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Preclinical Characterization of Mobocertinib Highlights the Putative Therapeutic Window of This Novel EGFR Inhibitor to EGFR Exon 20 Insertion Mutations

Pedro E.N.S. Vasconcelos, MS, Ikei S. Kobayashi, MD, PhD, Susumu S. Kobayashi, MD, PhD, Daniel B. Costa, MD, PhD • JTO Clinical and Research Reports (2021)

Introduction: EGFR exon 20 insertion mutations account for 10% of all EGFR mutations and are mostly insensitive to approved EGFR tyrosine kinase inhibitors (EGFR TKIs). Novel EGFR TKIs have been developed or repurposed for these mutants. A ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jtocrr.2020.100105

Ethnomathematical Exploration of Geometric Concepts in Tegowangi Temple Ornaments

Bryant Candra Wijaya, Fanny Rahma Eka Aprianny, Amelia Putri Wahyuni, Jatmiko Jatmiko et al. • Noumerico (2026)

This study explores geometric concepts embedded in the ornaments of Tegowangi Temple through an ethnomathematical perspective. Previous studies on temple-based ethnomathematics have primarily focused on general geometric forms, with limited...

DOAJ Open Access (DOAJ) DOI: 10.33367/jtme.v4i1.8472

Family management risk and protective factors for adolescent substance use in South Africa

Beatrice Wamuyu Muchiri, Monika M. L. dos Santos • Substance Abuse Treatment, Prevention, and Policy (2018)

Abstract Background An increasingly recognised prevention approach for substance use entails a reduction in risk factors, and the enhancement of promotive, or protective factors in individuals and the environment surrounding them during the...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13011-018-0163-4

Acute cognitive effects of interruptions to prolonged sitting with brief standing or physical activity breaks: a systematic review and three-level meta-analysis

Mingnan Zhuang, Mingyue Yin, Zongnan Liu, Ningkun Xiao et al. • International Journal of Behavioral Nutrition and Physical Activity (2026)

Abstract Background Prolonged sitting is strongly associated with impaired cognitive function. Although traditional exercise interventions have been shown to improve cognitive outcomes, their implementation is often limited by practical con...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12966-026-01953-6

Sex-Related Differences in Regional Homogeneity and Intolerance of Uncertainty in Obsessive-Compulsive Disorder: A Resting-State fMRI Study

Wang A, Zhao S, Guo Q, Wu J et al. • Neuropsychiatric Disease and Treatment (2026)

Anzhen Wang,1,2 Shuai Zhao,1 Qihui Guo,3,4 Jinling Wu,1 Wenmei Fang,1 Shuang Zheng,1 Chunyan Zhu,2,5,6 Xiangyang Zhang1,3,41Affiliated Psychological Hospital of Anhui Medical University, Anhui Medical University, Hefei, People’s Republic of...

DOAJ Open Access (DOAJ)

Yes! Kissing Too… The Child Would Not Be Hurt in Any Way: Social Constructions of Child Sexual Abuse in the Ga Community in Ghana

Ummu Markwei • Qualitative Sociology Review (2019)

The United Nations Convention on the Rights of the Child obligates nations to protect children from all forms of abuse including sexual. However, child sexual abuse is a complex phenomenon which is difficult to understand as a result of cul...

DOAJ Open Access (DOAJ) DOI: 10.18778/1733-8077.15.3.06

Barriers and opportunities for clinical trials in Bahrain: a qualitative study of key opinion leaders

Jamil Ahmed, Angeleena Esther, Hussein AlHafnawi, Mohamed Hany Shehata et al. • BMJ Open (2026)

Background and objectives Clinical trials are essential for advancing scientific knowledge and improving patient outcomes. In the last decade, Bahrain has made notable progress in healthcare. However, clinical trial participation from the r...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2026-117241

The elderly and urban mobility: cost sensitivity of elderly people in the “oldest” Italian city

Claudia Burlando, Enrico Musso, Luca Persico • European Spatial Research and Policy (2022)

The world is facing a series of changes that will modify the way we envisage transport planning in our cities. Demographic ageing as a consequence of higher life expectancy and lower fertility rates is a world-wide phenomenon. While ageing ...

