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Musculoskeletal pain is not clearly associated with the risk of anterior cruciate ligament reconstruction in adolescents

John-Anker Zwart, Kjersti Storheim, Anne Marie Fenstad, Maren Hjelle Guddal et al. • BMJ Open Sport & Exercise Medicine (2023)

Objectives The purpose of this study was to investigate whether self-reported musculoskeletal pain (MSP) was associated with a future anterior cruciate ligament reconstruction (ACLR).Methods In this population-based prospective cohort study...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjsem-2022-001453

Health technology assessment development in China

Yingyao Chen, David Banta, Zhiliu Tang • International Journal of Technology Assessment in Health Care (2009)

OBJECTIVES: This study is to review health technology assessment (HTA) development in China during the past two decades, and to facilitate further development of HTA and its integration into policy making. METHODS: The study depends very mu...

OPENALEX Open Access DOI: https://doi.org/10.1017/s0266462309090643

Memory and Synaptic Devices Based on Emerging 2D Ferroelectricity

Yanggeun Joo, Eunji Hwang, Heemyoung Hong, Suyeon Cho et al. • Advanced Electronic Materials (2023)

Abstract Memory devices are an essential part of modern electronics. Efforts to move beyond the traditional “read” and “write” of digital information in volatile and non‐volatile memory devices are leading to the rapid growth of neuromorphi...

DOAJ Open Access (DOAJ) DOI: 10.1002/aelm.202300211

Pathway analysis of the impact of family function and self-efficacy on depression and anxiety in patients undergoing in vitro fertilization-embryo transfer

Fangliang Zou, Yi Fang, Yanshan Lin, Zikai Feng et al. • BMC Psychology (2024)

Abstract Background Patients undergoing assisted reproductive technology (ART) experience significant psychological distress due to infertility, with depression and anxiety being the most common manifestations. This study investigates the i...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40359-024-02246-y

Research on older people's health information search behavior based on risk perception in social networks—A case study in China during COVID-19

Chi Zhang, Chi Zhang, Wei Fang Liao, Yi Ming Ma et al. • Frontiers in Public Health (2022)

ObjectiveCOVID-19 has caused great loss of human life and livelihoods. The dissemination of health information in online social networks increased during the pandemic's quarantine. Older people are the most vulnerable group in sudden public...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2022.946742

Analysing criteria for price and reimbursement of orphan drugs in Spain

Xavier Badia, Alicia Gil, José Luis Poveda-Andrés, John Shepherd et al. • Farmacia Hospitalaria (2019)

Objective: There are differences between countries regarding data requirements for orphan drug evaluation and it is also unknown which criteria might determine the price and reimbursement decision. This study aimed to identify the key c...

DOAJ Open Access (DOAJ) DOI: 10.7399/fh.11147

International practices in health technology assessment and public financing of digital health technologies: recommendations for Hungary

Fruzsina Mezei, Krisztián Horváth, M. Pálfi, Kornélia Lovas et al. • Frontiers in Public Health (2023)

Background: Evaluating and integrating digital health technologies is a critical component of a national healthcare ecosystem in the 2020s and is expected to even increase in significance. Design: The paper gives an overview of internationa...

OPENALEX cc-by DOI: https://doi.org/10.3389/fpubh.2023.1197949 PMC: 10501404

Methods for Population-Adjusted Indirect Comparisons in Health Technology Appraisal

David Phillippo, Anthony E. Ades, Sofia Dias, Stephen Palmer et al. • Medical Decision Making (2017)

Standard methods for indirect comparisons and network meta-analysis are based on aggregate data, with the key assumption that there is no difference between the trials in the distribution of effect-modifying variables. Methods which relax t...

OPENALEX cc-by DOI: https://doi.org/10.1177/0272989x17725740 PMC: 5774635

Barriers and facilitators of retention in care after cervical cancer screening: patients’ and healthcare providers’ perspectives

Judith Owokuhaisa, Eleanor Turyakira, Frank Ssedyabane, Deusdedit Tusubira et al. • BMC Women's Health (2024)

Abstract Background Cervical cancer continues to threaten women’s health, especially in low-resource settings. Regular follow-up after screening and treatment is an effective strategy for monitoring treatment outcomes. Consequently, underst...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12905-024-03343-1

A hybrid plasmid formed by recombination of a virulence plasmid and a resistance plasmid in Klebsiella pneumoniae

Miaomiao Xie, Ning Dong, Kaichao Chen, Xuemei Yang et al. • Journal of Global Antimicrobial Resistance (2020)

Objective: The emergence of multidrug-resistant (MDR) and hypervirulent Klebsiella pneumoniae (hvKP) facilitates simultaneous dissemination of virulence and resistance in a single event, which poses serious threat to public health. Methods:...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jgar.2020.10.018

Design and Optimization of Trastuzumab-Functionalized Nanolipid Carriers for Targeted Capecitabine Delivery: Anti-Cancer Effectiveness Evaluation in MCF-7 and SKBR3 Cells

Das S, Satapathy BS, Pattnaik G, Pattanaik S et al. • International Journal of Nanomedicine (2025)

Shubhashree Das,1 Bhabani Sankar Satapathy,2 Gurudutta Pattnaik,1 Sovan Pattanaik,3 Yahya Alhamhoom,4 Mohamed Rahamathulla,4 Mohammed Muqtader Ahmed,5 Ismail Pasha6 1Department of Pharmaceutics, School of Pharmacy and Life Sciences, Centuri...

