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Tissue-specific responses of antioxidant pathways to poor hygiene conditions in growing pigs divergently selected for feed efficiency

K. Sierżant, M-H. Perruchot, E. Merlot, N. Le Floc’h et al. • BMC Veterinary Research (2019)

Abstract Background Poor hygiene of housing induces a systemic inflammatory response. Because inflammation and oxidative stress are processes that can sustain each other, the ways pigs are able to activate their antioxidant defenses are cri...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12917-019-2107-2

Comparative Evaluation of the Antioxidant and Immunomodulatory Activities of Carrot (<i>Daucus carota</i> L.) Aerial Parts and Roots Using Different Extraction Methods

Sung-Sook Choi, Jae-Eun Lee, Hyo-Jun Lee, Kyung-Ae Lee • Foods (2025)

Carrot (Daucus carota L.) is a widely consumed root vegetable, yet its aerial parts, including leaves and stems, are typically discarded as agricultural by-products, despite their potential biological value. This study comparatively evaluat...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods14233993

Optimization of cationic nanoparticles stabilized by poloxamer 188: A potential approach for improving the biological activity of Aloe perryi

Tahany Saleh Aldayel, Mohamed M. Badran, Abdullah H. Alomrani, Nora A. AlFaris et al. • Heliyon (2023)

Aloe perryi (AP) has gained considerable interest as a medicinal herb in various biological applications due to its rich phytochemical composition. However, the therapeutic benefits of AP could be potentiated by utilizing nanotechnology. Mo...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2023.e22691

Beneficial Effects of Pomegranate Peel Extract and Probiotics on Pre-adipocyte Differentiation

Valeria Sorrenti, Cinzia Lucia Randazzo, Cinzia Caggia, Gabriele Ballistreri et al. • Frontiers in Microbiology (2019)

The beneficial effects of pomegranate are due to the ellagitannins and anthocyanins content, which are protective toward a wide variety of diseases including inflammatory diseases. Many investigators have reported that pomegranate waste (pe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2019.00660

Incubation of semen with human follicular fluid improves the antioxidant status and quality of spermatozoa after freezing–thawing

Monireh Mahmoodi, Elham Shojafar, Maryam Dastjani-Farahani • Reproduction and Fertility (2025)

The sperm freezing–thawing procedure is the most commonly used technique in clinics to preserve male fertility before any pathological destruction of the testis. Therefore, most studies are currently focused on optimizing this method to ach...

DOAJ Open Access (DOAJ) DOI: 10.1530/RAF-24-0056

Transcriptomes Suggest That Pinniped and Cetacean Brains Have a High Capacity for Aerobic Metabolism While Reducing Energy-Intensive Processes Such as Synaptic Transmission

Cornelia Geßner, Alena Krüger, Lars P. Folkow, Wilfrid Fehrle et al. • Frontiers in Molecular Neuroscience (2022)

The mammalian brain is characterized by high energy expenditure and small energy reserves, making it dependent on continuous vascular oxygen and nutritional supply. The brain is therefore extremely vulnerable to hypoxia. While neurons of mo...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnmol.2022.877349

Developing a Rational, Optimized Product of Centella asiatica for Examination in Clinical Trials: Real World Challenges

Kirsten M. Wright, Janis McFerrin, Armando Alcázar Magaña, Armando Alcázar Magaña et al. • Frontiers in Nutrition (2022)

Botanical products are frequently sold as dietary supplements and their use by the public is increasing in popularity. However, scientific evaluation of their medicinal benefits presents unique challenges due to their chemical complexity, i...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2021.799137

Dietary antioxidants and lifespan: Relevance of environmental conditions, diet, and genotype of experimental models

Alfonso Varela-López, José M. Romero-Márquez, María D. Navarro-Hortal, César L. Ramirez-Tortosa et al. • Experimental Gerontology (2023)

The rise of life expectancy in current societies is not accompanied, to date, by a similar increase in healthspan, which represents a great socio-economic problem. It has been suggested that aging can be manipulated and then, the onset of a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2023.112221

<i>Sechium edule</i> var. <i>nigrum spinosum</i> (Chayote) Increases the mRNA Expression of Genes Encoding Sirtuins in Older Adults with Type 2 Diabetes Mellitus

Graciela Gavia-García, David Hernández-Álvarez, Taide Laurita Arista-Ugalde, Itzen Aguiñiga-Sánchez et al. • Molecules (2026)

Consumption of Sechium edule var. nigrum spinosum has antioxidant and hypoglycemic effects. Regarding the former, certain signaling pathways that influence these effects have already been proposed; however, the underlying molecular mechanis...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules31071182

Emodin inhibits Newcastle disease virus replication via regulating the phosphorylation levels of eEF2K/eEF2 and targeting viral N protein to reduce viral protein production