DOAJ Open Access (DOAJ) DOI: 10.18778/1231-1952.29.1.05

Trait impulsivity prospectively predicts lower methadone treatment retention: moderation by pain catastrophizing

Annabelle M. Belcher, Kristen R. Hamilton-Moseley, Ebonie Massey, Mark Yoon et al. • Addiction Science & Clinical Practice (2026)

Abstract Background Empirical evidence supports the use of methadone as the standard of care for opioid use disorder. However, low retention in methadone treatment is one of the largest impediments to treatment success. Although several psy...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13722-026-00699-7

Discriminative efficacy and comparative analysis of functional performance tests for lower-limb injuries in Chinese elite female basketball athletes: a pilot cross-sectional study

Lu Zhang, Xingjian Xiong, Muxi Zhang, Enming Zhang • BMC Musculoskeletal Disorders (2025)

Abstract Background Elite female basketball players experience a high incidence of lower-limb injuries, yet evidence remains limited regarding the applicability of common functional performance tests in this population. This study aimed (1)...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12891-025-09398-x

Engaging Nurses in Effective Cost of Care Conversations to Address Cancer-Related Financial Toxicity: Results from an Exploratory Survey

Jean S. Edward, Amanda Thaxton Wiggins, Louis G. Baser, Haafsah Fariduddin et al. • Current Oncology (2025)

Few evidence-based trainings exist on how to equip healthcare providers, particularly nurses, with the skills to engage in cost of care conversations with patients/caregivers to mitigate the impact of cancer-related financial toxicity. This...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol32010033

Branding cities, regions and countries: the roadmap of place brand equity

Fabiana Gondim Mariutti, Janaina de Moura Engracia Giraldi • RAUSP Management Journal (2021)

Purpose – The purpose of this paper is two-fold: to expand the understanding of brand equity for places (e.g. countries, regions or cities) and propose two frameworks to increase its value. Design/methodology/approach – By interviewing inte...

DOAJ Open Access (DOAJ) DOI: 10.1108/RAUSP-06-2020-0131

Consumers' Perception of Urban Farming—An Exploratory Study

Carola Grebitus, Lauren Chenarides, Rebecca Muenich, Alex Mahalov • Frontiers in Sustainable Food Systems (2020)

Urban agriculture offers the opportunity to provide fresh, local food to urban communities. However, urban agriculture can only be successfully embedded in urban areas if consumers perceive urban farming positively and accept urban farms in...

DOAJ Open Access (DOAJ) DOI: 10.3389/fsufs.2020.00079

Revistes usades pels investigadors de ciències de la informació del Brasil per publicar i la seva visibilitat en les bases de dades Web of Science i Scopus

Pinheiro, Liliana Vierira, Da Silva, Edna Lúcia, Rodríguez, Rosangela Schwarz • BiD: Textos Universitaris de Biblioteconomia i Documentació (2014)

Introducció: la producció és part essencial de l'activitat científica i la seva visibilitat és un indicador per avaluar la ciència. Les revistes científiques s'han transformat i el moviment d'accés obert ha impulsat canvis en el model de co...

DOAJ Open Access (DOAJ) DOI: 10.1344/BiD2014.32.16

Approaches to Innovation Process Assessment: Complex Results from an Exploratory Investigation

Ondrej Zizlavsky • International Journal of Engineering Business Management (2015)

Managing innovation is vital for many enterprises to survive in a competitive and dynamic environment. Thus, decision-makers have always been involved in the challenge of finding the right performance measures for the innovation process. Th...

DOAJ Open Access (DOAJ) DOI: 10.5772/62052

Context presentation and native conversation structure in large language model responses to escalating suicide risk: a controlled multimodel evaluation

Jueqiao Liu, Jueqiao Liu, Xiaoyi Chen, Jun Cai et al. • Frontiers in Psychiatry (2026)

BackgroundLarge language models are increasingly used for informal mental health support, yet their safety during escalating suicide-risk conversations may depend on how prior information is presented. Native multi-turn conversations and re...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2026.1962098

GIS-Based Geothermal Favorability Mapping and Geological Consistency Assessment in the Lower Kura Basin

Allahverdi Tagiyev, Elmir Karagozov, Mehriban Ismayilova, Lala Abdullayeva et al. • Energies (2026)

The Lower Kura Basin is a tectonically active sedimentary region of Azerbaijan where geological and hydrogeological conditions may favor geothermal fluid circulation. This study develops a Geographic Information Systems (GIS)-based multi-cr...

DOAJ Open Access (DOAJ) DOI: 10.3390/en19174061

Bridging the Smart Tourism Skills Gap: Industry Perspectives on Fourth Industrial Revolution Competencies and Curriculum Transformation in Tourism Education

Fathima Razack, Nalindren Naicker, Reshma Sucheran, Saroj Bala • Tourism and Hospitality (2026)

The aim of this study is to explore the adoption of Smart Tourism (ST) and Fourth Industrial Revolution (4IR) skills demanded by the tourism industry, graduate preparedness, and curriculum alignment in accommodation establishments in KwaZul...

DOAJ Open Access (DOAJ) DOI: 10.3390/tourhosp7090290