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The structural characteristics and influential factors of psychological stress of urban residents in Jiangxi province during the COVID-19 pandemic: cross sectional study

Zewen Huang, Lejun Zhang, Junyu Wang, Lu Xu et al. • Heliyon (2021)

Aims: To explore the structural characteristics and influential factors of psychological stress of urban residents in Jiangxi province during the COVID-19 pandemic through a survey of psychological stress, personality traits, family functio...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2021.e07829

Cognitive biases in nursing students' clinical decision-making: insights from high-fidelity simulation using think-aloud and observational methods

Naim Abdulmohdi • Frontiers in Medicine (2026)

BackgroundCognitive biases are systematic errors in human reasoning that can compromise clinical decision-making (CDM) in healthcare. While extensively studied in medicine, nursing research on cognitive biases in CDM remains limited.AimThis...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2026.1984162

Contrast Sensitivity Is Associated With Chorioretinal Thickness and Vascular Density of Eyes in Simple Early-Stage High Myopia

Xinting Liu, Yanli Wang, Xiaoxiao Ying, Fen Zhang et al. • Frontiers in Medicine (2022)

ObjectiveTo evaluate the contrast sensitivity function (CSF), chorioretinal thickness and vascular density as well as their relationships in subjects with simple early-stage high myopia.MethodsEighty-one young subjects were enrolled in this...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.847817

Identification of Lichen Based on Substrate in Bale Village, Tanantovea District, Donggala Regency

Adrian Adrian, Lilies Lilies, Lestari MP Alibasyah, Bustamin Bustamin et al. • Biology, Medicine & Natural Product Chemistry (2026)

Lichens are associations between fungi and photosynthetic symbionts, such as algae or cyanobacteria, that form stable and specialized thallus structures. The fungi that predominantly compose the lichen body belong to the Ascomycetes, while ...

DOAJ Open Access (DOAJ) DOI: 10.14421/biomedich.2026.151.605-611

Biosynthesis of rare 20(R)-protopanaxadiol/protopanaxatriol type ginsenosides through Escherichia coli engineered with uridine diphosphate glycosyltransferase genes

Lu Yu, Yuan Chen, Jie Shi, Rufeng Wang et al. • Journal of Ginseng Research (2019)

Background: Ginsenosides are known as the principal pharmacological active constituents in Panax medicinal plants such as Asian ginseng, American ginseng, and Notoginseng. Some ginsenosides, especially the 20(R) isomers, are found in trace ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jgr.2017.09.005

Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding

Yong Han, Guobin Xia, Dollada Srisai, Fantao Meng et al. • Nature Communications (2021)

Neuronal signaling has an important role in the regulation of energy expenditure and body weight, however, the underlying mechanisms are incompletely understood. Here, the authors report a AgRP-MC4R-serotonin expressing neuronal circuit tha...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-23846-x

Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair

Juan Carlos Lopez-Baez, Daniel J Simpson, Laura LLeras Forero, Zhiqiang Zeng et al. • eLife (2018)

Regenerative therapy for degenerative spine disorders requires the identification of cells that can slow down and possibly reverse degenerative processes. Here, we identify an unanticipated wound-specific notochord sheath cell subpopulation...

DOAJ Open Access (DOAJ) DOI: 10.7554/eLife.30657

Graphene Oxide and Reduced Derivatives, as Powder or Film Scaffolds, Differentially Promote Dopaminergic Neuron Differentiation and Survival

Noela Rodriguez-Losada, Noela Rodriguez-Losada, Rune Wendelbob, M. Carmen Ocaña et al. • Frontiers in Neuroscience (2020)

Emerging scaffold structures made of carbon nanomaterials, such as graphene oxide (GO) have shown efficient bioconjugation with common biomolecules. Previous studies described that GO promotes the differentiation of neural stem cells and ma...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2020.570409

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang et al. • Nature Communications (2021)

The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery....

