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Multiple organ failure in the newborn: the point of view of the pathologist

Clara Gerosa, Eleonora Obinu, Daniela Fanni, Rossano Ambu et al. • Journal of Pediatric and Neonatal Individualized Medicine (2014)

One of the most severe events occurring in critically ill patients admitted to a neonatal intensive care unit (NICU) center is represented by the multiple organ failure (MOF), a systemic inflammatory response leading to a progressive organ ...

DOAJ Open Access (DOAJ) DOI: 10.7363/030265

Identification of DDIT4 as a potential prognostic marker associated with chemotherapeutic and immunotherapeutic response in triple-negative breast cancer

Xuanzhao Chen, Zeyan Li, Meihua Liang, Ziyang Zhang et al. • World Journal of Surgical Oncology (2023)

Abstract Background Triple-negative breast cancer (TNBC) is the most heterogenous and aggressive subtype of breast cancer. Chemotherapy remains the standard treatment option for patients with TNBC owing to the unavailability of acceptable t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12957-023-03078-7

Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer

Lilla Bűdi, Dániel Hammer, Rita Varga, Veronika Müller et al. • Pathology and Oncology Research (2025)

ObjectivesSpingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circ...

DOAJ Open Access (DOAJ) DOI: 10.3389/pore.2024.1611929

Preoperative Radiological Findings Prior Endoscopic Dacryocystorhinostomy in Patients with Nasolacrimal Duct Obstruction

Heba Mahmoud Hamdy, Ahmed Abdelrahman • Zagazig University Medical Journal (2025)

Background: Epiphora is a common condition brought on by blockage of the nasolacrimal duct. In order to diagnose and treat these patients, it is critical to evaluate their lacrimal drainage system. This study aimed to identify and analyze t...

DOAJ Open Access (DOAJ) DOI: 10.21608/zumj.2025.395057.4007

Impact of the Age of Cecal Material Transfer Donors on Alzheimer’s Disease Pathology in 5xFAD Mice

Francesco Valeri, Malena dos Santos Guilherme, Fuqian He, Nicolai M. Stoye et al. • Microorganisms (2021)

Alzheimer’s disease is a progressive neurodegenerative disorder affecting around 30 million patients worldwide. The predominant sporadic variant remains enigmatic as the underlying cause has still not been identified. Since efficient therap...

DOAJ Open Access (DOAJ) DOI: 10.3390/microorganisms9122548

Association of SLC6A3 variants with treatment-resistant schizophrenia: a genetic association study of dopamine-related genes in schizophrenia

Masanobu Kogure, Nobuhisa Kanahara, Atsuhiro Miyazawa, Atsuhiro Miyazawa et al. • Frontiers in Psychiatry (2024)

BackgroundMost genetic analyses that have attempted to identify a locus or loci that can distinguish patients with treatment-resistant schizophrenia (TRS) from those who respond to treatment (non-TRS) have failed. However, evidence from mul...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2023.1334335

Genetic impact of non-consanguineous marriages in Saudi Arabia.

Mohammed Alyahya, Taghrid Aloraini, Youseef Al-Harbi, Lamia Alsubaie et al. • Journal of Biochemical and Clinical Genetics (2022)

Background: Physicians and geneticists face challenges in making accurate diagnoses during clinical evaluations; affecting patients and clinicians. The aim of this study was to estimate the hit rate of the non-consanguineous population. Mor...

DOAJ Open Access (DOAJ) DOI: 10.24911/JBCGenetics/183-1664872492

Fungal Communities Associated with Siricid Wood Wasps: Focus on <i>Sirex juvencus</i>, <i>Urocerus gigas</i>, and <i>Tremex fuscicornis</i>

Adas Marčiulynas, Jūratė Lynikienė, Artūras Gedminas, Aistė Povilaitienė et al. • Insects (2024)

We investigated the diversity and occurrence of wood wasps in Lithuania and determined communities of associated fungi. Trapping of wood wasps resulted in three different species, including Sirex juvencus, Urocerus gigas, and Tremex fuscico...

DOAJ Open Access (DOAJ) DOI: 10.3390/insects15010049

miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang et al. • Diagnostic Pathology (2021)

Abstract Background Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of SCD display...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-021-01127-x

Lipofuscin: Wear Pigment or Alarm Signal for Cardiac AlloGraft Vasculopathy?

Anca Otilia Farcas, Mihai Ciprian Stoica, Septimiu Voidazan, Carmen Corina Radu et al. • Diagnostics (2026)

Background: CAV (cardiac allograft vasculopathy) is considered the leading cause of late post-transplant mortality and affects approximately 50% of transplant patients at 10 years post-transplant. Its etiopathogenetic mechanism is considere...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics16152432

Does wet-cupping therapy improve repeated sprint ability, perceived wellness, and rating of perceived exertion in young active males?

