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Expression Profiles of IGF1, EGF, and FGF2 Genes in Patients With Prostate Cancer in Isfahan Province, Iran

Farinaz Khosravian, Fatemeh Ketabchi, Nasrin Hadi, Faezeh Namazi et al. • Research in Molecular Medicine (2019)

Background: Prostate cancer is the second most prevalent cancer among men all over the world. Over the past 10 years, prostate cancer prevalence has increased in Iran. Growth factors have an important role in the regulation and growth of ma...

DOAJ Open Access (DOAJ)

Poly (ADP-ribose) Polymerase Promoter Hypermethylation Predispose Females to Breast Cancer

Hussein Sabit, Shaimaa Nazir, Shimaa Abdel-Ghany, Osama A. Said et al. • Asian Pacific Journal of Cancer Biology (2019)

Being the most common cause of female deaths worldwide, breast cancer (BC) is intensively studied over the last two decades. In the present investigation, we evaluated the promoter methylation of three cancer-related genes; PARP-1, p21, and...

DOAJ Open Access (DOAJ) DOI: 10.31557/apjcb.2019.4.1.1-5

International Journal of Medical Biotechnology & Genetics

Saket RD, Kol S, Tripathi AK, Singh SP et al. • International Journal of Medical Biotechnology & Genetics (2022)

International Journal of Medical Biotechnology & Genetics (IJMBG) ISSN: 2379-1020 is a comprehensive, peer reviewed journal devoted to Medical Biotechnology and Genetics. publishes original research, latest developments, review papers, scie...

OPENALEX cc-by DOI: https://doi.org/10.19070/2379-1020

Implications of Isoprostanes and Matrix Metalloproteinase-7 Having Potential Role in the Development of Colorectal Cancer in Males

Mahmood Rasool, Arif Malik, Ahmad Ashar Ghuman, Muhammad Abdul Basit Ashraf et al. • Frontiers in Oncology (2018)

BackgroundColorectal cancer (CRC) is the third most common type of cancer and leading cause of death worldwide. Major risk factors involved in the development of CRC are increased dietary sources, genetics, and increasing age. Purpose of th...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2018.00205

Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy

Wei Liu, Yan Xu, Yi Wang, Lugui Qiu et al. • Journal for ImmunoTherapy of Cancer (2024)

Background Over 50% of patients with relapsed or refractory large B-cell lymphoma (r/r LBCL) receiving CD19-targeted chimeric antigen receptor (CAR19) T-cell therapy fail to achieve durable remission. Early identification of relapse or prog...

DOAJ Open Access (DOAJ) DOI: 10.1136/jitc-2023-008450

Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

Xinbo Wang, Jiaying Miao, Sizhen Wang, Rongxi Shen et al. • Molecular Cancer (2022)

Abstract Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical features. Me...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-022-01596-8

A missed opportunity: faith leaders and the HPV vaccination effort in Addis Ababa, Ethiopia

Wosene Berhanu, Simon Yigremachew, Claudia Hanson, Helena Avermark et al. • Global Health Action (2026)

Background Cervical cancer causes morbidity and mortality among women worldwide, particularly in low- and middle-income countries (LMICs). Human Papillomavirus (HPV) vaccine is crucial for cervical cancer prevention, yet the vaccination rat...

DOAJ Open Access (DOAJ) DOI: 10.1080/16549716.2026.2635822

Social Media Listening to Understand the Lived Experience of Individuals in Europe With Metastatic Breast Cancer: A Systematic Search and Content Analysis Study

Manuelita Mazza, Maria Piperis, Sathyaraj Aasaithambi, Jyoti Chauhan et al. • Frontiers in Oncology (2022)

BackgroundDespite a wealth of real-world data on metastatic breast cancer (mBC), insights into the lived experience are lacking. This study aimed to explore how the lived experience of mBC is described on social media.MethodsA predefined se...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2022.863641

Formative Research on HPV Vaccine Acceptance among Health Workers, Teachers, Parents, and Social Influencers in Uzbekistan

Sahil Khan Warsi, Siff Malue Nielsen, Barbara A. K. Franklin, Shukhrat Abdullaev et al. • Vaccines (2023)

Human papillomavirus (HPV) vaccines effectively prevent cervical cancer, most of which results from undetected long-term HPV infection. HPV vaccine introduction is particularly sensitive and complicated given widespread misinformation and v...

