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Rare genetic diseases associated with G-quadruplex-induced replication stress

Lauren M. Herr, Swagata Mukhopadhyay, Olivia M. Anderson, Tucker H. Couch et al. • Communications Biology (2026)

Abstract DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary structures that present a substant...

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-026-09966-4

Soft x-ray high-harmonic generation in an anti-resonant hollow core fiber driven by a 3 μm ultrafast laser

D. Morrill, W. Hettel, D. Carlson, B. Shearer et al. • APL Photonics (2025)

High-harmonic upconversion driven by a mid-infrared femtosecond laser can generate coherent soft x-ray beams in a tabletop-scale setup. Here, we report on a compact ytterbium-pumped optical parametric chirped pulse amplifier (OPCPA) laser s...

DOAJ Open Access (DOAJ) DOI: 10.1063/5.0292771

Recent progress in tailoring Ni-rich layered oxides via coating and doping strategies for enhanced lithium-ion battery performance

Ha Eun Kang, Seong-Do Kim, Young Soo Yoon, Sang-Jin Lee • Applied Surface Science Advances (2025)

Nickel-rich layered oxide cathodes, typified by compositions such as LiNi₁₋ₓ₋ᵧCoₓMnᵧO₂ (NCM) have garnered significant attention as high-energy-density candidates for next-generation lithium-ion batteries. However, their widespread deployme...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.apsadv.2025.100826

Functionalization of polyoxometalates: towards advanced applications in catalysis and materials science

Anna Proust, René Thouvenot, Pierre Gouzerh • Chemical Communications (2008)

Functionalization via covalent grafting of organic functions allows to tune the redox and acid-base properties, and the solubility of polyoxometalates, to enhance their stability and biological activity and to reduce their toxicity, to faci...

OPENALEX DOI: https://doi.org/10.1039/b715502f

Effect of Ageing on a Novel Cobalt-Free Precipitation-Hardenable Martensitic Alloy Produced by SLM: Mechanical, Tribological and Corrosion Behaviour

Inés Pérez-Gonzalo, Florentino Alvarez-Antolin, Alejandro González-Pociño, Luis Borja Peral-Martinez • Journal of Manufacturing and Materials Processing (2025)

This study investigates the mechanical, tribological, and electrochemical behaviour of a novel precipitation-hardenable martensitic alloy produced by selective laser melting (SLM). The alloy was specifically engineered with an optimised com...

DOAJ Open Access (DOAJ) DOI: 10.3390/jmmp9080261

Extraction of nano-crystalline cellulose for development of aerogel: Structural, morphological and antibacterial analysis

Yash Vishnoi, Alok Kumar Trivedi, M.K. Gupta, Harinder Singh et al. • Heliyon (2024)

In the present decades, nanocellulose has been very popular in the field of nanotechnology and is receiving much attention from researchers because of its advantageous physicochemical properties, high aspect ratio, and high specific strengt...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2023.e23846

Evaluation of resistance modulation in MDR Pseudomonas aeruginosa and Klebsiella pneumoniae using peppermint oil nanoemulsion: integrating antibacterial assays and molecular modeling

Sardar Ali, Firasat Hussain, Tehmeena Nousheen, Kashif Rahim et al. • Frontiers in Microbiology (2025)

IntroductionMultidrug-resistant urinary tract pathogens, primarily Klebsiella pneumoniae and Pseudomonas aeruginosa, represent a significant and growing public health challenge. The overuse of antibiotics has accelerated the development of ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2025.1704938

In vitro antimicrobial and antileishmanial evaluation of green-synthesized ZnO nanoparticles from Cirsium arvense

Yasir Zeb, Asad Ullah, Farhan Ahmad, Bilal Ahmad et al. • Next Nanotechnology (2025)

The emergence of antibiotic-resistant bacterial strains poses a serious public health challenge, urging the need for alternative therapeutic approaches. This study presents, for the first time, the green synthesis of zinc oxide nanoparticle...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nxnano.2025.100281

Highly Sensitive Dopamine Electrochemical Sensor Using Pt Nanoparticles on CNTs/Polypyrrole Nanocomposites

N. I. Nayem, S. Ahmed, Md. A. Rashed, Jahir Ahmed et al. • Electrochemical Science Advances (2026)

ABSTRACT Dopamine (DA) plays a vital role as a neurotransmitter in the central nervous system (CNS), and its accurate quantification is essential for diagnosing neurological disorders. However, selective and sensitive detection of DA in com...