Ismail Dergaa, Amine Ghram, Mohamed Romdhani, Amine Souissi et al. • Sports Medicine and Health Science (2024)

Wet-cupping therapy (WCT) is one of the oldest known medical techniques, used as a traditional and complementary therapy with a wide application all around the world for general health. Research on the effects of WCT on sports performance a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.smhs.2023.09.007

Cadmium sulfide-induced toxicity in the cortex and cerebellum: In vitro and in vivo studies

Atefeh Varmazyari, Ali Taghizadehghalehjoughi, Cigdem Sevim, Ozlem Baris et al. • Toxicology Reports (2020)

Living organisms have an innate ability to regulate the synthesis of inorganic materials, such as bones and teeth in humans. Cadmium sulfide (CdS) can be utilized as a quantum dot that functions as a unique light-emitting semiconductor nano...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2020.04.011

Impact of <i>Chlorella vulgaris</i> Bioremediation and Selenium on Genotoxicity, Nephrotoxicity and Oxidative/Antioxidant Imbalance Induced by Polystyrene Nanoplastics in African Catfish (<i>Clarias gariepinus</i>)

Shimaa A. Abdelbaky, Zakaria M. Zaky, Doha Yahia, Mohamed H. Kotob et al. • Fishes (2024)

Contamination of the environment with nano- and microplastic particles exerts a threatening impact on the aquatic ecosystems and sustainable catfish aquaculture. The presence of nanoplastics has been found to have a detrimental impact on bo...

DOAJ Open Access (DOAJ) DOI: 10.3390/fishes9020076

RESTRICION FRAGMENT LENGTH POLYMORPHISM ANALYSIS OF JORDANIAN FIELD STRAINS OF INFECTIOUS BURSAL DISEASE VIRUS

M.Q. AL-NATOUR • Assiut Veterinary Medical Journal (2006)

Reverse transcriptase-polymerase chain reaction/ restriction fragment length polymorphism (RT-PCR/RFLP) techniques were used for the preliminary characterization of Jordanian field strains of Infectious Bursal Disease Viruses (IBDVs). Bursa...

DOAJ Open Access (DOAJ) DOI: 10.21608/avmj.2006.177318

Dietary Supplementation with the Red Seaweed <i>Porphyra umbilicalis</i> Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice

Susana Santos, Tiago Ferreira, José Almeida, Maria J. Pires et al. • Marine Drugs (2019)

Some diet profiles are associated with the risk of developing cancer; however, some nutrients show protective effects. Porphyra umbilicalis is widely consumed, having a balanced nutritional profile; however, its potential for cancer chemopr...

DOAJ Open Access (DOAJ) DOI: 10.3390/md17110615

Coffee Silverskin Phytocompounds as a Novel Anti-Aging Functional Food: A Pharmacoinformatic Approach Combined with In Vitro Study

Clarin Hayes, Fahrul Nurkolis, Dewa Ayu Agus Sri Laksemi, Sanghyun Chung et al. • Molecules (2023)

Coffee became a beverage that was in demand in the world and consequently produced millions of tons of coffee byproducts namely coffee silverskin (CS). Unutilized CS will be waste and cause environmental pollution such as greenhouse gas emi...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28207037

Genital Warts in Women Vaccinated against HPV in Childhood: A Systematic Review

Renata Malheiro, César Magalhães, Cláudia Camila Dias, Acácio Gonçalves Rodrigues et al. • Vaccines (2024)

Human papillomavirus (HPV) is the most prevalent sexually transmitted infection among young women. Notably, more than ten years after the introduction of HPV vaccination programs in Europe, it is essential to review the real-world evidence ...

DOAJ Open Access (DOAJ) DOI: 10.3390/vaccines12050548

Morbimortality in Patients Undergone an Operation for Intestinal Occlusion in General Surgery Service

Alexander Marchena Rodríguez, Reinaldo Jiménez Prendes, Julio César Sarmiento Sánchez • Revista Finlay (2015)

Introduction: the treatment of the intestinal obstruction depends on a premature diagnosis, a skilful and opportune- treatment handling. Objective: characterizing the behavior of the morbimortality for intestinal occlusion at Cienfuegos pro...

DOAJ Open Access (DOAJ)

Preoperative and intraoperative assessment of myometrial invasion in patients with FIGO stage I non-endometrioid endometrial carcinoma—a large-scale, multi-center, and retrospective study

Xiaohang Yang, Jingjing Yin, Yu Fu, Yuanming Shen et al. • Diagnostic Pathology (2023)

Abstract Introduction Myometrial invasion is a prognostic factor for lymph node metastases and decreased survival in non-endometrioid endometrial carcinoma patients. Herein, we explored the mode of myometrial invasion diagnosis in FIGO stag...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13000-023-01294-z

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Vladimir Tesar, Conor Judge, John Kelleher, Zdenka Hrušková et al. • RMD Open (2024)

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS&gt;0) is often missing or inaccurate in re...

DOAJ Open Access (DOAJ) DOI: 10.1136/rmdopen-2023-003962