DOAJ Open Access (DOAJ) DOI: 10.3390/vaccines11040754

Avaliação da qualidade de vida e toxicidades em pacientes com câncer colorretal tratados com quimioterapia adjuvante baseada em fluoropirimidinas Evaluation of the toxicity and quality of life in patients with colorectal cancer treated with chemotherapy

Vanessa Maria Nunes Roque, Nora Manoukian Forones • Arquivos de Gastroenterologia (2006)

RACIONAL: O câncer colorretal é a quarta causa de câncer no Brasil e o 5-fluourouracil uma das principais drogas usadas no tratamento adjuvante e paliativo dessa doença. A toxicidade da quimioterapia e as alterações de qualidade de vida, ca...

DOAJ Open Access (DOAJ) DOI: 10.1590/S0004-28032006000200007

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

Katya Carbone, Fabio Gervasi, Latipa Kozhamzharova, Nazgul Altybaeva et al. • Frontiers in Molecular Biosciences (2023)

Plants, with their range of pharmacologically active molecules, represent the most promising source for the production of new anticancer drugs and for the formulation of adjuvants in chemotherapy treatments to reduce drug content and/or cou...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmolb.2023.1157558

Cell-Based Sensors for the Detection of EGF and EGF-Stimulated Ca<sup>2+</sup> Signaling

Euiyeon Lee, Keshab Lal Shrestha, Seonhye Kang, Neethu Ramakrishnan et al. • Biosensors (2023)

Epidermal growth factor (EGF)-mediated activation of EGF receptors (EGFRs) has become an important target in drug development due to the implication of EGFR-mediated cellular signaling in cancer development. While various in vitro approache...

DOAJ Open Access (DOAJ) DOI: 10.3390/bios13030383

Lymphoid Enhancer Factor 1 Contributes to Hepatocellular Carcinoma Progression Through Transcriptional Regulation of Epithelial‐Mesenchymal Transition Regulators and Stemness Genes

Chih‐Li Chen, Yu‐Shuen Tsai, Yen‐Hua Huang, Yuh‐Jin Liang et al. • Hepatology Communications (2018)

Lymphoid enhancer factor 1 (LEF1) activity is associated with progression of several types of cancers. The role of LEF1 in progression of hepatocellular carcinoma (HCC) remains poorly known. We investigated LEF1 expression in HCC and its in...

DOAJ Open Access (DOAJ) DOI: 10.1002/hep4.1229

Associated Factors of Pre-Anesthesia Blood Pressure Elevation in Elective Non-Cardiac Surgical Patients: A Case-Control Study Comparing Two Diagnostic Thresholds

Li XM, Yang Y, Pan H, Li W et al. • Risk Management and Healthcare Policy (2026)

Xiao-Min Li,1 Yan Yang,1 Hao Pan,2 Wang Li,2 Ge-Yi Ai,2 Xi-Jiang Liu,2 Guang-Fen Zhang,2 Jie Guo31Department of Anesthesiology, Zibo Central Hospital, Zibo, People’s Republic of China; 2Department of Anesthesiology, Shandong Provincial Hosp...

DOAJ Open Access (DOAJ)

Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer

Sophia Daum, Lilith Decristoforo, Mira Mousa, Stefan Salcher et al. • Molecular Cancer (2025)

Abstract The dynamic interactions between tumor endothelial cells (TECs) and the immune microenvironment play a critical role in the progression of non-small cell lung cancer (NSCLC). In general, endothelial cells exhibit diverse immunomodu...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12943-024-02221-6

A Pilot Study to Non-Invasively Track PIK3CA Mutation in Head and Neck Cancer

Henri Schmidt, Arutha Kulasinghe, Richard J.N. Allcock, Lit Yeen Tan et al. • Diagnostics (2018)

Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs. PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway. PIK3CA has been impl...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics8040079

Sociodemographic Factors and Depression in Patients With Breast Cancer: A Multicenter, Cross-sectional Study in Georgia

Tamar Kakhniashvili, Nino Okribelashvili, Ivane Kiladze • Breast Cancer: Basic and Clinical Research (2025)

Background: Depression commonly occurs in patients with breast cancer (BC), affecting their quality of life. Objectives: The relationships between depression and different sociodemographic characteristics in patients with BC are under-resea...

DOAJ Open Access (DOAJ) DOI: 10.1177/11782234251323775

A Predictive Model Based on the Gut Microbiota Improves the Diagnostic Effect in Patients With Cholangiocarcinoma

Tan Zhang, Tan Zhang, Sina Zhang, Sina Zhang et al. • Frontiers in Cellular and Infection Microbiology (2021)

Cholangiocarcinoma (CCA) is a malignant hepatic tumor with a poor prognosis, which needs early diagnosis urgently. The gut microbiota has been shown to play a crucial role in the progression of liver cancer. Here, we explored a gut microbio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2021.751795