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Academic Articles & Research Papers
Showing 20 of 2,024 academic articles
Johan Bertilsson, Johan Bertilsson, Diederick C. Niehorster, Diederick C. Niehorster et al. • Frontiers in Psychology
(2019)
Police work may include performing repeated tasks under the influence of psychological stress, which can affect perceptual, cognitive and motor performance. However, it is largely unknown how repeatedly performing stressful tasks physically...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fpsyg.2019.01562
Yashaswini Reddy, Gargi Joshi, Swechha Mahapatra, Ipshita Das et al. • Journal of Genetic Engineering and Biotechnology
(2026)
RECQ helicases involve a family of DNA unwinding enzymes, namely, RECQ1, Bloom syndrome protein, Werner syndrome protein, RECQL4, and RECQ5. These proteins interact with various proteins to form complexes and carry out a range of physiologi...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.jgeb.2026.100824
Juan Carlos Lopez-Baez, Daniel J Simpson, Laura LLeras Forero, Zhiqiang Zeng et al. • eLife
(2018)
Regenerative therapy for degenerative spine disorders requires the identification of cells that can slow down and possibly reverse degenerative processes. Here, we identify an unanticipated wound-specific notochord sheath cell subpopulation...
DOAJ
Open Access (DOAJ)
DOI: 10.7554/eLife.30657
Mahta Karimpoor, Nathan W. Churchill, Fred Tam, Corinne E. Fischer et al. • Frontiers in Human Neuroscience
(2018)
Handwriting is a complex human activity that engages a blend of cognitive and visual motor skills. Current understanding of the neural correlates of handwriting has largely come from lesion studies of patients with impaired handwriting. Tas...
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Open Access (DOAJ)
DOI: 10.3389/fnhum.2018.00030
Noela Rodriguez-Losada, Noela Rodriguez-Losada, Rune Wendelbob, M. Carmen Ocaña et al. • Frontiers in Neuroscience
(2020)
Emerging scaffold structures made of carbon nanomaterials, such as graphene oxide (GO) have shown efficient bioconjugation with common biomolecules. Previous studies described that GO promotes the differentiation of neural stem cells and ma...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnins.2020.570409
Yuxiong Lu, Junichi Maruyama, Keiko Kuwata, Hiroyuki Fukuda et al. • Biochemistry and Biophysics Reports
(2018)
Doublecortin-like kinase 1 (DCLK1) is a serine/threonine-kinase with two doublecortin (DCX) domains. DCLK1 is associated with microtubules via DCX domains and regulates microtubule polymerization. DCLK1 is known to be expressed in cancer st...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.bbrep.2018.10.014
Nobuhiko Kajinami, Mitsuhiro Matsumoto • Biophysics and Physicobiology
(2019)
Human knee joints move smoothly under high load conditions due to articular cartilage and synovial fluid. Much attention is paid to the role of proteoglycans. It is suggested that a part of proteoglycan forms aggregate on the cartilage surf...
DOAJ
Open Access (DOAJ)
DOI: 10.2142/biophysico.16.0_466
Adam H. Tencer, Jiuyang Liu, Jing Zhu, Nathaniel T. Burkholder et al. • Scientific Reports
(2022)
Abstract The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protein. Here, we show that the ZZ domain of HERC2 (HERC2ZZ) recognizes a mimetic of the Nt-R cargo ...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41598-022-10119-w
Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova et al. • Communications Biology
(2022)
Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms....
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s42003-022-03753-7
Khushboo Singh, Roon Banerjee, Chandrakanta Potdar, Anisha Shaw et al. • Cells
(2026)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are among the most common genetic causes of Parkinson’s disease (PD), yet substantial heterogeneity exists among pathogenic variants. How mutations in distinct functional domains of LRRK2 di...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cells15040342
Stefania Martucciello, Marchesa Bilio, Sara Cioffi, Ilaria Aurigemma et al. • Journal of Cardiovascular Development and Disease
(2026)
Gene inactivation in model organisms has identified numerous genes and signaling pathways involved in mammalian cardiac outflow tract (OFT) development. Human genetics data have implicated the VEGFR3 gene in OFT development, but when and wh...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/jcdd13080399
Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares et al. • Molecules
(2021)
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules26226923
Natsuko Kitajima, Takahisa Nakajo, Takeshi Katayoshi, Kentaro Tsuji-Naito • Biochemistry and Biophysics Reports
(2023)
Sebocytes express Toll-like receptors (TLRs) and nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs), which participate in the innate immune response of the skin. Although the roles of TLRs and NLR family pyrin domain-cont...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.bbrep.2023.101561
Irandi Putra Pratomo, Dimas R. Noor, Kusmardi Kusmardi, Andriansjah Rukmana et al. • International Journal of Inflammation
(2021)
Xanthine oxidase (XO) is an enzyme that catalyzes the production of uric acid and superoxide radicals from purine bases: hypoxanthine and xanthine and is also expressed in respiratory epithelial cells. Uric acid, which is also considered a ...
DOAJ
Open Access (DOAJ)
DOI: 10.1155/2021/1653392
Xhulio Dhori, Silvia Gioiosa, Stefania Gonfloni • Scientific Data
(2024)
Abstract Granulosa cells (GCs) play crucial roles in oocyte maturation. Through gap junctions and extracellular vesicles, they mediate the exchange of molecules such as microRNAs and messenger RNAs. Different ovarian cell types exhibit uniq...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41597-024-03715-0
O. A. Gromova, I. Yu. Torshin, A. G. Moiseenok • Фармакоэкономика
(2025)
Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect ...
DOAJ
Open Access (DOAJ)
DOI: 10.17749/2070-4909/farmakoekonomika.2024.285
Shih-Ho Wang, Chin-Hu Wu, Chin-Chuan Tsai, Tai-Yu Chen et al. • Current Issues in Molecular Biology
(2022)
Taraxacum officinale (dandelion) is often used in traditional Chinese medicine for the treatment of cancer; however, the downstream regulatory genes and signaling pathways mediating its effects on breast cancer remain unclear. The present s...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cimb44050142
Brianna Dufek, Daniel T Meehan, Duane Delimont, Kevin Wilhelm et al. • PLoS ONE
(2020)
Previous work demonstrates that the hearing loss in Alport mice is caused by defects in the stria vascularis. As the animals age, progressive thickening of strial capillary basement membranes (SCBMs) occurs associated with elevated levels o...
DOAJ
Open Access (DOAJ)
DOI: 10.1371/journal.pone.0237907
Dakshinamurthy Sivakumar, Natarajan Hari, Thirunavukkarasu Sivaraman • Bangladesh Journal of Pharmacology
(2014)
We have herein computationally examined binding affinities and specificity of 2-hydroxy-3,5-dinitrobenzamide (HDNB), a small chemical molecular BH3-mimetic identified by means of peptidodynmimetic method, on the BH3-binding grooves of six...
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Open Access (DOAJ)
Justin Rashtian, Diana E. Chavkin, Zaher Merhi • Reproductive Biology and Endocrinology
(2019)
Abstract A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that could incur adverse repr...
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Open Access (DOAJ)
DOI: 10.1186/s12958-018-0448-5