Academic Articles & Research Papers

Injury death certificates without specification of the circumstances leading to the fatal injury – the Norwegian Cause of Death Registry 2005–2014

Abstract Background For injury deaths, the underlying cause of death is defined as the circumstances leading to the injury. When this information is missing, the ICD-10 code X59 (Exposure to unspecified factor) is used. Lack of knowledge of...

Electronic Cigarette Use Is Not Associated with COVID-19 Diagnosis

This analysis tested the hypothesis that current e-cigarette use was associated with an increased risk of SARS-CoV-2 infection in patients seeking medical care. E-cigarette and conventional cigarette use were ascertained using a novel elect...

Comparison of the effectiveness of an oral combination of thiamine, pyridoxine, and cyanocobalamin with parenteral cyanocobalamin in adolescents with nutritional vitamin B12 deficiency

Aims: Nutritional vitamin B12 deficiency remains a significant public health issue. This study aimed to compare the efficacy of an oral combination of thiamine, pyridoxine, cyanocobalamin, and parenteral cyanocobalamin treatment among adole...

Evolution of Trends in European Medical Informatics

This presentation attempts to analyze the trends in Medical Informatics along half a century, in the European socio-political and technological development context. Based on the major characteristics which seem dominant in some periods, a s...

Medical informatics across Europe: Analysis of medical informatics scientific output in 33 European countries

OBJECTIVES: To investigate the medical informatics scientific output in 33 European countries. METHODS: Medical Subject Heading term "medical informatics" was used to identify all relevant articles published in 1998-2007 and indexed in the ...

Quantum computing in medical informatics

In an era of exponential technological advancements, the integration of quantum computing (QC) and medical informatics emerges as a captivating frontier, promising to unlock a new realm of possibilities for healthcare. QC, harnessing the pr...

[Medical informatics].

(Bio)Medical Informatics in the Next Decade

Even though medical informatics is most often viewed from the perspective of its host disciplines in clinical and biologic medicine, it has an identity and agenda of its own. This paper is an attempt to promote discussion about the long-ter...

Performance of computational algorithms to deconvolve heterogeneous bulk ovarian tumor tissue depends on experimental factors

Abstract Background Single-cell gene expression profiling provides unique opportunities to understand tumor heterogeneity and the tumor microenvironment. Because of cost and feasibility, profiling bulk tumors remains the primary population-...

The effect of structured medication review followed by face-to-face feedback to prescribers on adverse drug events recognition and prevention in older inpatients – a multicenter interrupted time series study

Abstract Background The effectiveness of interventions to improve medication safety in older inpatients is unclear, given a paucity of properly designed intervention studies applying clinically relevant endpoints such as hospital-acquired p...

AI-based disease risk score for community-acquired pneumonia hospitalization

Summary: Community-acquired pneumonia (CAP) is an acute infection involving the parenchyma of the lungs, which is acquired outside of the hospital. Population-wide real-world data and artificial intelligence (AI) were used to develop a dise...

Optimal@NRW: optimized acute care of nursing home residents using an intersectoral telemedical cooperation network — study protocol for a stepped-wedge trial

Abstract Background Increasing life expectancy is associated with a growing number of people living in nursing homes, while the availability of outpatient medical care, especially from family doctors, is stagnating in this sector. Consequen...

The Reconnecting the Hand and Arm with Brain (ReHAB) Commentary on “An Integrated Brain-Machine Interface Platform With Thousands of Channels”

Intracortical brain-machine interfaces are a promising technology for allowing people with chronic and severe neurological disorders that resulted in loss of function to potentially regain those functions through neuroprosthetic devices. Th...

Pitfalls in the use of whole slide imaging for the diagnosis of central nervous system tumors: A pilot study in surgical neuropathology

Background: Whole slide imaging (WSI) finds increasingly higher value in everyday surgical pathology in addition to its well-established use for educational and research purposes. However, its diagnostic utility, especially in subspecialty ...

Behavioral dataset for Long-Evans and its schizophrenia-like substrain through several generations

Abstract We present a high-throughput behavioral dataset acquired with Ambitus, an automated reward-based corridor system that records locomotor and exploratory activities and cognitive functions after minimal handling. The collection conta...

Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt

Abstract Background Many cancers arise from mutations in cells within epithelial tissues. Mutations manifesting at the subcellular level influence the structure and function of the tissue resulting in cancer. Previous work has proposed how ...

Caring for Computers: The Hidden Work of Clinical Nurses during the Introduction of Health Information Systems in a Teaching Hospital in Taiwan

Implementing health information systems for enhancing patient care and management occurs worldwide. Discovering how nurses, as important system end-users, experience technology-reliant clinical practice involved focus groups (n = 25) and in...

Understanding tinnitus symptom dynamics and clinical improvement through intensive longitudinal data

Abstract Intensive longitudinal sampling enhances subjective data collection by capturing real-time, dynamic inputs in natural settings, complementing traditional methods. This study evaluates the feasibility of using daily self-reported ap...

Structural dataset for the PPARγ V290M mutant

Loss-of-function mutation V290M in the ligand-binding domain of the peroxisome proliferator activated receptor γ (PPARγ) is associated with a ligand resistance syndrome (PLRS), characterized by partial lipodystrophy and severe insulin resis...

Cross-cultural adaptation and psychometric properties of the Kessler Scale of Psychological Distress to a traumatic brain injury population in Swahili and the Tanzanian Setting

Abstract Background To evaluate the psychometric properties of a Swahili version of the Kessler Psychological Distress scale in an injury population in Tanzania. Methods Swahili version of the Kessler Psychological Distress scale was develo...