Academic Articles & Research Papers

Mathematical analysis

Mathematics and Indispensability

Mathematics plays an indispensable role in the explanations that modern science provides of empirical phenomena. From this unexceptionable observation, a controversial philosophical conclusion is sometimes drawn. The claim is advanced that ...

Superconformal indices of N $$ \mathcal{N} $$ = 4 Chern-Simons matter theories

Abstract Gaiotto and Witten found that one can construct 3d N $$ \mathcal{N} $$ = 4 Chern-Simons matter theories by using N $$ \mathcal{N} $$ = 4 SCFT whose momentum map of global symmetries satisfy special condition. Usually, one uses free...

AMPLITUDE-TIME ANALYSIS OF BIOMECHANICAL PATTERNS OF HUMAN MOTIONS

Biomechanical analysis of motions solves the tasks of efficiency estimation of movement realization, search of technique optimal variants and tactics of motion performance, definition of a degree and reasons of not matching real movement ac...

An Introduction to Mathematical Logic

Logic, the systematic study of reasoning, is one of the oldest branches of mathematics. For example, the notion of a syllogism was important to the ancient Greeks, and the phrase “Aristotelian logic” is still commonly used. But the flowering...

Domains in Health Technology Assessment of Digital Health Technologies: A Mapping Review

OBJECTIVES: Health Technology Assessment (HTA) plays an important role in evaluating digital health technologies (DHTs) to inform decision making. Commonly used HTA frameworks have been criticized as inadequate for assessing DHTs leading to...

The economics of TAVI: A systematic review

Objective: The scope of this systematic review is to update the existing body of evidence regarding the cost-effectiveness of transcatheter aortic valve implantation, stratified across all risk categories, and to assess their methodological...

Essential requirement of complex number for oscillatory phenomenon in intracellular trafficking process

Intracellular protein trafficking processes consisting of three intracellular states are described by three differential equations. To solve the equations, a quadratic equation is required, and its roots are generally real or complex. The p...

Epidermal Growth Factor Induces Vasoconstriction Through the Phosphatidylinositol 3-Kinase-Mediated Mitogen-Activated Protein Kinase Pathway in Hypertensive Rats

Abstract.: We investigated whether increased contractile responsiveness to epidermal growth factor (EGF) is associated with altered activation of mitogen-activated protein kinase (MAPK) in the aortic smooth muscle of deoxycorticosterone ace...

Gallium nanoparticles along with low-dose gamma radiation modulate TGF-β/MMP-9 expression in hepatocellular carcinogenesis in rats

Combining chemotherapy with radiotherapy potentiates the outcome of cancer treatment for the more comprehensive attack. In the current study, we continued to assess the therapeutic efficaciousness of the newly synthesized gallium nanopartic...

Neurological Manifestations of SARS-CoV-2 Infection: Protocol for a Sub-analysis of the COVID-19 Critical Care Consortium Observational Study

IntroductionNeurological manifestations and complications in coronavirus disease-2019 (COVID-19) patients are frequent. Prior studies suggested a possible association between neurological complications and fatal outcome, as well as the exis...

Dietary Supplementation with the Red Seaweed <i>Porphyra umbilicalis</i> Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice

Some diet profiles are associated with the risk of developing cancer; however, some nutrients show protective effects. Porphyra umbilicalis is widely consumed, having a balanced nutritional profile; however, its potential for cancer chemopr...

Neurotoxicity of PM_2.5-Bound Multi-Pollutant Mixtures in Parkinson’s Disease: Exploring the <i>INPP5D</i>/SHIP1-PI3K-AKT Axis via an Integrative Multi-Omics Study

Accumulating epidemiological evidence links ambient PM2.5 exposure to elevated Parkinson’s disease (PD) risk, yet the neurotoxicity triggered by PM2.5 multi-pollutant mixtures under real co-exposure scenarios remains insufficiently elucidat...

Treatment of Gluteal Tendinopathy: A Systematic Review and Stage-Adjusted Treatment Recommendation

Background: Gluteal tendinopathy is the most common lower limb tendinopathy. It presents with varying severity but may cause debilitating lateral hip pain. Purpose: To review the therapeutic options for different stages of gluteal tendinopa...

Evaluating stool microbiome integrity after domestic freezer storage using whole-metagenome sequencing, genome assembly, and antimicrobial resistance gene analysis

ABSTRACT The gut microbiome is crucial for host health. Early childhood is a critical period for the development of a healthy gut microbiome, but it is particularly sensitive to external influences. Recent research has focused on using adva...

ANTIFUNGAL Trycophyton rubrum AND Trycophyton mentagrophytes IN LIQUID BATH SOAP FERMENTED PROBIOTIC KOMBUCHA FLOWER TELANG (Clitoria ternatea L) AS A PHARMACEUTICAL BIOTECHNOLOGY PRODUCT

Telang flower kombucha (Clitoria ternatea L) is a functional probiotic drink that has antifungal properties. This study aimed to examine the antifungal activity of the probiotic bath soap formulation fermented kombucha telang flower against...

Detection and genetic diversity of Wolbachia and its associated prophage WO in mosquito populations from Ethiopia

Abstract Arboviral diseases transmitted by mosquitoes, including dengue, Chikungunya, Zika, yellow fever, West Nile virus (WNV), and Rift Valley fever (RVF), pose a significant public health challenge globally, particularly impacting popula...

Postbiotics: From emerging concept to application

The microbiome innovation has resulted in an umbrella term, postbiotics, which refers to non-viable microbial cells, metabolic byproducts and their microbial components released after lysis. Postbiotics, modulate immune response, gene expre...

Early disc degeneration in radiotherapy-treated childhood brain tumor survivors

Abstract Background Childhood brain tumor (BT) survivors have an increased risk of treatment-related late effects, which can reduce health-related quality of life and increase morbidity. This study aimed to investigate lumbar disc degenerat...

3D-Printed GelMA Microneedles with Multilayer Therapeutic Properties for Diabetic Wound-Relevant Drug Delivery