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Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer

Sophia Daum, Lilith Decristoforo, Mira Mousa, Stefan Salcher et al. • Molecular Cancer (2025)

Abstract The dynamic interactions between tumor endothelial cells (TECs) and the immune microenvironment play a critical role in the progression of non-small cell lung cancer (NSCLC). In general, endothelial cells exhibit diverse immunomodu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-024-02221-6

A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

Henri Schmidt, Arutha Kulasinghe, Richard J.N. Allcock, Lit Yeen Tan et al. • Diagnostics (2018)

Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs. PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway. PIK3CA has been impl...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics8040079

Injectable hyaluronic acid-collagen derived hydrogel based on component biomimetic as vitreous substitute

Shuo Wang, Jinhua Chi, Yanting Wang, Ruibao Ju et al. • Materials & Design (2026)

Vitrectomy is a common clinical treatment for fundus disease. Due to the non-renewable nature of the vitreous, artificial vitreous are usually required to replace natural vitreous to perform functions post operation. Silicone oil and gas, a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.matdes.2026.115780

In vivo and in vitro toxicity of nanogold conjugated snake venom protein toxin GNP-NKCT1

Partha Pratim Saha, Tanmoy Bhowmik, Anjan Kumar Dasgupta, Antony Gomes • Toxicology Reports (2014)

Research on nanoparticles has created interest among the biomedical scientists. Nanoparticle conjugation aims to target drug delivery, increase drug efficacy and imaging for better diagnosis. Toxicity profile of the nanoconjugated molecules...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.toxrep.2014.04.007

Case reports of latent HBV hepatitis in patients after neurosurgical treatment for hypothalamic and pituitary tumors

Kuniyasu Niizuma, Yoshikazu Ogawa, Takayuki Kogure, Teiji Tominaga • BMC Infectious Diseases (2020)

Abstract Background Hepatitis B virus (HBV) infection is a major public health problem worldwide. More than 2 billion people have been exposed to HBV, and about 257 million individuals are chronic carriers of HBV. HBV reactivation has been ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12879-020-04971-2

Sociodemographic Factors and Depression in Patients With Breast Cancer: A Multicenter, Cross-sectional Study in Georgia

Tamar Kakhniashvili, Nino Okribelashvili, Ivane Kiladze • Breast Cancer: Basic and Clinical Research (2025)

Background: Depression commonly occurs in patients with breast cancer (BC), affecting their quality of life. Objectives: The relationships between depression and different sociodemographic characteristics in patients with BC are under-resea...

DOAJ Open Access (DOAJ) DOI: 10.1177/11782234251323775

Reducing Health Anxiety in Patients With Inflammatory Bowel Disease Using Video Testimonials: Pilot Assessment of a Video Intervention

Joel Shor, Yusuke Miyatani, Etsuko Arita, Pohung Chen et al. • JMIR Formative Research (2023)

BackgroundHealth anxiety has many damaging effects on patients with chronic illness. Physicians are often unable to alleviate concerns related to living with a disease that has an impact on daily life, and unregulated websites can overrepre...

DOAJ Open Access (DOAJ) DOI: 10.2196/39945

Adoption and Willingness to Pay for Emerging Dementia Therapies: Evidence from a Nationally Representative Survey

J. Felipe Montano-Campos, Julie Zissimopoulos, Mireille Jacobson, Bryan Tysinger et al. • MDM Policy & Practice (2026)

Objectives: Decisions about emerging disease-modifying dementia therapies involve both treatment uptake and willingness to pay (WTP), reflecting the monetary valuation of treatment benefits. Existing studies often do not distinguish between...

DOAJ Open Access (DOAJ) DOI: 10.1177/23814683261487187

Neutrinos in Physics and Astrophysics

Chung W. Kim, Aihud Pevsner, Frank Seiulli • Physics Today (1995)

This work provides an overview of the subject of neutrino physics that will be of value to both the serious graduate student and the professional physicist. The authors focus on topics vital to the understanding of the intrinsic properties ...

OPENALEX DOI: https://doi.org/10.1063/1.2807980

Adverse skin reactions to antiepileptic drugs - a review

Michalina Gruszczyńska, Adam Jarzemski, Agnieszka Kolossa, Rafał Porzych • Journal of Education, Health and Sport (2023)

Introduction and objective: Treatment with antiepileptic drugs (AEDs) is frequently used all around the world. Just like in the course of all the drugs administration, side effects may appear, including characteristic side effects presentin...

