Academic Articles & Research Papers

Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study

Background: Endothelial dysfunction has a key role in the pathogenesis of coronavirus disease 2019 (COVID-19) and its disabling complications. We designed a case-control study to assess the alterations of endothelium-dependent flow-mediated...

Enhancement of doxorubicin anti-cancer activity by vascular targeting using IsoDGR/cytokine-coated nanogold

Abstract Background Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature. We prepared bi- o...

Stem Cell Technology in Medical Biotechnology

Assessment of the medical biotechnology industry in Singapore.

Seeing the industry’s promising future, Singapore has aimed to developed biotechnology as the fourth pillar of the economy (Ministry of Trade, 2000). Thus, this research work assesses the strength, weaknesses and competitive advantage of th...

Computational Tools; Indispensable Armamentarium of Medical Biotechnology

Objective: Computational infrastructure of medical biotechnology provides insight into elements of genomics, proteomics for understanding diseases and biological systems in a more comprehensive and systematic way. The present study exclusiv...

Students' knowledge of, and attitudes towards biotechnology revisited, 1995–2014: Changes in agriculture biotechnology but not in medical biotechnology

Modern biotechnology is one of the most important scientific and technological revolutions in the 21st century, with an increasing and measurable impact on society. Development of biotechnology curriculum has become important to high school...

Medical Biotechnology, Biopharmaceutics, Forensic Science and Bioinformatics

Clinical Laboratory Diagnostics and Medical Biotechnology: Principles and Applications

Buy Clinical Laboratory Diagnostics and Medical Biotechnology: Principles and Applications written by Zainab Falah Hassan Jassim, Raghad Kamel Taima Taha, Aseel Adnan Mahdi Hamad, Nour Mohsen Habib Hulw and Zainab Abbas Aghajan Shira at low...

Research ethics and the development of medical biotechnology

Commercial funding is of most importance for the development of new biomedical technologies such as xenotransplantation. The dependence of such funding may, however, carry certain risks from an ethical point of view. In this article some of...

Current status of medical biotechnology in Malaysia.

In recent years medical research, utilising biotechnology and related tools, has contributed significantly to advances in the laboratory diagnosis of infectious diseases and hormonal disorders in Malaysia, The main thrust was in the develop...

Use of CRISPR-Cas Technology in Medical Biotechnology

Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing technology won the 2020 Nobel prize in chemistry. CRISPR was discovered in the genome of prokaryotes, where it functions as their adaptive immune system. E...

Convergent Adaptation in the Dominant Global Hospital Clone ST239 of Methicillin-Resistant <named-content content-type="genus-species">Staphylococcus aureus</named-content>

ABSTRACT Infections caused by highly successful clones of hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) are a major public health burden. The globally dominant sequence type 239 (ST239) HA-MRSA clone has persiste...

Antibacterial and antioxidant effects of Punicalagin extracts from Punica granatum peels

The growing recognition of the health-promoting potential of compounds derived from natural sources, particularly those exhibiting antimicrobial and antioxidant activities, has resulted in a surge of research publications dedicated to explo...

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

Abstract The SARS-CoV-2 virus caused the most severe pandemic around the world, and vaccine development for urgent use became a crucial issue. Inactivated virus formulated vaccines such as Hepatitis A and smallpox proved to be reliable appr...

Formation and stability of oil-in-water nanoemulsions containing rice bran oil: <it>in vitro </it>and <it>in vivo </it>assessments

Abstract Background Nanoemulsions have practical application in a multitude of commercial areas, such as the chemical, pharmaceutical and cosmetic industries. Cosmetic industries use rice bran oil in sunscreen formulations, anti ageing prod...

CD36‐Binding Amphiphilic Nanoparticles for Attenuation of α‐Synuclein‐Induced Microglial Activation

Neuroinflammation is one of the hallmarks contributing to Parkinson's disease (PD) pathology, where microglial activation occurs as one of the earliest events, triggered by extracellular α‐synuclein (aSYN) binding to the cluster of differen...

Peptide-functionalized periodic mesoporous silica nanoparticles for monocyte-specific TET3 Silencing enhance cardiac repair after acute myocardial infarction

Abstract Modulating the balance between pro- and anti-inflammatory monocyte subsets holds therapeutic promise in acute myocardial infarction (AMI); however, effective and selective strategies are still lacking. In this study, we are the fir...

Optimally biosynthesized, PEGylated gold nanoparticles functionalized with quercetin and camptothecin enhance potential anti-inflammatory, anti-cancer and anti-angiogenic activities

Abstract Background The development of nano delivery systems is rapidly emerging area of nanotechnology applications where nanomaterials (NMs) are employed to deliver therapeutic agents to specific site in a controlled manner. To accomplish...

High level non-carbapenemase carbapenem resistance by overlaying mutations of mexR, oprD, and ftsI in Pseudomonas aeruginosa

ABSTRACT Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global threat, but the mechanism of non-carbapenemase carbapenem resistance is still unclear. In the current study, we investigated the contributions of point mutations in mex...

Bioremediation of Persistent Organic Pollutant—Oxybenzone with <i>Pleurotus djamor</i>

Oxybenzone, a common sunscreen ingredient, has been widely detected in various environmental matrices, posing significant ecological and health risks. The present study demonstrates, for the first time, the capacity of Pleurotus djamor to d...