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Compression and Tensile Testing of L-PBF Ti-6Al-4V Lattice Structures with Biomimetic Porosities and Strut Geometries for Orthopedic Implants

Dimitri P. Papazoglou, Amy T. Neidhard-Doll, Margaret F. Pinnell, Dathan S. Erdahl et al. • Metals (2024)

In an effort to contribute to the ongoing development of ASTM standards for additively manufactured metal lattice specimens, particularly within the field of medicine, the compressive and tensile mechanical properties of biomimetic lattice ...

DOAJ Open Access (DOAJ) DOI: 10.3390/met14020232

Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study

Chung-woo Lee, Joo Kyung Lee, Yeon Joo Choi, Hyunjin Kim et al. • Scientific Reports (2022)

Abstract Revascularization procedures, including percutaneous coronary intervention (PCI), for coronary artery disease (CAD) are increasingly performed in Korea. However, studies on blood pressure control targets in these patients remain in...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-06627-4

Ethical and social implications of approaching death prediction in humans - when the biology of ageing meets existential issues

Marie Gaille, Marco Araneda, Clément Dubost, Clémence Guillermain et al. • BMC Medical Ethics (2020)

Abstract Background The discovery of biomarkers of ageing has led to the development of predictors of impending natural death and has paved the way for personalised estimation of the risk of death in the general population. This study inten...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12910-020-00502-5

Smoking behavior change and the risk of pneumonia hospitalization among smokers with diabetes mellitus

Dong-Woo Han, Wonyoung Jung, Kyu Na Lee, Kyungdo Han et al. • Scientific Reports (2023)

Abstract Smoking patients with diabetes mellitus (DM) are at greater risk of developing pneumonia. How smoking behavior changes affect the risk of pneumonia hospitalization, however, remains unclear. Therefore, we investigated the associati...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-40658-9

Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types

Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li et al. • Molecular Cancer (2021)

Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-021-01362-2

Long-Term Prognosis and Systemic Impact of Acromegaly: Analyses Utilizing Korean National Health Insurance Data

Sangmo Hong, Kyungdo Han, Cheol-Young Park • Endocrinology and Metabolism (2025)

Acromegaly is a rare endocrine disorder caused by excessive growth hormone secretion. Its low prevalence poses challenges in studying its long-term prognosis and systemic effects. To address this research gap, we conducted five studies usin...

DOAJ Open Access (DOAJ) DOI: 10.3803/EnM.2024.2285

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

Yan Dora Zhang, Amber N. Hurson, Haoyu Zhang, Parichoy Pal Choudhury et al. • Nature Communications (2020)

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-020-16483-3

Ranking of treatments in network meta-analysis: incorporating minimally important differences

Tristan Curteis, Augustine Wigle, Christopher J. Michaels, Adriani Nikolakopoulou • BMC Medical Research Methodology (2025)

Abstract Background In network meta-analysis (NMA), the magnitude of difference between treatment effects is typically ignored in the calculation of ranking metrics, such as probability best and surface under the cumulative ranking curve (S...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12874-025-02499-0

The risk of colorectal cancer according to obesity status at four-year intervals: a nationwide population-based cohort study

Ji Yeon Seo, Eun Hyo Jin, Goh Eun Chung, Young Sun Kim et al. • Scientific Reports (2023)

Abstract Obesity is a risk factor for colorectal cancer. However, the effect of body weight change on colorectal cancer is uncertain. This study aimed to investigate the relationship between difference in body mass index and the risk of col...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-36111-6

Metabolomic sweet spot clock predicts mortality and age-related diseases in the Canadian Longitudinal Study on Aging

Olga Vishnyakova, Joosung Min, Stephen Leach, Xiaowei Song et al. • Communications Medicine (2026)

Abstract Background Chronological age does not capture individual health or resilience. Advances in metabolomics have enabled development of molecular aging biomarkers that capture deviations between biological and chronological age, highli...

