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Showing 20 of 877 academic articles

Total Lymphocyte Count, Neutrophil-Lymphocyte Ratio, and Platelet-Lymphocyte Ratio as Prognostic Factors in Advanced Non-Small Cell Lung Cancer with Chemoradiotherapy [Corrigenudm]

Song X, Chen D, Yuan M, Wang H et al. • Cancer Management and Research (2021)

Song X, Chen D, Yuan M, Wang H, Wang Z. Cancer Manag. 2018;10:6677– 6683On page 6677, Abstract, Results subheading, the median baseline PLR should be 136.1.On page 6680, Results section, 2nd paragraph, the median baseli...

DOAJ Open Access (DOAJ)

Development and validation of an online dynamic nomogram based on the atherogenic index of plasma to screen nonalcoholic fatty liver disease

Hewei Peng, Junchao Zhang, Xianhua Huang, Miao Xu et al. • Lipids in Health and Disease (2023)

Abstract Background Nonalcoholic fatty liver disease (NAFLD), a common liver disease worldwide, can be reversed early in life with lifestyle and medical interventions. This study aimed to develop a noninvasive tool to screen NAFLD accuratel...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12944-023-01808-0

Establishment of a Pre-vascularized 3D Lung Cancer Model in Fibrin Gel—Influence of Hypoxia and Cancer-Specific Therapeutics

Caroline Kniebs, Caroline Kniebs, Anja Elisabeth Luengen, Anja Elisabeth Luengen et al. • Frontiers in Bioengineering and Biotechnology (2021)

Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mortality. In order to understand the disease and to develop new treatments, in vitro human lung cancer model systems which imitate the physio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2021.761846

CircUCK2(2,3) promotes cancer progression and enhances synergistic cytotoxicity of lenvatinib with EGFR inhibitors via activating CNIH4–TGFα–EGFR signaling

Xindong Wei, Anfeng Si, Shuai Zhao, Yi Fu et al. • Cellular & Molecular Biology Letters (2025)

Abstract Background Circular (circ)RNAs have emerged as crucial contributors to cancer progression. Nonetheless, the expression regulation, biological functions, and underlying mechanisms of circRNAs in mediating hepatocellular carcinoma (H...

DOAJ Open Access (DOAJ) DOI: 10.1186/s11658-025-00690-1

Confined migration induces heterochromatin formation and alters chromatin accessibility

Chieh-Ren Hsia, Jawuanna McAllister, Ovais Hasan, Julius Judd et al. • iScience (2022)

Summary: During migration, cells often squeeze through small constrictions, requiring extensive deformation. We hypothesized that nuclear deformation associated with such confined migration could alter chromatin organization and function. B...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.isci.2022.104978

Unrevealing the dual role of paired box and sex determining region Y related high mobility group box in glioblastoma

Kallol Polley, Sayed Mohammed Firdous • Discover Oncology (2026)

Abstract This narrative review summarises glioblastoma (GBM), a very frequent invasive kind of brain tumour in the elderly that is extremely aggressive, resistant to treatment, and has a bad prognosis because of its substantial genetic and ...

DOAJ Open Access (DOAJ) DOI: 10.1007/s12672-026-04671-4

USP1-trapping lesions as a source of DNA replication stress and genomic instability

Kate E. Coleman, Yandong Yin, Sarah Kit Leng Lui, Sarah Keegan et al. • Nature Communications (2022)

Here the authors provide mechanistic insights into how auto-cleavage of the USP1 deubiquitinase regulates DNA replication and genome stability. Implications for the targeting of USP1 activity via protein-DNA trapping in cancer therapy are d...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-022-29369-3

Graphs in molecular biology

Wolfgang K. Huber, Vincent J. Carey, Long Li, Seth Falcon et al. • BMC Bioinformatics (2007)

Graph theoretical concepts are useful for the description and analysis of interactions and relationships in biological systems. We give a brief introduction into some of the concepts and their areas of application in molecular biology. We d...

OPENALEX cc-by DOI: https://doi.org/10.1186/1471-2105-8-s6-s8 PMC: 1995545

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome

Florian Köhler, Felix Bormann, Günter Raddatz, Julian Gutekunst et al. • Genome Medicine (2020)

Abstract Background Hutchinson-Gilford progeria syndrome (HGPS) is a progeroid disease characterized by the early onset of age-related phenotypes including arthritis, loss of body fat and hair, and atherosclerosis. Cells from affected indiv...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13073-020-00749-y

Molecular Biology of the Cell

Bruce Alberts, Alexander D. Johnson, Julian Herman Lewis, MARTIN C. RAFF et al. • W.W. Norton eBooks (2007)

For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advan...

OPENALEX DOI: https://doi.org/10.1201/9780203833445

Nanotechnology for the biologist

Scott E. McNeil • Journal of Leukocyte Biology (2005)

Nanotechnology refers to research and technology development at the atomic, molecular, and macromolecular scale, leading to the controlled manipulation and study of structures and devices with length scales in the 1- to 100-nanometers range...

OPENALEX DOI: https://doi.org/10.1189/jlb.0205074

Tumor probability mapping of fluorescence intensity during image-guided surgery of head and neck cancer

Akhilesh M Wodeyar, Sherin James, Benjamin B. Kasten, Nicolaus D. Knight et al. • Scientific Reports (2026)

Abstract Achieving negative surgical margins remains a critical determinant of local recurrence and survival in head and neck cancer (HNC) surgery. Current intraoperative margin assessment techniques, including frozen section analysis, suff...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-026-56078-4