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Showing 20 of 992 academic articles

Demonstration of high value care to improve oral health of a remote Indigenous community in Australia

Sanjeewa Kularatna, Ratilal Lalloo, Jeroen Kroon, Santosh K. K. Tadakamadla et al. • Health and Quality of Life Outcomes (2020)

Abstract Background The oral health of Indigenous children in remote communities is much worse than other population groups in Australia. Providing and maintaining an oral health service is challenging due to the remoteness of communities, ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12955-020-01300-8

Association between social health status and health-related quality of life among community-dwelling elderly in Zhejiang

Jieming Lu, Zhebin Yu, Xiaocong Zhang, Mengyin Wu et al. • Health and Quality of Life Outcomes (2020)

Abstract Background Population aging is an inevitable trend and previous studies have showed the relationship between social health related factors and health-related quality of life (HR-QOL) in the elderly. The objective of this study is t...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12955-020-01358-4

Web-based versus simulation-based refresher training in newborn life support

Kathleen Parthey, Anne Goldhahn, Anselm Linke, Katja Raberger et al. • Resuscitation Plus (2026)

Background: Regular training for healthcare professionals in newborn life support is life-saving. Web-based refresher has the potential to be non-inferior to simulation-based refresher training. Methods: The multicenter non-inferiority rand...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.resplu.2026.101382

Comparative assessment of patient education content generated by five large language models on post-stroke complications: A cross-sectional study of safety, accuracy, reliability, readability, and empathy

Long-Xian Liu, Huan-Huan Wang, Shuang Lu, Guo Yu et al. • Digital Health (2026)

Objective To compare the safety, accuracy, reliability, readability, and empathy of patient education content generated by five large language models (LLMs) for post-stroke complications. Methods This CHART-guided cross-sectional comparativ...

DOAJ Open Access (DOAJ) DOI: 10.1177/20552076261493266

Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity

Maaike C. Swets, Steven Kerr, James Scott-Brown, Adam B. Brown et al. • Nature Communications (2023)

Abstract Choosing optimal outcome measures maximizes statistical power, accelerates discovery and improves reliability in early-phase trials. We devised and evaluated a modification to a pragmatic measure of oxygenation function, the $$S/F$...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-023-42205-6

‘Optimal’ cutoff selection in studies of depression screening tool accuracy using the PHQ‐9, EPDS, or HADS‐D: A meta‐research study

Eliana Brehaut, Dipika Neupane, Brooke Levis, Yin Wu et al. • International Journal of Methods in Psychiatric Research (2023)

Abstract Objectives Optimal cutoff thresholds are selected to separate ‘positive’ from ‘negative’ screening results. We evaluated how depression screening tool studies select optimal cutoffs. Methods We included studies from previously cond...

DOAJ Open Access (DOAJ) DOI: 10.1002/mpr.1956

Fast Healthcare Interoperability Resources (FHIR) for Interoperability in Health Research: Systematic Review

Carina Nina Vorisek, Moritz Lehne, Sophie Anne Ines Klopfenstein, Paula Josephine Mayer et al. • JMIR Medical Informatics (2022)

BackgroundThe standard Fast Healthcare Interoperability Resources (FHIR) is widely used in health information technology. However, its use as a standard for health research is still less prevalent. To use existing data sources more efficien...

DOAJ Open Access (DOAJ) DOI: 10.2196/35724

Automated measurement of CD8+ T-cell distribution at the tumor epithelial–stromal interface is associated with NSCLC immunotherapy benefit and transcriptomic pathways

Patrick Leo, Hauke Kolster, Hartmut Koeppen, Jennifer Giltnane et al. • Journal of Pathology Informatics (2026)

Whereas anti-PD-(L)1 therapies are widely used in cancer treatment, only a subset of patients achieve long-term survival. Companion diagnostics based on PD-L1 expression have limited predictive power for these therapies, motivating developm...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jpi.2026.100688

The effect of structured medication review followed by face-to-face feedback to prescribers on adverse drug events recognition and prevention in older inpatients – a multicenter interrupted time series study

Joanna E. Klopotowska, Paul F. M. Kuks, Peter C. Wierenga, Clementine C. M. Stuijt et al. • BMC Geriatrics (2022)

Abstract Background The effectiveness of interventions to improve medication safety in older inpatients is unclear, given a paucity of properly designed intervention studies applying clinically relevant endpoints such as hospital-acquired p...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-022-03118-z

Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial

Monika Ludlova, Kateřina Koudelková, Jitka Pallova, Barbora Koudelkova et al. • JMIR Research Protocols (2025)

BackgroundWeight loss is a cornerstone of obesity treatment and diabetes mellitus type 2 (T2D) prevention, but its implementation in clinical practice is limited by its perceived burden and variability in response. Personalizing interventio...