DOAJ Open Access (DOAJ) DOI: 10.1002/elsa.70011

MiR-200c synergizes with trastuzumab-loaded gold nanoparticles to overcome resistance in ovarian cancer cells

Tommaso A. Salamone, Sofia Marotta, Stella Mrmić, Salvatore Raffa et al. • Cancer Nanotechnology (2025)

Abstract Background Trastuzumab (TZ) resistance remains a significant challenge in the treatment of human epidermal growth factor receptor 2 (HER2)-positive epithelial ovarian cancer (EOC), necessitating novel therapeutic strategies to impr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12645-025-00330-5

siRNA Functionalized Lipid Nanoparticles (LNPs) in Management of Diseases

Tutu Kalita, Saba Abbasi Dezfouli, Lalit M. Pandey, Hasan Uludag • Pharmaceutics (2022)

RNAi (RNA interference)-based technology is emerging as a versatile tool which has been widely utilized in the treatment of various diseases. siRNA can alter gene expression by binding to the target mRNA and thereby inhibiting its translati...

DOAJ Open Access (DOAJ) DOI: 10.3390/pharmaceutics14112520

Ultrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization

Maria B. C. de Matos, Roel Deckers, Benjamin van Elburg, Guillaume Lajoinie et al. • Frontiers in Pharmacology (2019)

Mistletoe lectin-1 (ML1) is a nature-derived macromolecular cytotoxin that potently induces apoptosis in target cells. Non-specific cytotoxicity to normal cells is one of the major risks in its clinical application, and we therefore propose...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2019.01463

Tailoring the LiNbO3 coating of Ni-rich cathode materials for stable and high-performance all-solid-state batteries

Seyedhosein Payandeh, Florian Strauss, Andrey Mazilkin, Aleksandr Kondrakov et al. • Nano Research Energy (2022)

The research and development of advanced nanocoatings for high-capacity cathode materials is currently a hot topic in the field of solid-state batteries (SSBs). Protective surface coatings prevent direct contact between the cathode material...

DOAJ Open Access (DOAJ) DOI: 10.26599/NRE.2022.9120016

Archéologie(s) du Paysage et Paysage Archéologique dans la région du Danube inférieur. Histoire d'un projet, méthodologie, et sélection de quelques résultats

PHILIPPE FAJON, BOGDAN SANDRIC, IRINA OBERLÄNDER-TÂRNOVEANU • Cinq Continents (2016)

Landscape Archaeology(ies) and Archaelogical Landscape in the Danubes inferior region. A project history, methodology and a selection of some results. Archaeological practising has changed a lot with the new technologies and new intellec...

DOAJ Open Access (DOAJ)

Agricultural Transformations and Their Influential Factors Revealed by Archaeobotanical Evidence in Holocene Jiangsu Province, Eastern China

Haiming Li, Haiming Li, Haiming Li, Zhen Liu et al. • Frontiers in Earth Science (2021)

The development and adoption of agriculture has been investigated for decades, and remains a central topic within archaeology. However, most previous studies focus on the crop’s domestication centers, leading to gaps in knowledge, particula...

DOAJ Open Access (DOAJ) DOI: 10.3389/feart.2021.661684

On the Anisotropic Velocity Distribution of Newborn Pickup Ions in the Heliosheath

Senbei Du, Merav Opher, Marc Kornbleuth • The Astrophysical Journal Letters (2025)

The evolution of the velocity distribution of pickup ions is crucial for understanding the energetic neutral atom (ENA) fluxes observed by Interstellar Boundary Explorer. Pickup ions in the heliosheath contain two main components: those tra...

DOAJ Open Access (DOAJ) DOI: 10.3847/2041-8213/adbc9a