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Association of androgen receptor and tumour-infiltrating lymphocytes with bone recurrence in triple-negative breast cancer

Petra Ilenič, Ajda Herman, Erik Langerholc, Barbara Gazić et al. • Journal of Bone Oncology (2024)

Background: As compared to endocrine responsive breast cancer bone is less frequent site of distant recurrence in triple-negative breast cancer (TNBC). A biomarker which predicts bone recurrence would allow a more personalized treatment app...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jbo.2023.100518

Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial

Monika Ludlova, Kateřina Koudelková, Jitka Pallova, Barbora Koudelkova et al. • JMIR Research Protocols (2025)

BackgroundWeight loss is a cornerstone of obesity treatment and diabetes mellitus type 2 (T2D) prevention, but its implementation in clinical practice is limited by its perceived burden and variability in response. Personalizing interventio...

DOAJ Open Access (DOAJ) DOI: 10.2196/67570

Structural dataset for the PPARγ V290M mutant

Ana C. Puhl, Paul Webb, Igor Polikarpov • Data in Brief (2016)

Loss-of-function mutation V290M in the ligand-binding domain of the peroxisome proliferator activated receptor γ (PPARγ) is associated with a ligand resistance syndrome (PLRS), characterized by partial lipodystrophy and severe insulin resis...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2016.03.082

Identifying Applied Aspects, Medical Fields, and Technological Trends in Developing Future Entrepreneurial Opportunities in Telemedicine

Ali Mobini-Dehkordi, Jahangir Yadolai-Farsi, Abolghasem Arabiun, Mustafa Keshavarz-Turk • مدیریت اطلاعات سلامت (2021)

Introduction: Parallel with the growth of technologies, which affect the telemedicine, timely identification of telemedicine entrepreneurial opportunities seems to be necessary for the product development. This study aimed to identify appli...

DOAJ Open Access (DOAJ) DOI: 10.22122/him.v17i6.4230

Effectiveness and Related Factors of Narrative Messages in Correcting Health-Related Misinformation: Protocol for a Systematic Review

Tsuyoshi Okuhara, Hiroko Okada, Rie Yokota • JMIR Research Protocols (2025)

BackgroundThe internet and social media have become essential sources of health information for patients and citizens; however, they often disseminate misinformation that lacks scientific evidence. Health-related misinformation can undermin...

DOAJ Open Access (DOAJ) DOI: 10.2196/69414

Development and validation of an interpretable machine learning model for predicting the risk of coronary heart disease risk in diabetes mellitus patients: a dual-center retrospective study

Ye Kuang, Yan Yu, Jing Li, Chuanmei Peng et al. • BMC Medical Informatics and Decision Making (2026)

Abstract Background Diabetes mellitus (DM) combined with coronary heart disease (CHD) significantly increases the risk of cardiovascular events with a greater mortality rate. Therefore, establishing a predictive model can help DM patients r...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12911-026-03461-w

Behind the scars: adolescents with non-suicidal self-injury disorder show profound personality pathology

Manuela Gander, Kirstin Goth, Josef Fritz, Kathrin Sevecke • Child and Adolescent Psychiatry and Mental Health (2026)

Abstract Background Non-suicidal self-injury is a significant clinical concern in adolescent psychiatry and frequently co-occurs with a range of psychiatric disorders, including mood disorders, eating disorders, substance use disorders, and...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13034-026-01075-8

Oxygen nanobubbles of ICG dimers achieve self-cascade photothermal and photodynamic therapy for hypoxia-reversible tumor treatment

Xiang Sun, Zheng Zhang, Moran Wang, Yuqin Chen et al. • Nano Research (2025)

Simultaneous photothermal and photodynamic therapies (PTT and PDT) hold great promise for noninvasive tumor therapy. However, effective regulation of PTT and PDT with optimal synergistic effects remains a challenge. To date, there are only ...

DOAJ Open Access (DOAJ) DOI: 10.26599/NR.2025.94907281

The deep learning applications in IoT-based bio- and medical informatics: a systematic literature review

Zahra Amiri, Arash Heidari, Nima Jafari Navimipour, Mansour Esmaeilpour et al. • Neural Computing and Applications (2024)

Abstract Nowadays, machine learning (ML) has attained a high level of achievement in many contexts. Considering the significance of ML in medical and bioinformatics owing to its accuracy, many investigators discussed multiple solutions for ...