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-021-24131-7

Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability

Yuxiong Lu, Junichi Maruyama, Keiko Kuwata, Hiroyuki Fukuda et al. • Biochemistry and Biophysics Reports (2018)

Doublecortin-like kinase 1 (DCLK1) is a serine/threonine-kinase with two doublecortin (DCX) domains. DCLK1 is associated with microtubules via DCX domains and regulates microtubule polymerization. DCLK1 is known to be expressed in cancer st...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.bbrep.2018.10.014

Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity

Dipsikha Biswas, Logan Slade, Luke Duffley, Neil Mueller et al. • Cell Death Discovery (2021)

Proposed mechanism. A Doxorubicin (DOX) targets the BCAA catabolic pathway in TNBCs, by downregulating BCKDK and augmenting clearance of intracellular BCKAs. B Genetic or pharmacological (high BT2 concentration) inhibition of BCKDK results ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41420-021-00602-0

Involvement of two uptake mechanisms of gold and iron oxide nanoparticles in a co-exposure scenario using mouse macrophages

Dimitri Vanhecke, Dagmar A. Kuhn, Dorleta Jimenez de Aberasturi, Sandor Balog et al. • Beilstein Journal of Nanotechnology (2017)

Little is known about the simultaneous uptake of different engineered nanoparticle types, as it can be expected in our daily life. In order to test such co-exposure effects, murine macrophages (J774A.1 cell line) were incubated with gold (A...

DOAJ Open Access (DOAJ) DOI: 10.3762/bjnano.8.239

Mechanistic insights into TAM-mediated OMP assembly in Gram-negative bacteria

Qinghua Luo, Xintan Dong, Zhaxi Zerang, Yujiao Chen et al. • Cell Reports (2026)

Summary: The β-barrel assembly machinery (BAM) is essential for outer membrane protein (OMP) biogenesis in Gram-negative bacteria and represents a validated target for antibiotic development. Its evolutionary relative, the translocation and...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.celrep.2026.117733

Modeling SARS-CoV-2 and influenza infections and antiviral treatments in human lung epithelial tissue equivalents

Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova et al. • Communications Biology (2022)

Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms....

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-022-03753-7

The Vibrio vulnificus stressosome is an oxygen-sensor involved in regulating iron metabolism

Veronika Heinz, Wenke Jäckel, Susann Kaltwasser, Laura Cutugno et al. • Communications Biology (2022)

A cryo-electron microscopy reconstruction of a stressosome complex from a Gram-negative bacterium, Vibrio vulnificus, reveals variations in subunit composition and symmetry, which could serve to adjust the activation threshold in the respon...

DOAJ Open Access (DOAJ) DOI: 10.1038/s42003-022-03548-w

Roles of Rap1 signaling in tumor cell migration and invasion

Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine (2017)

Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...

DOAJ Open Access (DOAJ) DOI: 10.20892/j.issn.2095-3941.2016.0086

Dielectric Properties of Phosphatidylcholine Membranes and the Effect of Sugars

Victoria Vitkova, Vesela Yordanova, Galya Staneva, Ognyan Petkov et al. • Membranes (2021)

Simple carbohydrates are associated with the enhanced risk of cardiovascular disease and adverse changes in lipoproteins in the organism. Conversely, sugars are known to exert a stabilizing effect on biological membranes, and this effect is...

DOAJ Open Access (DOAJ) DOI: 10.3390/membranes11110847

Effects of the Brazilian Native Fruit Jaboticaba (<i>Plinia cauliflora</i>) Peel on Inflammatory and Oxidative Stress Pathways: Insights from a Pilot Study in Hemodialysis Patients and Renal Cell Models

Ligia Soares Lima, Jessyca Sousa de Brito, Marcelo Ribeiro-Alves, Karen Salve Coutinho-Wolino et al. • Foods (2025)

Jaboticaba (Plinia cauliflora), a Brazilian native fruit rich in bioactive compounds, exhibits potent anti-inflammatory and antioxidant properties. This pilot study evaluated the effects of jaboticaba peel supplementation on inflammatory an...

DOAJ Open Access (DOAJ) DOI: 10.3390/foods14234030