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Academic Articles & Research Papers
Showing 20 of 3,783 academic articles
Lauren M. Herr, Swagata Mukhopadhyay, Olivia M. Anderson, Tucker H. Couch et al. • Communications Biology
(2026)
Abstract DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary structures that present a substant...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s42003-026-09966-4
Junqi Yang, Yumin Ma, Jiang Liu, Qingtian Zhu et al. • Experimental Gerontology
(2024)
The aging of pancreatic beta cells is closely associated with various diseases, such as impaired glucose tolerance, yet the underlying regulatory mechanisms remain unclear. In this study, we screened young and aged mouse pancreatic beta cel...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2024.112633
Luciano Magalhães Vitorino BSN, MSc, Gail Low RN, BSN, MA, PhD, Lucila Amaral Carneiro Vianna PhD • Gerontology and Geriatric Medicine
(2016)
Objective: This study examined the effect of Positive and Negative Spiritual and Religious Coping (SRC) upon older Brazilian’s quality of life (QOL). Method: A secondary analysis of data collected from 77 nursing home residents (NHRs; M age...
DOAJ
Open Access (DOAJ)
DOI: 10.1177/2333721416658140
Yan Zhao, Tingting Chen, Conghua Ji, Yuxin Shang et al. • Experimental Gerontology
(2026)
Background: Stroke is an independent risk factor for heart failure (HF), and they are both linked to systemic inflammation. The neutrophil-percentage-to-albumin ratio (NPAR) is a novel inflammation biomarker. However, it is unclear whether ...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.exger.2025.113010
Hiroshi Murayama, Benjamin A. Shaw • Journal of Obesity & Metabolic Syndrome
(2017)
This article reviewed studies to investigate the association between trajectories of body mass index (BMI) and mortality among older adults. Investigators conducted a systematic search of published peer-reviewed literature in the PubMed dat...
DOAJ
Open Access (DOAJ)
DOI: 10.7570/jomes.2017.26.3.181
Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen et al. • BMC Geriatrics
(2025)
Abstract Background During the COVID-19 pandemic, nursing home (NH) residents faced the highest risk of severe COVID-19 disease and mortality. Due to their frailty status, comorbidity burden can serve as a useful predictive indicator of vul...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-025-05721-2
Anna Maria Cybulska, Ewa Kupcewicz, Kamila Rachubińska, Mariusz Panczyk et al. • Frontiers in Public Health
(2025)
BackgroundNursing students frequently encounter stressful and demanding situations during clinical training, which may hinder their well-being and professional development. A strong sense of coherence is thought to buffer the negative effec...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fpubh.2025.1713759
Ling Tong, Zhe Cong, Long Tian, Jingjing Zhang et al. • Frontiers in Microbiology
(2021)
It is challenging to trace the complicated individual-based variations of HIV-specific immunocompetence shift during the successful antiretroviral therapy (ART) era. Using eight rhesus monkeys simulating a longitudinal stage-dependent cohor...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmicb.2021.704449
Jin Guo, Andrew Wister, Barbara Mitchell, Merril Silverstein et al. • BMC Geriatrics
(2026)
Abstract Objectives Based on defamilization, individualization, and contingent intergenerational solidarity theories, this study developed a cultural defamilization framework. Longitudinal data were used to explore changes in the associatio...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12877-026-07449-z
Tetsuro Tago, Jun Toyohara • Molecules
(2018)
Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules23020300
Martha Holstein, Meredith Minkler • The Gerontologist
(2003)
The "new gerontology," built on the concept of successful aging, sets forth the preconditions for and the end product of the process of aging successfully. Focused on health and active participation in life, it vests largely within individu...
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DOI: https://doi.org/10.1093/geront/43.6.787
Huaqi Zhao, Songnan Zhang, Xiang Peng, Zhengguang Lu et al. • Frontiers in Neurorobotics
(2025)
Object detection is a critical component in the development of autonomous driving technology and has demonstrated significant growth potential. To address the limitations of current techniques, this paper presents an improved object detecti...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fnbot.2024.1484276
Exsaris Januar, Nurhizrah Gistituati, Yanti Fitria, Alwen Bentri et al. • Educational Process: International Journal
(2025)
Background/purpose. Study addresses the problem of low scientific and digital literacy among Grade 6 students (Phase C) in the IPAS (Science and Social Studies) subject under the Merdeka Curriculum, particularly in the theme “Our Endangered...
DOAJ
Open Access (DOAJ)
DOI: 10.22521/edupij.2025.18.450
Shuping Wang, Pengcheng Chen, Xiaozhen Jing, Jinglin Zou et al. • Materials & Design
(2026)
STING agonist-based immunotherapy holds considerable promise for cancer treatment, yet its efficacy against immunologically “cold” tumors such as lung adenocarcinoma (LUAD) remains markedly limited. A major obstacle lies in the highly glyco...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.matdes.2026.117182
Shabir Ahmad, Salma Haque, Khalid Ali Khan, Nabil Mlaiki • Fractal and Fractional
(2023)
In this study, we analyze the transmission of the COVID-19 model by using a piecewise operator in the classical Caputo sense. The existence along with the uniqueness of the solution of the COVID-19 model under a piecewise derivative is pres...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/fractalfract7070501
Qian Yin, Xinxin Nie, Jiangyu Wu, Qi Wang et al. • International Journal of Mining Science and Technology
(2023)
A fractal model governing saw-tooth fractures was first introduced to replicate sandstone samples containing an inclined 3D penetrating rough fracture surface with various joint roughness coefficients (JRC). In conventional triaxial compres...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ijmst.2023.02.002
Qiyuan Dai, Liang Ma, Li Li, Guangjun Tian • Results in Physics
(2023)
Using finite element calculations, we investigated the near field properties of two types of commonly used metal nanostructures (a tip-substrate model representing a scanning tunneling microscope type setup (TS) and a nanoparticle-on-mirror...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.rinp.2023.106360
CA (United States) Lawrence Livermore National Lab., D Lesuer, USDOE, Washington, DC (United States) (1997)
During FY-96, work within the Materials Science and Engineering Thrust Area was focused on material modeling. Our motivation for this work is to develop the capability to study the structural response of materials as well as material proces...
OPENALEX
Open Access
DOI: https://doi.org/10.2172/623044
Xiaoting Zhong, Brian J. Gallagher, Shusen Liu, Bhavya Kailkhura et al. • npj Computational Materials
(2022)
Abstract Machine learning models are increasingly used in materials studies because of their exceptional accuracy. However, the most accurate machine learning models are usually difficult to explain. Remedies to this problem lie in explaina...
OPENALEX
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DOI: https://doi.org/10.1038/s41524-022-00884-7
Ingo Steinbach • Modelling and Simulation in Materials Science and Engineering
(2009)
The phase-field method is reviewed against its historical and theoretical background. Starting from Van der Waals considerations on the structure of interfaces in materials the concept of the phase-field method is developed along historical...
OPENALEX
DOI: https://doi.org/10.1088/0965-0393/17/7/073001