DOAJ Open Access (DOAJ) DOI: 10.12775/JEHS.2023.21.01.002

A Predictive Model Based on the Gut Microbiota Improves the Diagnostic Effect in Patients With Cholangiocarcinoma

Tan Zhang, Tan Zhang, Sina Zhang, Sina Zhang et al. • Frontiers in Cellular and Infection Microbiology (2021)

Cholangiocarcinoma (CCA) is a malignant hepatic tumor with a poor prognosis, which needs early diagnosis urgently. The gut microbiota has been shown to play a crucial role in the progression of liver cancer. Here, we explored a gut microbio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2021.751795

Protocol for a mixed methods process evaluation for a randomised controlled trial to improve shared decision-making about, and uptake of, osteoporosis medicines: the iFraP study [version 3; peer review: 2 approved, 1 approved with reservations]

Terence W O'Neill, Robert Horne, Clare Jinks, Christian D Mallen et al. • NIHR Open Research (2026)

Background High quality shared decision-making (SDM) conversations involve people with or at risk of osteoporosis and clinicians working together to decide, where appropriate, which evidence-based medicines best fit the person’s life, belie...

DOAJ Open Access (DOAJ) DOI: 10.3310/nihropenres.13751.3

Plasma Exchange for ANCA-Associated Vasculitis: An International Survey of Patient PreferencesPlain Language Summary

David Collister, Mark Farrar, Lesha Farrar, Paul Brown et al. • Kidney Medicine (2023)

Rationale & Objective: We sought to elicit patient preferences regarding the use of plasma exchange in antineutrophil cytoplasmic antibody-associated vasculitis (AAV) and its tradeoffs of risk of kidney failure and risk of serious infec...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.xkme.2022.100595

Epidemiology: Beyond the Basics

Robert McCarter • Medicine & Science in Sports & Exercise (2000)

Epidemiology: Beyond the BasicsAuthors: SZKLO, Moyses, MD, DrPH (Johns Hopkins Univ.); NIETO, F. Javier, MD, PhD (Johns Hopkins Univ.) Bibliographic Data: (ISBN: 0–8342-0618–8, Aspen Publishers, Inc., 2000, $55.00) 495 pages, soft cover Aud...

OPENALEX DOI: https://doi.org/10.1097/00005768-200006000-00031

The epidemiology of theileriosis in Africa

R. A. I. Norval, Brian D. Perry, Alan S. Young • CGSPace A Repository of Agricultural Research Outputs (Consultative Group for International Agricultural Research) (1992)

The title of this book does not adequately reflect the comprehensive treatment of a complex and important parasitic disease of domestic cattle. Despite the passing of 100 years, East Coast fever (ECF) remains an economically and environment...

OPENALEX other-oa

Canadian Patterns of Antimicrobial Resistance: Overview of Current Trends Related to Hospital Pathogens

Tony Mazzulli • Canadian Journal of Infectious Diseases and Medical Microbiology (2006)

Selection of appropriate empirical antibiotic therapy is dependent on many factors, not the least of which is an understanding of antimicrobial resistance rates in the patient population that is undergoing treatment. Resistance rates may va...

DOAJ Open Access (DOAJ) DOI: 10.1155/2006/505937

EFFICACY AND SAFETY OF INCLISIRAN BY BASELINE BODY MASS INDEX: A POST HOC POOLED ANALYSIS OF THE ORION-9, ORION-10 AND ORION-11 PHASE III RANDOMIZED CONTROLLED TRIALS

Lawrence A Leiter, David G Kallend, Wolfgang Koenig, Ulf Landmesser et al. • American Journal of Preventive Cardiology (2023)

Therapeutic Area: ASCVD/CVD Risk Factors Background: Excessive bodyweight, often associated with dyslipidemia, may affect the pharmacology of drugs. Inclisiran, a small interfering RNA targeting PCSK9 hepatic mRNA, is an effective LDL-C low...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ajpc.2022.100403

Hyperuricemia and dementia – a case-control study

Bettina Engel, Willy Gomm, Karl Broich, Wolfgang Maier et al. • BMC Neurology (2018)

Abstract Background There is evidence that uric acid may have antioxidant and neuroprotective effects and might therefore alter the risk for neurodegenerative diseases such as dementia. So far, the relation between serum uric acid (SUA) lev...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12883-018-1136-y