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Showing 20 of 742 academic articles

Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors

Safwaan H. Khan, Safwaan H. Khan, Yeonjoo Choi, Mysore Veena et al. • Frontiers in Immunology (2025)

Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of hematologic malignancies, achieving remarkable clinical success with FDA-approved therapies targeting CD19 and BCMA. However, the extension of these successe...

DOAJ Open Access (DOAJ) DOI: 10.3389/fimmu.2024.1489827

Worldwide productivity and research trend of publications concerning extracellular vesicles role in fibrosis: A bibliometric study from 2013 to 2022

Ya-Wen Peng, Ri Tang, Qiao-Yi Xu, Shu-Ya Mei et al. • Heliyon (2024)

Background: Fibrosis is a heavy burden on the global healthcare system. Recently, an increasing number of studies have demonstrated that Extracellular vesicles play an important role in intercellular communication under both physiological a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2024.e24357

Modelling the trends of the healthcare funding in the EU countries

Nadiya Dubrovina, Russell Gerrard, Stanislav Filip, Vira Dubrovina • Przegląd Europejski (2021)

Healthcare is one of the most important sectors of the public economy in the EU countries. An important task in the analysis and prediction of the values for healthcare funding is the development and application of quantitative models based...

DOAJ Open Access (DOAJ) DOI: 10.31338/1641-2478pe.1.21.4

A qualitative study of developing beliefs about health, illness and healthcare in migrant African women with gestational diabetes living in Sweden

Katarina Hjelm, Karin Bard, Jan Apelqvist • BMC Women's Health (2018)

Abstract Background Gestational diabetes (GDM) is associated with health risks for both mother and child, and is particularly relevant to migrant women and women of African origin. With today’s extensive global migration, contact with the n...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12905-018-0518-z

Incidence of suicidality in people with depression over a 10-year period treated by a large UK mental health service provider

Emma R. Francis, Daniela Fonseca de Freitas, Craig Colling, Megan Pritchard et al. • BJPsych Open (2021)

We describe the incidence of suicidality (2007–2017) in people with depression treated by secondary mental healthcare services at South London and Maudsley NHS Trust (n = 26 412). We estimated yearly incidence of ‘suicidal ideation’ and ‘hi...

DOAJ Open Access (DOAJ) DOI: 10.1192/bjo.2021.1054

Variation in TMEM106B in chronic traumatic encephalopathy

Jonathan D. Cherry, Jesse Mez, John F. Crary, Yorghos Tripodis et al. • Acta Neuropathologica Communications (2018)

Abstract The genetic basis of chronic traumatic encephalopathy (CTE) is poorly understood. Variation in transmembrane protein 106B (TMEM106B) has been associated with enhanced neuroinflammation during aging and with TDP-43-related neurodege...

DOAJ Open Access (DOAJ) DOI: 10.1186/s40478-018-0619-9

Piezo1 knockdown activates PI3K/AKT and enhances SPP1 to drive M2 macrophage polarization and reduce cardiac inflammation

Yunhan Zhang, Ying Zhang, Jiaoyan Song, Ziwen Zhao et al. • Scientific Reports (2026)

Abstract Piezo1 plays a key role in the immune response during sepsis. To date, our understanding of the role of Piezo1 in inflammatory diseases has mostly been limited to influencing vasomotor function and regulating inflammatory infiltrat...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-34794-7

Exploring innovation landscapes: a national cross-sectional study of Swedish primary care from the viewpoint of primary care managers

Sarah Samuelson, Eva-Lisa Petersson, Cecilia Björkelund, Marcus Praetorius Björk et al. • BMC Health Services Research (2026)

Abstract Background Innovation is increasingly necessary in primary care policy, and healthcare managers play a pivotal role in translating policy ambitions into practice and shaping organisational conditions that foster innovation. The aim...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-026-14870-y

Analysing interventions designed to reduce tuberculosis-related stigma: A scoping review.

Isabel Foster, Michelle Galloway, Wieda Human, Michaile Anthony et al. • PLOS Global Public Health (2022)

Stigma is a critical barrier for TB care delivery; yet data on stigma reduction interventions is limited. This review maps the available literature on TB stigma reduction interventions, using the Health Stigma and Discrimination framework a...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pgph.0000989

Views of generation Z nurse candidates on their willingness to work in featured services in hospitals: A qualitative study

Yasin Cetin, Asli Tok Ozen, Mumin Savas • Medicine Science (2024)

The aim of this study is to identify the willingness of generation Z nursing students to work in the specialized units, as well as their views about these units, and to find answers to issues such as which units they want to work in and why...

