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The importance of reproductive health education for elementary school children: Long-term benefits and challenges in implementation - A literature review

Musthamin Balumbi, Stang Stang, Suriah Suriah, Syarifuddin Syarif et al. • Journal of Education and Health Promotion (2025)

Reproductive health education at the primary school level is a controversial topic. Although some recognize its importance in providing accurate information about the body and development, others raise concerns about cultural sensitivities ...

DOAJ Open Access (DOAJ) DOI: 10.4103/jehp.jehp_861_24

New Directions in Chronic Disease Management

Hun-Sung Kim, Jae-Hyoung Cho, Kun-Ho Yoon • Endocrinology and Metabolism (2015)

A worldwide epidemic of chronic disease, and complications thereof, is underway, with no sign of abatement. Healthcare costs have increased tremendously, principally because of the need to treat chronic complications of non-communicable dis...

DOAJ Open Access (DOAJ) DOI: 10.3803/EnM.2015.30.2.159

Effectiveness and cost-effectiveness of community perinatal mental health services on access, experience, recovery/relapse and obstetric and neonate outcomes: the ESMI-II mixed-methods study

Heather O’Mahen, Louise Howard, Helen Sharp, Antoinette Davey et al. • Health and Social Care Delivery Research (2025)

Background Perinatal mental health disorders affect one in five mothers during pregnancy or within 2 years post childbirth. These disorders can lead to poor pregnancy and childbirth outcomes and maternal deaths. Additionally, they negativel...

DOAJ Open Access (DOAJ) DOI: 10.3310/RRAP0011

Two Sides of the Same Coin—Mechanistic Insight, Diagnostic Application and Therapeutic Translation of Bacterial and Host‐Derived Extracellular Vesicles

Philipp Arnold, Fanni Annamária Boros, Jochen Mattner, Gerald Seidel et al. • Journal of Extracellular Biology (2025)

ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellu...

DOAJ Open Access (DOAJ) DOI: 10.1002/jex2.70093

Knowledge, attitude, and practices toward COVID-19 vaccination among patients attending OPD of a tertiary care hospital in Kolkata: A descriptive cross-sectional study

Agnij Bhattacharyya, Debadatta Chakrabarty, Anindya Mukherjee, Soumitra Mondal • National Journal of Physiology, Pharmacy and Pharmacology (2024)

Background: The acceptance of the coronavirus disease 2019 (COVID-19) vaccination by the community was largely affected by information or misinformation spreading through various channels. Hence, in the process of deploying vaccines, it bec...

DOAJ Open Access (DOAJ) DOI: 10.5455/njppp.2023.13.10495202320112023

Segmentation Clock Networks in Vertebrate Somitogenesis

SUN Qing, WANG Yu, CUO-A Jian, HAO Yan et al. • Shengwu huaxue yu shengwu wuli jinzhan (2024)

In vertebrate embryonic development, the segmentation clock controls the cyclic formation of somites through presomitic mesoderm (PSM) cells. Somites are paired segmented structures along the anterior-posterior axis that eventually develop ...

DOAJ Open Access (DOAJ) DOI: 10.16476/j.pibb.2023.0231

Therapist-Supported Online Interventions for Children and Young People With Tic Disorders: Lessons Learned From a Randomized Controlled Trial and Considerations for Future Practice

Chamberlain, Liam R, Hall, Charlotte L, Andrén, Per, Davies, E Bethan et al. • JMIR Mental Health (2020)

In recent years, research into internet-based cognitive behavioral therapy (iCBT) has suggested that therapist-guided digital interventions have greater engagement, adherence, and effectiveness than self-directed digital therapies. While re...

DOAJ Open Access (DOAJ) DOI: 10.2196/19600

Preeclampsia impedes foetal kidney development by delivering placenta-derived exosomes to glomerular endothelial cells

Mengqi Gu, Pengzheng Chen, Dongmei Zeng, Xiaotong Jiang et al. • Cell Communication and Signaling (2023)

Abstract Background Foetal renal dysplasia is still the main cause of adult renal disease. Placenta-derived exosomes are an important communication tool, and they may play an important role in placental (both foetal and maternal) function. ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12964-023-01286-y

CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression

Wei Yan, Guo-hui Xiao, Li-juan Wang, Yan Zhou et al. • Journal of Translational Medicine (2025)

Abstract Background The stiffness of the matrix is closely related to the progression of hepatocellular carcinoma (HCC). Although direct targeting of stromal rigidity in HCC remains a clinical challenge, cancer-associated fibroblasts (CAFs)...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-025-06325-5

What types of tobacco control public service advertisements work for Chinese adolescents? A mixed-methods study

Yu Chen<sup>*+</sup>, Haoyi Liu<sup>*+</sup>, Shiyu Liu<sup>*+</sup>, Yujiang Cai et al. • Tobacco Induced Diseases (2025)

Introduction Adolescent tobacco use has become a serious global public health problem, and effective tobacco control public service advertisements (PSAs) are crucial for reducing adolescent smoking rates. The study aims to employ a mixedmet...

