Academic Articles & Research Papers

Brain perfusion imaging in neonates

Abnormal variations of the neonatal brain perfusion can result in long-term neurodevelopmental consequences and cerebral perfusion imaging can play an important role in diagnostic and therapeutic decision-making. To identify at-risk situati...

Modulation of frontal gamma oscillations improves working memory in schizophrenia

Schizophrenia is a debilitating mental disorder that is associated with cognitive deficits. Impairments in cognition occur early in the course of illness and are associated with poor functional outcome, but have been difficult to treat with...

Structural relationships within medical informatics

Medical informatics is the application of information science and information technology to the theoretical and practical problems of biomedical research, clinical practice, and medical education. Although it is broadly interdisciplinary, i...

eHealth for Addressing Balance Disorders in the Elderly: Systematic Review

BackgroundThe population is aging on a global scale, triggering vulnerability for chronic multimorbidity, balance disorders, and falls. Falls with injuries are the main cause of accidental death in the elderly population, representing a rel...

“I think it's something that we should lean in to”: The use of OpenNotes in Canadian psychiatric care contexts by clinicians

Background OpenNotes is the concept of patients having access to their health records and clinical notes in a digital form. In psychiatric settings, clinicians often feel uncomfortable with this concept, and require support during implement...

A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis

Abstract Modern management of MS targets No Evidence of Disease Activity (NEDA): no clinical relapses, no magnetic resonance imaging (MRI) disease activity and no disability worsening. While MRI is the principal tool available to neurologis...

A Focus on Simulation in Medical Informatics

This special issue of JAMIA addresses simulation, a methodology that holds great promise for the advancement of information technology in health care. Simulation has been termed a third domain, complementing both natural language and mathem...

Effects of individualized rTMS on functional connectivity related to the default mode network and frontal-parietal network in major depressive disorder: exploratory analysis of a randomized controlled trial

Objective: Repetitive transcranial magnetic stimulation (rTMS) has been shown to alleviate depressive and anxiety symptoms in patients with major depressive disorder (MDD), typically by targeting the dorsolateral (DLPFC) or dorsomedial pref...

Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial

The specificity and implementation of current MRI-based diagnostic criteria for multiple sclerosis (MS) are imperfect. Approximately 1 in 5 of individuals diagnosed with MS are eventually determined not to have the disease, with overrelianc...

Health-related quality of life in Chinese population with non-alcoholic fatty liver disease: a national multicenter survey

Abstract Background Health Related Quality of Life (HRQL) is a multi-dimensional construct that can comprehensively evaluate the patient’s health status, including physical, emotional, mental and social well-being. In this study, we aimed t...

Psychogeriatrics and Medical Informatics

The rapid growth of the field of psychogeriatrics, spurred on by aging populations, substantially increased funding, and growing interest by professionals, government, and society, has led, in turn, to a rapid growth of medical information....

UPDATED GUIDELINE FOR VALIDATING WHOLE SLIDE IMAGING SYSTEMS FROM THE COLLEGE OF AMERICAN PATHOLOGISTS

On the correspondence between the transcriptomic response of a compound and its effects on its targets

Abstract Better understanding the transcriptomic response produced by a compound perturbing its targets can shed light on the underlying biological processes regulated by the compound. However, establishing the relationship between the indu...

Challenges in Medical Informatics: Perspectives of an International Medical Informatics Organization

OBJECTIVE: As an international organization with the missions to promote informatics in health care and biomedical research, advance international cooperation, stimulate research, development and education, and disseminate and exchange info...

Grey matter volume associations with personality functioning in a clinical cohort of female youths

Borderline Personality Disorder (BPD) is a severe mental illness, although its neurobiological underpinnings remain largely unknown. Structural Magnetic Resonance Imaging (sMRI) in adolescents can offer insights into potential biomarkers to...

Correction: Five-year dementia prediction and decision support system based on real-world data

Antecedents of the People and Organizational Aspects of Medical Informatics: Review of the Literature

People and organizational issues are critical in both implementing medical informatics systems and in dealing with the altered organizations that new systems often create. The people and organizational issues area--like medical informatics ...

Bioinformatics and Medical Informatics: Collaborations on the Road to Genomic Medicine?

In this report, the authors compare and contrast medical informatics (MI) and bioinformatics (BI) and provide a viewpoint on their complementarities and potential for collaboration in various subfields. The authors compare MI and BI along s...

e-Health interventions for healthy aging: a systematic review

Abstract Background Healthy aging (HA) is a contemporary challenge for population health worldwide. Electronic health (e-Health) interventions have the potential to support empowerment and education of adults aged 50 and over. Objectives To...

Data for: Terrain units, land use/cover, and gross primary productivity of the largest fluvial basin in the Brazilian Amazonia/Cerrado ecotone: The Araguaia River Basin

Integrity of most of tropical wetlands is threatened because they are often considered freely available resources of land and water. The Araguaia River Basin is one of the Brazilian basins most influenced by tropical seasonal floods, in add...