Wenjie Wu, Rongjing Xia, Si Ma, Zenglei Hu et al. • Poultry Science (2026)

Newcastle disease (ND) caused by Newcastle disease virus (NDV) infection is a highly contagious avian disease that causes substantial threat to the global poultry industry. Emodin (EMO), a member of the free anthraquinone compounds derived ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.psj.2026.107180 PMC: PMC13265661

Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies

Atefeh Varmazyari, Ali Taghizadehghalehjoughi, Cigdem Sevim, Ozlem Baris et al. • Toxicology Reports (2020)

Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nano...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2020.04.011

Green Synthesized Zinc Oxide Nanoparticles Using <i>Moringa olifera</i> Ethanolic Extract Lessens Acrylamide-Induced Testicular Damage, Apoptosis, and Steroidogenesis-Related Gene Dysregulation in Adult Rats

Gomaa Mostafa-Hedeab, Amany Behairy, Yasmina M. Abd-Elhakim, Amany Abdel-Rahman Mohamed et al. • Antioxidants (2023)

This study assessed the possible protective role of green synthesized zinc oxide nanoparticles using Moringa olifera leaf extract (MO-ZNPs) in acrylamide (ACR)-induced reproductive dysfunctions in male rats. ACR (20 mg/kg b.wt/day) and/or M...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox12020361

Impact of <i>Chlorella vulgaris</i> Bioremediation and Selenium on Genotoxicity, Nephrotoxicity and Oxidative/Antioxidant Imbalance Induced by Polystyrene Nanoplastics in African Catfish (<i>Clarias gariepinus</i>)

Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes (2024)

Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...

DOAJ Open Access (DOAJ) DOI: 10.3390/fishes9020076

Impact of Pressurized Liquid Extraction and pH on Protein Yield, Changes in Molecular Size Distribution and Antioxidant Compounds Recovery from Spirulina

Jianjun Zhou, Min Wang, Celia Carrillo, Zhenzhou Zhu et al. • Foods (2021)

The research aims to extract nutrients and bioactive compounds from spirulina using a non-toxic, environmentally friendly and efficient method—Pressurized Liquid Extraction (PLE). In this work, Response Surface Methodology (RSM)–Central Com...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods10092153

Methyl Jasmonate and Zinc Sulfate Induce Secondary Metabolism and Phenolic Acid Biosynthesis in Barley Seedlings

Xin Tian, Renjiao Zhang, Zhengfei Yang, Weiming Fang • Plants (2024)

This study aimed to reveal the impact of MeJA and ZnSO4 treatments on the physiological metabolism of barley seedlings and the content of phenolic acid. The results showed that MeJA (100 μM) and ZnSO4 (4 mM) treatments effectively increased...

DOAJ Open Access (DOAJ) DOI: 10.3390/plants13111512

Hermetic effect of Moringa oleifera leaf extract mitigates salinity stress in maize by modulating photosynthetic efficiency, and antioxidant activities

MUNEEBA, Abdul KHALIQ, Faran MUHAMMAD, Haroon SHAHZAD et al. • Notulae Botanicae Horti Agrobotanici Cluj-Napoca (2024)

Salinity poses a significant constraint to cereal productivity particularly in arid and semiarid regions. The application of allelochemical has shown promising results in mitigating the intensity of abiotic stresses. A pot experiment was co...

DOAJ Open Access (DOAJ) DOI: 10.15835/nbha52313862

Optimization of lactic fermentation parameters of sugar beet (Beta vulgaris L.) puree with Lactobacillus plantarum and Lactobacillus casei

S. Khalajian, N. Mooraki, M. Honarvar, A. Akhavan Sepahi • Applied Food Research (2026)

This research investigates the lactic fermentation process of sugar beet (Beta vulgaris L.) puree with the aim of creating a functional probiotic product. The focus is on optimizing fermentation conditions to enhance health benefits, thereb...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.afres.2026.101754

Anti-inflammatory activity of two varieties of pumpkin seed oil in an adjuvant arthritis model in rats

S. Y. Al-Okbi, D. A. Mohamed, E. Kandil, M. A. Abo-Zeid et al. • Grasas y Aceites (2017)

The aim of the present research was to evaluate the anti-inflammatory activity of pumpkin seed oils (PSOs) of an Egyptian and European variety, in a rat model of adjuvant arthritis. Edema thickness, plasma tumor necrosis factor-α (TNF-α) an...

DOAJ Open Access (DOAJ) DOI: 10.3989/gya.0796161

Natural Polyphenols for the Preservation of Meat and Dairy Products

Hammad Ullah, Yaseen Hussain, Cristina Santarcangelo, Alessandra Baldi et al. • Molecules (2022)

Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, sa...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules27061906