Academic Articles & Research Papers

Characterization of swine-origin H1N1 canine influenza viruses

Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province of China. This host switch was fo...

A 1-minute blood test detects decreased immune function and increased clinical risk in COVID-19 patients

Abstract Upon infection with SARS-CoV-2, the virus that causes COVID-19, most people will develop no or mild symptoms. However, a small percentage of the population will become severely ill, and some will succumb to death. The clinical seve...

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS>0) is often missing or inaccurate in re...

Effects of an infant formula containing a whey protein concentrate on feeding tolerance and markers of intestinal immune defense in Chinese infants

Abstract Background Human milk (HM) bioactive components can have immune modulatory functions, impact the gut microbiome, and may result in functional benefits when added to infant formula (IF). In this single-arm, prospective, intervention...

Alpha-Synuclein Induced Immune Cells Activation and Associated Therapy in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disorder closely related to immunity. An important aspect of the pathogenesis of PD is the interaction between α-synuclein and a series of immune cells. Studies have shown that accumulation of...

Fipronil disturbs the antigen-specific immune responses and GABAergic gene expression in the ovalbumin-immunized BALB/c mice

Abstract Background Fipronil (FPN) is a broad-spectrum pesticide and commonly known as low toxicity to vertebrates. However, increasing evidence suggests that exposure to FPN might induce unexpected adverse effects in the liver, reproductiv...

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden. The globally dominant sequence type 239 (ST239) HA-MRSA clone has persiste...

THE METHODOLOGY OF INFORMATION CAPABILITIES ESTIMATION FOR FIBER-OPTICS COMMUNICATION

The method for assessing a channel capacity and productivity of fiber-optic communication line (FOCL) based on the DWDM (Dense Wavelength Division Multiplexing) technology is proposed. The interrelation between noise-immunity factors and in...

Clustered Regularly Interspaced Short Palindromic Repeat/Cas12a Mediated Multiplexable and Portable Detection Platform for GII Genotype Porcine Epidemic Diarrhoea Virus Rapid Diagnosis

Porcine epidemic diarrhoea virus (PEDV) is a member of the genus Alphacoronavirus in the family Coronaviridae. It causes acute watery diarrhoea and vomiting in piglets with high a mortality rate. Currently, the GII genotype, PEDV, possesses...

A review on quantum computing and communication

By the birth of Quantum Physics, many new areas were opened for research and development in the world of science and technology. One such field is Quantum Computing and Communication where there is room for all that was once a dream in the ...

Structural basis of cooperative neutralization of the PldB toxin by immunity proteins in Pseudomonas aeruginosa.

Metal-Ligand Coordination Nanomaterials Tailored to the Cancer-Immunity Cycle.

Living standard and access to tetanus toxoid immunization among women in Bangladesh

Abstract Background Although Bangladesh has an impressive track record in the reduction of maternal and child mortality, tetanus, a dreadful disease, impedes the way to achieve Sustainable Development Goal (SDG) in this respect. Sufficient ...

Beyond Herd Immunity Against Strategic Attackers

Herd immunity, one of the most fundamental concepts in network epidemics, occurs when a large fraction of the population of devices is immune against a virus or malware. The few individuals who have not taken countermeasures against the thr...

Antiviral humoral immunity as biomarker and effector in oncolytic adenovirus TILT-123 therapy.

The altered T cell landscape in systemic sclerosis patients is characterized by dysfunctional type 1 immunity.

Cold storage of human precision-cut lung slices in TiProtec preserves cellular composition and transcriptional responses and enables on-demand mechanistic studies

Abstract Background Human precision-cut lung slices (hPCLS) are a unique platform for functional, mechanistic, and drug discovery studies in the field of respiratory research. However, tissue availability, generation, and cultivation time r...

Study of serum Total Immunoglobulin E in Egyptian patients with newly diagnosed colorectal carcinoma

Total immunoglobulin E (IgE) has roles in allergy and anti-parasitic immunity. Recently IgE showed a major role in cancer immune surveillance; an increased risk of solid and blood malignancies has been associated with total IgE deficiency. ...

Invertebrate Ecological Immunology

Ecological immunology is a rapidly expanding field that examines the causes and consequences of variation in immune function in the context of evolution and of ecology. Millions of invertebrate species rely solely on innate immunity, compar...

Wild immunology

In wild populations, individuals are regularly exposed to a wide range of pathogens. In this context, organisms must elicit and regulate effective immune responses to protect their health while avoiding immunopathology. However, most of our...