Academic Articles & Research Papers

<i>Escherichia coli</i> Phylogenetic and Antimicrobial Pattern as an Indicator of Anthropogenic Impact on Threatened Freshwater Mussels

Freshwater bivalves are widely used as accumulation indicators and monitoring tools for assessing contaminant effects on different levels of biological integration. This pilot study aimed to explore the phylogenetic diversity of Escherichia...

Single-cell RNA sequencing to detect age-associated genes that identify senescent cells in the liver of aged mice

Abstract Senescent cells are predicted to occur and increase in animal tissues with aging. However, senescent cells in the tissues of aged animals remain to be identified. We refer to the marker genes to identify senescent cells in tissues ...

Dietary Supplementation with the Red Seaweed <i>Porphyra umbilicalis</i> Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice

Some diet profiles are associated with the risk of developing cancer; however, some nutrients show protective effects. Porphyra umbilicalis is widely consumed, having a balanced nutritional profile; however, its potential for cancer chemopr...

Coffee Silverskin Phytocompounds as a Novel Anti-Aging Functional Food: A Pharmacoinformatic Approach Combined with In Vitro Study

Coffee became a beverage that was in demand in the world and consequently produced millions of tons of coffee byproducts namely coffee silverskin (CS). Unutilized CS will be waste and cause environmental pollution such as greenhouse gas emi...

Research in medical informatics

Medical informatics is concerned with the application of computers in the medical and biological sciences and has been considered a field of research in its own right for more than twenty years. In Malaysia, however, there are very few publ...

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden. The globally dominant sequence type 239 (ST239) HA-MRSA clone has persiste...

Genome‐wide association studies of fruit quality traits in jujube germplasm collections using genotyping‐by‐sequencing

Abstract Chinese jujube (Ziziphus jujuba Mill.) is an important fruit crop and harbors many highly diverse traits of potential economic importance. Fruit size, stone size, and fruit cracking have an important influence on the commercial val...

Role of N343 glycosylation on the SARS-CoV-2 S RBD structure and co-receptor binding across variants of concern

Glycosylation of the SARS-CoV-2 spike (S) protein represents a key target for viral evolution because it affects both viral evasion and fitness. Successful variations in the glycan shield are difficult to achieve though, as protein glycosyl...

Impacts of Sugarcane Vinasses on the Structure and Composition of Bacterial Communities in Brazilian Tropical Oxisols

This study explored how different sugarcane vinasses influence the structure and composition of soil bacterial communities in two tropical Oxisols with contrasting textures. In a controlled microcosm experiment with sugarcane seedlings, two...

Statistical Inter-stimulus Interval Window Estimation for Transient Neuromodulation via Paired Mechanical and Brain Stimulation

For achieving motor recovery in individuals with sensorimotor deficits, augmented activation of the appropriate sensorimotor system, and facilitated induction of neural plasticity are essential. An emerging procedure that combines periphera...

Optimizing Post-Curing Protocols for 3D-Printed Dental Models: A Long-Term Evaluation of Mechanical and Physical Properties

This study evaluated the influence of post-polymerization duration and a 14-day aging period on the mechanical and physical properties of 3D-printed standard resin models. Methods: Specimens were printed using Anycubic resin (50 µm layers) ...

Socially intelligent robots: dimensions of human–robot interaction

Social intelligence in robots has a quite recent history in artificial intelligence and robotics. However, it has become increasingly apparent that social and interactive skills are necessary requirements in many application areas and conte...

Quantum computing at the frontiers of biological sciences

Genotypic Variants of Pandemic H1N1 Influenza A Viruses Isolated from Severe Acute Respiratory Infections in Ukraine during the 2015/16 Influenza Season

Human type A influenza viruses A(H1N1)pdm09 have caused seasonal epidemics of influenza since the 2009–2010 pandemic. A(H1N1)pdm09 viruses had a leading role in the severe epidemic season of 2015/16 in the Northern Hemisphere and caused a h...

Evidence of aberrant anti-epstein-barr virus antibody response, though no viral reactivation, in people with post-stroke fatigue

Abstract Background Fatigue is a common complication of stroke that has a significant impact on quality of life. The biological mechanisms that underly post-stroke fatigue are currently unclear, however, reactivation of latent viruses and t...

New topic horizons for drone systems and applications

Summary This journal (Drone Systems and Applications; DSA) conducted a targeted “horizon scan” during 2022 within our team of editors and associate editors. We asked—Which research areas currently under-represented in Drone Systems and Appl...

The transcription factor SoxD controls neuronal guidance in the Drosophila visual system

Abstract Precise control of neurite guidance during development is essential to ensure proper formation of neuronal networks and correct function of the central nervous system (CNS). How neuronal projections find their targets to generate a...

MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites

Abstract Malaria remains one of the deadliest infectious diseases. Transcriptional regulation effects of noncoding variants in this unusual genome of malaria parasites remain elusive. We developed a sequence-based, ab initio deep learning f...

Unraveling the relationship between key aroma components and sensory properties of fragrant peanut oils based on flavoromics and machine learning

Key aroma components of 33 fragrant peanut oils with different aroma types were screened by combined using flavoromics and machine learning. A total of 108 volatile compounds were identified and 100 kinds of them were accurately quantified,...