DOAJ Open Access (DOAJ)

Semaphorin 3A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8+ T cells

Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin et al. • Nature Communications (2024)

Abstract Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-024-47424-z

Instruments measuring the quality of life among people living with type 2 diabetes mellitus in India: a systematic review protocol

Chetna Demla, Anns Thomas, Jomol Jose, Angela L Joshy et al. • BMJ Open (2021)

Introduction Type 2 diabetes mellitus affects an individual’s quality of life (QoL); and there are multiple instruments that can be used to measure QoL. The purpose of this systematic review is to identify the existing instruments that have...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2020-043831

Health technology assessment to optimize health technology utilization: Using implementation initiatives and monitoring processes

Katrine Bjørnebek Frønsdal, Karen M. Facey, Marianne Klemp, Inger Natvig Norderhaug et al. • International Journal of Technology Assessment in Health Care (2010)

BACKGROUND: The way in which a health technology is used in any particular health system depends on the decisions and actions of a variety of stakeholders, the local culture, and context. In 2009, the HTAi Policy Forum considered how health...

OPENALEX Open Access DOI: https://doi.org/10.1017/s0266462310000309

Tecnologia educacional como estratégia de empoderamento de pessoas com enfermidades crônicas [Educational technology as a strategy for the empowerment of people with chronic illnesses]

Lina Márcia Miguéis Berardinelli, Nathália Aparecida Costa Guedes, Juliana Pereira Ramos, Michelle Garcia Nascimento e Silva • Revista Enfermagem UERJ (2015)

Os objetivos deste estudo foram: desenvolver o trabalho em grupo a fim de conhecer o cotidiano e o processo saúde/adoecimento/cuidado das pessoas com enfermidades crônicas; e analisar se o trabalho de grupo potencializou o empoderamento e q...

DOAJ Open Access (DOAJ)

Conserved lipid-facing basic residues promote the insertion of the porin OmpC into the E. coli outer membrane

Janine H. Peterson, Lixinhao Yang, James C. Gumbart, Harris D. Bernstein • mBio (2025)

ABSTRACT Almost all integral membrane proteins that reside in the outer membrane (OM) of gram-negative bacteria contain a closed amphipathic β sheet (“β barrel”) that serves as a membrane anchor. The membrane integration of β barrel structu...

DOAJ Open Access (DOAJ) DOI: 10.1128/mbio.03319-24

Green synthesis and characterization of silver nanoparticles through the Piper cubeba ethanolic extract and their enzyme inhibitory activities

Khalil Ahmad, Hafiz Muhammad Asif, Taimoor Afzal, Mohsin Abbas Khan et al. • Frontiers in Chemistry (2023)

Introduction: The area of “Green Synthesis of Nano-medicine,” as compared to its synthetic counterparts, is a relatively safer research technology for various biomedical applications, including identification, therapeutic application, and p...

DOAJ Open Access (DOAJ) DOI: 10.3389/fchem.2023.1065986

HEALTH TECHNOLOGY ASSESSMENT EVIDENCE ON E-HEALTH/M-HEALTH TECHNOLOGIES: EVALUATING THE TRANSPARENCY AND THOROUGHNESS

Vladimir Vuković, Carlo Favaretti, Walter Ricciardi, Chiara de Waure • International Journal of Technology Assessment in Health Care (2018)

OBJECTIVES: Evaluation is crucial for integration of e-Health/m-Health into healthcare systems and health technology assessment (HTA) could offer sound methodological basis for these evaluations. Aim of this study was to look for HTA report...

OPENALEX DOI: https://doi.org/10.1017/s0266462317004512

Cost-Effectiveness Analysis of Pan-Genotypic Sofosbuvir-Based Regimens for Treatment of Chronic Hepatitis C Genotype 1 Infection in China

Hui Jun Zhou, Jing Cao, Hui Shi, Nasheen Naidoo et al. • Frontiers in Public Health (2021)

Background: Hepatitis C virus (HCV) genotype 1 is the most prevalent HCV infection in China. Sofosbuvir-based direct antiviral agent (DAA) regimens are the current mainstays of treatment. Sofosbuvir/velpatasvir (SOF/VEL) and sofosbuvir/ledi...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2021.779215

Semi-rational design and modification of phosphoketolase to improve the yield of tyrosol in Saccharomyces cerevisiae

Na Song, Huili Xia, Yaoru Xie, Shuaikang Guo et al. • Synthetic and Systems Biotechnology (2025)

Tyrosol is an important component of pharmaceuticals, nutraceuticals, and cosmetics, and their biosynthetic pathways are currently a hot research topic. d-Erythrose 4-phosphate is a key precursor for the biosynthesis of tyrosol in Saccharom...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.synbio.2024.11.007