DOAJ Open Access (DOAJ) DOI: 10.2196/67570

Cross-cultural adaptation and psychometric properties of the Kessler Scale of Psychological Distress to a traumatic brain injury population in Swahili and the Tanzanian Setting

Joao Ricardo Nickenig Vissoci, Silvia Daniela Vaca, Deena El-Gabri, Leonardo Pestillo de Oliveira et al. • Health and Quality of Life Outcomes (2018)

Abstract Background To evaluate the psychometric properties of a Swahili version of the Kessler Psychological Distress scale in an injury population in Tanzania. Methods Swahili version of the Kessler Psychological Distress scale was develo...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12955-018-0973-0

Remote Patient Monitoring System for Polypathological Older Adults at High Risk for Hospitalization: Retrospective Cohort Study

Damien Testa, Israa Salma, Vincent Iborra, Victoire Roussel et al. • Journal of Medical Internet Research (2025)

Abstract BackgroundHealth care systems are increasingly facing challenges posed by the aging of populations. In particular, hospitalization, both initial and subsequent, is often observed among older adult patients. However, res...

DOAJ Open Access (DOAJ) DOI: 10.2196/71527

Effectiveness and Related Factors of Narrative Messages in Correcting Health-Related Misinformation: Protocol for a Systematic Review

Tsuyoshi Okuhara, Hiroko Okada, Rie Yokota • JMIR Research Protocols (2025)

BackgroundThe internet and social media have become essential sources of health information for patients and citizens; however, they often disseminate misinformation that lacks scientific evidence. Health-related misinformation can undermin...

DOAJ Open Access (DOAJ) DOI: 10.2196/69414

Implementing and Evaluating a National Integrated Digital Registry and Clinical Decision Support System in Early Intervention in Psychosis Services (Early Psychosis Informatics Into Care): Co-Designed Protocol

Siân Lowri Griffiths, Graham K Murray, Yanakan Logeswaran, John Ainsworth et al. • JMIR Research Protocols (2024)

BackgroundEarly intervention in psychosis (EIP) services are nationally mandated in England to provide multidisciplinary care to people experiencing first-episode psychosis, which disproportionately affects deprived and ethnic minority yout...

DOAJ Open Access (DOAJ) DOI: 10.2196/50177

An Integrated Approach for Designing and Analyzing Lumbar Vertebral Biomodels with Artificial Disc Replacement

Mhd Ayham Darwich, Katreen Ebrahem, Maysaa Shash, Hasan Mhd Nazha et al. • Applied Mechanics (2023)

This study aims to develop an integrated approach for 3D lumbar vertebral biomodel design and analysis, specifically targeting unilevel disc degeneration and the replacement of lumbar artificial discs. Key objectives include improving exist...

DOAJ Open Access (DOAJ) DOI: 10.3390/applmech4040063

The deep learning applications in IoT-based bio- and medical informatics: a systematic literature review

Zahra Amiri, Arash Heidari, Nima Jafari Navimipour, Mansour Esmaeilpour et al. • Neural Computing and Applications (2024)

Abstract Nowadays, machine learning (ML) has attained a high level of achievement in many contexts. Considering the significance of ML in medical and bioinformatics owing to its accuracy, many investigators discussed multiple solutions for ...

OPENALEX cc-by DOI: https://doi.org/10.1007/s00521-023-09366-3

Impact of a Mobile App (LoAD Calc) on the Calculation of Maximum Safe Doses of Local Anesthetics: Protocol for a Randomized Controlled Trial

Pietro Elias Fubini, Georges Louis Savoldelli, Tal Sara Beckmann, Caroline Flora Samer et al. • JMIR Research Protocols (2024)

BackgroundLocal anesthetics (LAs) are regularly used to alleviate pain during medical or surgical procedures. Their use is generally considered safe, but exceeding the maximum recommended doses can lead to LA systemic toxicity, a rare but p...

DOAJ Open Access (DOAJ) DOI: 10.2196/53679

Modulation of frontal gamma oscillations improves working memory in schizophrenia

Fiza Singh, I-Wei Shu, Sheng-Hsiou Hsu, Peter Link et al. • NeuroImage: Clinical (2020)

Schizophrenia is a debilitating mental disorder that is associated with cognitive deficits. Impairments in cognition occur early in the course of illness and are associated with poor functional outcome, but have been difficult to treat with...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2020.102339