A.I. Klopfenstein et al. • Scientific Reports (2022)

Abstract Intensive care units (ICU) are often overflooded with alarms from monitoring devices which constitutes a hazard to both staff and patients. To date, the suggested solutions to excessive monitoring alarms have remained on a research...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-26261-4

Data describing the poor outcome associated with a breast cancer diagnosis in the post-weaning period

Hanne Lefrère, Giuseppe Floris, Marjanka K. Schmidt, Patrick Neven et al. • Data in Brief (2021)

Postpartum breast cancer (PPBC) - which according to new data, can extend to 5–10 years after the birth - are estimated to represent 35–55% of all cases of breast cancer in women younger than 45 years. Increasing clinical evidence indicates...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2021.107354

Digital Exclusion and Cognitive Function in Elderly Populations in Developing Countries: Insights Derived From 2 Longitudinal Cohort Studies

Sainan Duan, Dongxu Chen, Jinping Wang, Mohammed Sharooq Paramboor et al. • Journal of Medical Internet Research (2024)

BackgroundCognition disorders not only lead to adverse health consequences but also contribute to a range of socioeconomic challenges and diminished capacity for performing routine daily activities. In the digital era, understanding the imp...

DOAJ Open Access (DOAJ) DOI: 10.2196/56636

Predictors of community acquired childhood pneumonia among 2–59 months old children in the Amhara Region, Ethiopia

Muluken Genetu Chanie, Mequannent Sharew Melaku, Melaku Yalew, Mastewal Arefaynie et al. • BMC Pulmonary Medicine (2021)

Abstract Background Worldwide, pneumonia is the third leading cause of death in under 5 years children. Ethiopia is ranked 4th out of 15 countries having the highest burdens of the death rate among under-five children due to pneumonia. Rega...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12890-021-01548-w

Referrals and utilization of diabetes self-management education and support (DSMES) among patients with type 1 and type 2 diabetes at a regional medical center in Kentucky

Omer Atac, George C. Bryant, William B. Burrows, Kory R. Heier et al. • BMC Public Health (2025)

Abstract Background The goal of this study was to examine referral and attendance patterns for diabetes self-management education and support (DSMES) among patients with both type 1 (T1D) and type 2 diabetes (T2D) at a regional medical cent...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-025-25014-y

Association of maternal metabolic risk factors with offspring body mass index (BMI) trajectories in early childhood: a retrospective cohort study

Wei Song, Xiao Yang, Liu Yang, Yan Ren et al. • BMJ Open (2025)

Objective This study aimed to identify body mass index (BMI) growth trajectories from birth to 24 months of age and examine the independent and additive effects of four maternal metabolic risk factors, namely prepregnancy BMI, the rate of g...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2024-088641

Abnormal cervical cancer screening results among US Veteran and non-Veteran participants in the National Health Interview Survey (NHIS)

Elisheva R. Danan, Claire Than, Neetu Chawla, Katherine J. Hoggatt et al. • Preventive Medicine Reports (2023)

Female Veterans report cervical cancer risk factors at higher rates than non-Veterans. Using data from the National Health Interview Survey (NHIS), we tested whether Veterans with a recent cervical cancer screening test were more likely tha...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.pmedr.2023.102472

Prevalence of Constipation in Elderly and Its Association With Dementia and Mild Cognitive Impairment: A Cross-Sectional Study

Fei Wang, Fei Wang, Min Fei, Min Fei et al. • Frontiers in Neuroscience (2022)

BackgroundConstipation and dementia have similar epidemiological characteristics. Changes in intestinal flora and characteristics of the brain-gut axis play roles in the pathogeneses of the two diseases, suggesting that there may be a close...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2021.821654

Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome

Antonio Musolino, Marco Roversi, Mariateresa Romaniello, Vittorio Scoppola et al. • Vaccine: X (2025)

Introduction: Pneumococcal vaccination has significantly decreased the burden of invasive pneumococcal disease in the general population, however studies on effectiveness in Down syndrome (DS) are heterogeneous. In this cross-sectional stud...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jvacx.2025.100744

Reimbursement Legislations and Decision Making for Orphan Drugs in Central and Eastern European Countries

Krzysztof Piotr Malinowski, Paweł Kawalec, Wojciech Trąbka, Marcin Czech et al. • Frontiers in Pharmacology (2019)

BackgroundReimbursement policies influence access of patients to orphan drugs in the European countries.ObjectivesTo provide a comprehensive description of orphan drug reimbursement policies and to assess reimbursement decision-making proce...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2019.00487

Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study

Md. Jamal Hossain, Foyez Ahmmed, Md. Robin Khan, Parisa Tamannur Rashid et al. • Frontiers in Nutrition (2022)

ObjectivesThis current study aims to assess the prevalence and factors associated with body mass index (BMI), dietary patterns, and the extent of physical activities among university students following the prolonged coronavirus disease 2019...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2022.873105

Maternal dietary fiber intake during pregnancy and child development: the Japan Environment and Children's Study

Kunio Miyake, Sayaka Horiuchi, Ryoji Shinohara, Megumi Kushima et al. • Frontiers in Nutrition (2023)

BackgroundAnimal studies have shown that maternal low-fiber diets during pregnancy may impair brain development and function in offspring, but this has not been validated by epidemiological studies. The aim of this study was to investigate ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2023.1203669

Development of a Scoring System to Predict the Treatment Success for Nonoperative Management of Peptic Ulcer Perforation: A Secondary Data Analysis of PPAP Study

Kei Ito, Akira Endo, Hiromasa Hoshi, Koji Ito et al. • Annals of Gastroenterological Surgery (2026)

ABSTRACT Background Although surgical treatment is the primary measure for patients with perforated peptic ulcer (PPU), nonoperative management (NOM) has become a common alternative. However, risk score models predicting the success of NOM ...

DOAJ Open Access (DOAJ) DOI: 10.1002/ags3.70074