DOAJ Open Access (DOAJ) DOI: 10.1038/s43856-026-01375-2

Increased prevalence of loneliness and associated risk factors during the COVID-19 pandemic: findings from the Canadian Longitudinal Study on Aging (CLSA)

Susan A. Kirkland, Lauren E. Griffith, Urun Erbas Oz, Mary Thompson et al. • BMC Public Health (2023)

Abstract Background Older adults have been disproportionately impacted by COVID-19 and related preventative measures undertaken during the pandemic. Given clear evidence of the relationship between loneliness and health outcomes, it is impe...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12889-023-15807-4

The beneficial effects of menopausal hormone therapy on renal survival in postmenopausal Korean women from a nationwide health survey

Shin Young Ahn, Yoon Jin Choi, Jieun Kim, Gang Jee Ko et al. • Scientific Reports (2021)

Abstract Several studies have demonstrated the nephroprotective effects of estrogen on renal damage. In light of the inconsistent results of previous findings, this study aims to evaluate the in-depth role of menopausal hormone therapy (MHT...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-93847-9

Factors Affecting High Body Weight Variability

Kyungdo Han, Mee Kyoung Kim • Journal of Obesity & Metabolic Syndrome (2023)

Background : High body weight variability (BWV) is associated with many metabolic and cardiovascular diseases in adults. The study was designed to explore the baseline characteristics associated with high BWV. Methods : Using a nationally r...

DOAJ Open Access (DOAJ) DOI: 10.7570/jomes22063

Clustering of Unhealthy Lifestyle and the Risk of Adverse Events in Patients With Atrial Fibrillation

So-Ryoung Lee, Eue-Keun Choi, Eue-Keun Choi, Sang-Hyeon Park et al. • Frontiers in Cardiovascular Medicine (2022)

BackgroundLittle is known regarding the risk of clinical outcomes depending on the clustering of lifestyle behaviors after atrial fibrillation (AF) diagnosis. This study evaluated the association between a cluster of healthy lifestyle behav...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2022.885016

Fatty Liver & Diabetes Statistics in Korea: Nationwide Data 2009 to 2017

Eugene Han, Kyung-Do Han, Yong-ho Lee, Kyung-Soo Kim et al. • Diabetes & Metabolism Journal (2023)

Background This study investigated the changes of fatty liver disease prevalence in general Korean population. Methods This study analyzed data from the Korean National Health Insurance Service from 2009 to 2017 that included individuals ag...

DOAJ Open Access (DOAJ) DOI: 10.4093/dmj.2022.0444

Cumulative Exposure to High γ-Glutamyl Transferase Level and Risk of Diabetes: A Nationwide Population-Based Study

Ji-Yeon Park, Kyungdo Han, Hun-Sung Kim, Jae-Hyoung Cho et al. • Endocrinology and Metabolism (2022)

Background Elevated γ-glutamyl transferase (γ-GTP) level is associated with metabolic syndrome, impaired glucose tolerance, and insulin resistance, which are risk factors for type 2 diabetes. We aimed to investigate the association of cumul...

DOAJ Open Access (DOAJ) DOI: 10.3803/EnM.2022.1416

Cost of inaction: a framework to estimate the economic cost of missing a patient with tuberculosis in the Indian context

Salmaan Keshavjee, Meredith B Brooks, Tom Nicholson, Viswanath Pingali • BMJ Open (2023)

Objectives To estimate the economic impact of failure to find and treat tuberculosis disease and prevent tuberculosis infection from progressing to active disease.Design Estimating the economic cost of not finding and treating a patient suf...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2022-070717

Which scoring systems are useful for predicting the prognosis of lower gastrointestinal bleeding? Old and new

Ku Bean Jeong, Hee Seok Moon, Kyung Ryun In, Sun Hyung Kang et al. • BMC Gastroenterology (2025)

Abstract Background The incidence of lower gastrointestinal bleeding is on the rise, prompting the creation of various scoring systems to forecast patient’s outcomes. But there is no single unified scoring system and these scoring systems c...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12876-025-03638-z

Estimated pulse wave velocity and progression to advanced cardiovascular–kidney–metabolic syndrome: a population-based longitudinal study with supportive external cross-sectional evidence

Wenjiao Zhang, Wenjiao Zhang, Wenbo Yang, Wenbo Yang et al. • Frontiers in Cardiovascular Medicine (2026)

BackgroundCardiovascular–kidney–metabolic (CKM) syndrome captures the interconnected burden of metabolic risk factors, chronic kidney disease, and cardiovascular disease. Evidence remains limited regarding simple and clinically accessible m...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcvm.2026.1875961