DOAJ Open Access (DOAJ) DOI: 10.18332/tid/211650

Practical Recommendations for Supporting a Systems Biology Cyberinfrastructure

Jeremy D. DeBarry, Jessica C. Kissinger, Mustafa V. Nural, Suman B. Pakala et al. • Data Science Journal (2020)

Projects in the life sciences continue to increase in complexity as they scale to answer deeper and more diverse questions. They employ technologies that generate increasingly large ‘omic’ datasets and research teams regularly include exper...

DOAJ Open Access (DOAJ) DOI: 10.5334/dsj-2020-024

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T. Malivanova, E. Skoromyslova, N. Mazurenko • EJC Supplements (2015)

Tumor necrosis factor alpha (TNF) is a multifunctional cytokine, which possesses various biologic functions depending on the type of the cells and the physiological context. TNF is synthesized by immune cells as well as malignant cells. Acc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ejcsup.2015.08.063

Evaluating the diagnostic value and prospects of genomic and mutational sequencing in malignant transformation of oral leukoplakia

Jian Yuan, Yuhan Zhu, Zirui Wang, Zhongjing Lv et al. • Journal of Dental Sciences (2025)

Genomic and mutational sequencing in malignant transformation of oral leukoplakia (OLK) has emergingly gained momentum. In this short communication, we identified 5 retrospective follow-up studies and 5 cross-section comparative studies on ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jds.2025.07.016

Legionella shows a diverse secondary metabolism dependent on a broad spectrum Sfp-type phosphopantetheinyl transferase

Nicholas J. Tobias, Tilman Ahrendt, Ursula Schell, Melissa Miltenberger et al. • PeerJ (2016)

Several members of the genus Legionella cause Legionnaires’ disease, a potentially debilitating form of pneumonia. Studies frequently focus on the abundant number of virulence factors present in this genus. However, what is often overlooked...

DOAJ Open Access (DOAJ) DOI: 10.7717/peerj.2720

Extracellular vesicles: A dive into their role in the tumor microenvironment and cancer progression

Kassandra Lopez, Seigmund Wai Tsuen Lai, Edwin De Jesus Lopez Gonzalez, Raúl G. Dávila et al. • Frontiers in Cell and Developmental Biology (2023)

Extracellular vesicles (EVs) encompass a diverse set of membrane-derived particles released from cells and are found in numerous biological matrices and the extracellular space. Specific classes of EVs include apoptotic bodies, exosomes, an...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcell.2023.1154576

Spatio-temporal analysis of childhood vaccine uptake in Nigeria: a hierarchical Bayesian Zero-inflated Poisson approach

Temitayo Victor Lawal, Kehinde Adebola Atoloye, Ayo Stephen Adebowale, Adeniyi Francis Fagbamigbe • BMC Pediatrics (2023)

Abstract Background Globally, child mortality and morbidity remain a serious health challenge and infectious diseases are the leading causes. The use of count models together with spatial analysis of the number of doses of childhood vaccine...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12887-023-04300-x

ASPECTOS CLÍNICOS, EPIDEMIOLÓGICOS E LABORATORIAIS DE PORTADORES DE TUBERCULOSE PULMONAR E EXTRAPULMONAR PROVENIENTES DE SERVIÇOS PÚBLICOS DO ESTADO DE PERNAMBUCO

Renata Inglez de Souza Tej, Lilian Maria Lapa Montenegro, Wlisses Henrique Veloso de Carvalho Silva, Jéssica Lopes Teixeira et al. • Brazilian Journal of Infectious Diseases (2023)

Introdução/objetivo: A tuberculose (TB) mantém-se como um grave problema de saúde pública, sendo a principal causa de morte por doença infecciosa antes da COVID-19. Em 2022, foram notificados 78.057 novos casos de TB no Brasil, destes, 5.14...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.bjid.2023.103607

Patient-Reported Continued Benefits in Patients Treated with Pexidartinib for Tenosynovial Giant Cell Tumor Based on a Real-World Study in the United States

Margaret Wooddell PhD, MBA, Dong Dai PhD, Feng Lin PhD, Irene Pan MS et al. • Foot & Ankle Orthopaedics (2024)

Category: Other Introduction/Purpose: Tenosynovial giant cell tumors (TGCT) are neoplastic, inflammatory lesions that arise within the synovium and can be locally aggressive. Patients with TGCT frequently experience pain and joint swelling,...

DOAJ Open Access (DOAJ) DOI: 10.1177/2473011424S00422