Academic Articles & Research Papers

The burden and determinants of cognitive impairment among individuals with chronic diseases in Ethiopia: A systematic review and meta-analysis

Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...

Associations between occupational performance and quality of life, well-being, and instrumental activities of daily living in older adults

This study aimed to investigate the associations between occupational performance and quality of life, well-being, and instrumental activities of daily living in older Japanese adults by examining the correlations between the Canadian Occup...

Nordiske sundhedsfremmende perspektiver på ældre menneskers deltagelse og tryghed

Nordic Health Promotion Perspectives on Older Adults Participation and Sense og Security Demographic changes and the growing elderly population in Scandinavia provide an incentive to study Health Ageing in the Nordic Countries. The chose...

Online peer support for Young Onset Dementia is a promising resource, but not a panacea: a commentary from the INTERDEM Young Onset Dementia taskforce

Implementing and Evaluating a National Integrated Digital Registry and Clinical Decision Support System in Early Intervention in Psychosis Services (Early Psychosis Informatics Into Care): Co-Designed Protocol

BackgroundEarly intervention in psychosis (EIP) services are nationally mandated in England to provide multidisciplinary care to people experiencing first-episode psychosis, which disproportionately affects deprived and ethnic minority yout...

Correction: Five-year dementia prediction and decision support system based on real-world data

Prevalence of Constipation in Elderly and Its Association With Dementia and Mild Cognitive Impairment: A Cross-Sectional Study

BackgroundConstipation and dementia have similar epidemiological characteristics. Changes in intestinal flora and characteristics of the brain-gut axis play roles in the pathogeneses of the two diseases, suggesting that there may be a close...

Neuroscience in Medicine

Cytology and Organization of Cell Types: Light and Electron Microscopy Rochelle S. Cohen and Donald W. Pfaff Anatomy of the Spinal Cord and Brain Bruce E. Maley Ion Channels and Electrical Signaling Stanko S. Stojilkovic A. Clinical Correla...

The Effect of Health Literacy on a Brief Intervention to Improve Advance Directive Completion: A Randomized Controlled Study

Objective Completion of an advance directive (AD) document is one component of advanced care planning. We evaluated a brief intervention to enhance AD completion and assess whether the intervention effect varied according to health literacy...

Adoption and Willingness to Pay for Emerging Dementia Therapies: Evidence from a Nationally Representative Survey

Objectives: Decisions about emerging disease-modifying dementia therapies involve both treatment uptake and willingness to pay (WTP), reflecting the monetary valuation of treatment benefits. Existing studies often do not distinguish between...

Epidemiology and risk factors of dementia

ementia refers to a syndrome that is characterised by progressive deterioration of cognitive functions.Neuropsychiatric symptoms, such as apathy, agitation, and depression, are also common.With increasing loss of function, a patient is grad...

Hyperuricemia and dementia – a case-control study

Abstract Background There is evidence that uric acid may have antioxidant and neuroprotective effects and might therefore alter the risk for neurodegenerative diseases such as dementia. So far, the relation between serum uric acid (SUA) lev...

Challenges in community-based recruitment of Alzheimer's disease cases: Experience of the monitoring drug efficacy through multi-omics research initiative in Alzheimer's disease (MEMORI-AD) study

Background The Monitoring drug Efficacy through Multi-Omics Research Initiative in Alzheimer's Disease (MEMORI-AD) study aims to characterize drug response to donepezil and memantine in a Filipino cohort with late-onset Alzheimer's disease ...

Post-diagnostic support for dementia in the UK: mapping access, delivery and gaps in provision.

Methodological framework to identify possible adverse drug reactions using population-based administrative data [v1; ref status: indexed, http://f1000r.es/3ys]

Purpose: We present a framework for detecting possible adverse drug reactions (ADRs) using the Utah Medicaid administrative data. We examined four classes of ADRs associated with treatment of dementia by acetylcholinesterase inhibitors (ACh...

Dementia: a public health priority

Evidence of aberrant anti-epstein-barr virus antibody response, though no viral reactivation, in people with post-stroke fatigue

Abstract Background Fatigue is a common complication of stroke that has a significant impact on quality of life. The biological mechanisms that underly post-stroke fatigue are currently unclear, however, reactivation of latent viruses and t...

Evaluating the accuracy of brief cognitive assessments for the early detection of cognitive impairment in adults across primary and specialty care settings: A systematic review and meta-analysis.

Variation in TMEM106B in chronic traumatic encephalopathy

Abstract The genetic basis of chronic traumatic encephalopathy (CTE) is poorly understood. Variation in transmembrane protein 106B (TMEM106B) has been associated with enhanced neuroinflammation during aging and with TDP-43-related neurodege...

Natural language processing in Alzheimer's disease research: Systematic review of methods, data, and efficacy

Abstract INTRODUCTION Alzheimer's disease (AD) prevalence is increasing, with no current cure. Natural language processing (NLP) offers the potential for non‐invasive diagnostics, social burden assessment, and research advancements in AD. M...