OPENALEX cc-by DOI: https://doi.org/10.1007/s00521-023-09366-3

From Connectivity to Controllability: Unraveling the Brain Biomarkers of Major Depressive Disorder

Chunyu Pan, Ying Ma, Lifei Wang, Yan Zhang et al. • Brain Sciences (2024)

Major Depressive Disorder (MDD) is a significant neurological condition associated with aberrations in brain functional networks. Traditional studies have predominantly analyzed these from a network topology perspective. However, given the ...

DOAJ Open Access (DOAJ) DOI: 10.3390/brainsci14050509

Is telemedicine a subset of medical informatics?

Shyamala Nagendran, David Moores, Rick Spooner, Jean A. C. Triscott • Journal of Telemedicine and Telecare (2000)

Informatics has a key characteristic of a new discipline in a technically transient environment--there is no universal definition of it. This is not surprising, given its complex and diverse nature. In a broad sense informatics is the inter...

OPENALEX DOI: https://doi.org/10.1258/1357633001935563

Modulation of frontal gamma oscillations improves working memory in schizophrenia

Fiza Singh, I-Wei Shu, Sheng-Hsiou Hsu, Peter Link et al. • NeuroImage: Clinical (2020)

Schizophrenia is a debilitating mental disorder that is associated with cognitive deficits. Impairments in cognition occur early in the course of illness and are associated with poor functional outcome, but have been difficult to treat with...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2020.102339

Lessons From a Rapid Project Management Exercise in the Time of Pandemic: Methodology for a Global COVID-19 VIRUS Registry Database

Janice R Turek, Vikas Bansal, Aysun Tekin, Shuchita Singh et al. • JMIR Research Protocols (2022)

BackgroundThe rapid emergence of the COVID-19 pandemic globally collapsed health care organizations worldwide. Incomplete knowledge of best practices, progression of disease, and its impact could result in fallible care. Data on symptoms an...

DOAJ Open Access (DOAJ) DOI: 10.2196/27921

Data on the cytotoxicity of chlorogenic acid in 3D cultures of HT-29 cells

M. Daniela Vélez, Johanna Pedroza-Díaz, Gloria A. Santa-González • Data in Brief (2023)

Functional foods, beyond basic nutrition, offer health benefits to consumers thanks to the presence of bioactive compounds such as some phytochemicals [1,2]. Today, these foods are of particular interest in biomedical research due to their ...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.dib.2023.109527

Lifestyle Change Interventions for Children and Adolescents With Diabetes or Kidney Disease

Lori L. Sanderson MSW, MPH • Journal of Primary Care & Community Health (2010)

The purpose of this research letter is to report on the availability of evidence-based interventions for promoting lifestyle change in children and adolescents with diabetes or kidney disease. References for this review were obtained using ...

DOAJ Open Access (DOAJ) DOI: 10.1177/2150131909358185

A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

Michael Barnett, Dongang Wang, Heidi Beadnall, Antje Bischof et al. • npj Digital Medicine (2023)

Abstract Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical relapses, no magnetic resonance imaging (MRI) disease activity and no disability worsening. While MRI is the principal tool available to neurologis...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41746-023-00940-6

Denosumab and Bisphosphonate Treatment of Osteoporosis in Renal Transplant Recipients

Serdar Şahin, Nurhan Seyahi, Sinan Trabulus, Hande Mefkure Özkaya et al. • Cerrahpaşa Medical Journal (2021)

Objective: Kidney transplant recipients are at risk of losing bone mineral density. Osteoporosis and fractures cause serious complications in renal transplant recipients. We aimed to evaluate the efficacy and safety of bisphosphonate and de...

DOAJ Open Access (DOAJ) DOI: 10.5152/cjm.2021.21039

Combining Digital Cognitive Behavioral Therapy With Mindfulness Training for Binge Eating Disorder: Protocol for a Feasibility Trial

Margaret Sala, Corey Roos, Dante Ascarrunz, Casey M Stern et al. • JMIR Research Protocols (2026)

BackgroundCognitive behavioral therapy (CBT) is the most effective treatment for binge eating disorder (BED) but is limited by modest efficacy and low reach of in-person delivery. Combining mindfulness training with CBT could enhance effica...

DOAJ Open Access (DOAJ) DOI: 10.2196/91761

Percutaneous CT-Guided Bone Lesion Biopsy for Confirmation of Bone Metastases in Patients with Breast Cancer

Lucija Kovacevic, Mislav Cavka, Zlatko Marusic, Elvira Kresic et al. • Diagnostics (2022)

We aimed to determine diagnostic accuracy of CT-guided bone lesion biopsy for the confirmation of bone metastases in patients with breast cancer and assessment of hormone receptor status in metastatic tissue. A total of 56 female patients w...

DOAJ Open Access (DOAJ) DOI: 10.3390/diagnostics12092094