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Academic Articles & Research Papers
Showing 20 of 1,732 academic articles
Lior Rennert, Corey A. Kalbaugh, Christopher McMahan, Lu Shi et al. • BMC Public Health
(2021)
Abstract Background Several American universities have experienced COVID-19 outbreaks, risking the health of their students, employees, and local communities. Such large outbreaks have drained university resources and forced several institu...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12889-021-11525-x
Xiao Lin, Jun-Jie Yang, Bei Huang, Peng-Xin Wang et al. • Experimental Gerontology
(2026)
Background: BMI cannot distinguish fat distribution and may mask the true effects of different fat depots on bone mineral density (BMD). To investigate sex- and age-specific associations between fat distribution and BMD and its mediating ro...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2026.113301
Chen Chen, Qi Zhou, Ruiyue Yang, Zhu Wu et al. • Ecotoxicology and Environmental Safety
(2021)
Background: Excessive copper (Cu) has risky effect on insulin resistance (IR), oxidative stress and inflammation. Instead, some studies reported serum Cu to be protective for non-alcoholic fatty liver disease (NAFLD). The aim of this study ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ecoenv.2021.112295
Hsiao-Mei Chen, Ching-Min Chen • International Journal of Gerontology
(2017)
Background: There have been many studies reviewing quality of life (QoL) of older population and found an inverse association between QoL and chronic diseases. However, previous studies have focused only on that of people with specific dise...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ijge.2016.07.002
Claudia Contreras, Diana Paola Córdoba‐Rodríguez, Robinson Cuadros, José Ricardo Jauregui et al. • JCSM Communications
(2026)
ABSTRACT Background Secondary sarcopenia driven by chronic disease, acute illness, immobilization, malnutrition or treatment‐related factors contributes to functional decline, falls, disability, readmission and mortality. In Colombia, uneve...
DOAJ
Open Access (DOAJ)
DOI: 10.1002/rco2.70051
Maria Luiza Lima-Silva, Karen Cecília Lima Torres, Juliana Vaz de Melo Mambrini, Nathalia Coimbra Brot et al. • Experimental Gerontology
(2024)
Immunosenescence is a phenomenon caused by changes in the immune system, and part of these changes involves an increase in circulating immunological biomarkers, a process known as “Inflammaging.” Inflammaging can be associated with many dis...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2024.112433
Lin-lin Yao, Xiao-ting Ma, Fang-bo Li, Lin-yi Zheng et al. • Experimental Gerontology
(2026)
Background: Alzheimer's disease (AD) is a neurodegenerative disorder primarily characterized by cognitive dysfunction. The discovery and identification of non-cognitive symptoms in the preclinical stage hold promise for early diagnosis and ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2026.113057
Meng Zhang, Ping He, Zhigang Bian • Frontiers in Molecular Neuroscience
(2021)
Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS), are progressive and ultimately fatal. NDD onset is influenced by several fa...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnmol.2021.685143
Lauren M. Herr, Swagata Mukhopadhyay, Olivia M. Anderson, Tucker H. Couch et al. • Communications Biology
(2026)
Abstract DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary structures that present a substant...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s42003-026-09966-4
Lan Chen, Jing-Xin Zhang, Dong-Ge Liu, Hong-Gang Liu • Diagnostics
(2023)
This paper illustrates a rare syndrome of multiple endocrine neoplasia type 2A (MEN2A) in a family of three generations. In our case, the father, son and one daughter developed phaeochromocytoma (PHEO) and medullary thyroid carcinoma (MTC) ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/diagnostics13050955
Junqi Yang, Yumin Ma, Jiang Liu, Qingtian Zhu et al. • Experimental Gerontology
(2024)
The aging of pancreatic beta cells is closely associated with various diseases, such as impaired glucose tolerance, yet the underlying regulatory mechanisms remain unclear. In this study, we screened young and aged mouse pancreatic beta cel...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2024.112633
Yi-Shan Jiang, Hong Shi, Yu-Ting Kang, Ji Shen et al. • BMC Geriatrics
(2023)
Abstract Background The World Health Organization (WHO) has proposed healthy aging framework, supposing that intrinsic capacity (IC), environment and their interaction may have influence on functional ability (FA). It was still unclear how ...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-023-04089-5
Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight et al. • BMJ Open
(2023)
Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the un...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjopen-2023-077772
Yan Zhao, Tingting Chen, Conghua Ji, Yuxin Shang et al. • Experimental Gerontology
(2026)
Background: Stroke is an independent risk factor for heart failure (HF), and they are both linked to systemic inflammation. The neutrophil-percentage-to-albumin ratio (NPAR) is a novel inflammation biomarker. However, it is unclear whether ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2025.113010
Erden Eren, Jeannie-Marie Leoutsakos, Juan Troncoso, Constantine G. Lyketsos et al. • Cells
(2022)
The hallmarks of Alzheimer’s disease (AD) pathology are senile plaques containing amyloid-beta (Aβ) and neurofibrillary tangles containing hyperphosphorylated tau. Additional pathologies often co-exist, whereas multiple pathogenic mechanism...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cells11030436
Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen et al. • BMC Geriatrics
(2025)
Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. Due to their frailty status, comorbidity burden can serve as a useful predictive indicator of vul...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-025-05721-2
Amira Al Balakosy, Mostafa Alfishawy, Omnia Elnabawy, Azza Hassan et al. • Afro-Egyptian Journal of Infectious and Endemic Diseases
(2021)
Background and study aim: Epidemiological data reported lower death rates of COVID-19 cases in countries with higher & recent coverage by measles containing vaccines. In this study we aim to identify measles IgG titer in COVID-1...
DOAJ
Open Access (DOAJ)
DOI: 10.21608/aeji.2021.72615.1144
Ling Tong, Zhe Cong, Long Tian, Jingjing Zhang et al. • Frontiers in Microbiology
(2021)
It is challenging to trace the complicated individual-based variations of HIV-specific immunocompetence shift during the successful antiretroviral therapy (ART) era. Using eight rhesus monkeys simulating a longitudinal stage-dependent cohor...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmicb.2021.704449
Jin Guo, Andrew Wister, Barbara Mitchell, Merril Silverstein et al. • BMC Geriatrics
(2026)
Abstract Objectives Based on defamilization, individualization, and contingent intergenerational solidarity theories, this study developed a cultural defamilization framework. Longitudinal data were used to explore changes in the associatio...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-026-07449-z
Tetsuro Tago, Jun Toyohara • Molecules
(2018)
Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules23020300