DOAJ Open Access (DOAJ) DOI: 10.5455/medscience.2023.08.154

Understanding patient perspectives on digital therapeutics and its platform for insomnia: insights from focused group interviews

Jinhyun Kim, Kyung Mee Park, Suonaa Lee, Sooji Park et al. • BMC Health Services Research (2024)

Abstract Background Digital therapeutics (DTx) is a treatment option that uses computer software to provide evidence-based interventions for medical disorders. DTx platforms are digital services that facilitate interactions among stakeholde...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12913-024-11286-4

Quantifying Gender Bias in Large Language Models Using Information-Theoretic and Statistical Analysis

Imran Mirza, Akbar Anbar Jafari, Cagri Ozcinar, Gholamreza Anbarjafari • Information (2025)

Large language models (LLMs) have revolutionized natural language processing across diverse domains, yet they also raise critical fairness and ethical concerns, particularly regarding gender bias. In this study, we conduct a systematic, mat...

DOAJ Open Access (DOAJ) DOI: 10.3390/info16050358

AI-generated draft replies to patient messages: exploring effects of implementation

Charlotte M. H. H. T. Bootsma-Robroeks, Charlotte M. H. H. T. Bootsma-Robroeks, Jessica D. Workum, Jessica D. Workum et al. • Frontiers in Digital Health (2025)

IntroductionThe integration of Large Language Models (LLMs) in Electronic Health Records (EHRs) has the potential to reduce administrative burden. Validating these tools in real-world clinical settings is essential for responsible implement...

DOAJ Open Access (DOAJ) DOI: 10.3389/fdgth.2025.1588143

A systematic review of natural language processing applied to radiology reports

Arlene Casey, Emma Davidson, Michael Poon, Hang Dong et al. • BMC Medical Informatics and Decision Making (2021)

BACKGROUND: Natural language processing (NLP) has a significant role in advancing healthcare and has been found to be key in extracting structured information from radiology reports. Understanding recent developments in NLP application to r...

OPENALEX cc-by DOI: https://doi.org/10.1186/s12911-021-01533-7 PMC: 8176715

NATURAL LANGUAGE PROCESSING IN HEALTHCARE

Matthew N. O. Sadiku, Yu Zhou, Sarhan M. Musa • International Journal of Advanced Research in Computer Science and Software Engineering (2018)

Natural language processing (NLP) refers to the process of using of computer algorithms to identify key elements in everyday language and extract meaning from unstructured spoken or written communication. Healthcare is the biggest user of t...

OPENALEX DOI: https://doi.org/10.23956/ijarcsse.v8i5.626

Mapping inequities in global vaccine sentiment research

Aleksandra Torbica, Deepak Sharma, Duilio Balsamo, Vittoria Offeddu et al. • BMJ Global Health (2025)

Introduction Negative public sentiment towards vaccination (PSV) poses significant challenges to the effectiveness of immunisation programmes, with dramatic effects on morbidity and mortality for vaccine-preventable diseases. Yet, health re...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjgh-2024-018587

Natural language processing applied to mental illness detection: a narrative review

Tianlin Zhang, Annika Marie Schoene, Shaoxiong Ji, Sophia Ananiadou • npj Digital Medicine (2022)

Mental illness is highly prevalent nowadays, constituting a major cause of distress in people's life with impact on society's health and well-being. Mental illness is a complex multi-factorial disease associated with individual risk factors...

OPENALEX cc-by DOI: https://doi.org/10.1038/s41746-022-00589-7 PMC: 8993841

Evaluation of the accuracy of ChatGPT-4 and Gemini’s responses to the World Dental Federation’s frequently asked questions on oral health

Aysenur Arpaci, Asel Usdat Ozturk, Ismail Okur, Sanaz Sadry • BMC Oral Health (2025)

Abstract Background The field of artificial intelligence (AI) has experienced considerable growth in recent years, with the advent of technologies that are transforming a range of industries, including healthcare and dentistry. Large langua...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12903-025-06624-9