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Showing 9 of 49 academic articles

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

Linda Nötzold, Lukas Frank, Minakshi Gandhi, Maria Polycarpou-Schwarz et al. • Scientific Reports (2017)

Abstract In recent years, long non-coding RNA (lncRNA) research has identified essential roles of these transcripts in virtually all physiological cellular processes including tumorigenesis, but their functions and molecular mechanisms are ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-017-02357-0

Identification of immune-associated biomarkers of diabetes nephropathy tubulointerstitial injury based on machine learning: a bioinformatics multi-chip integrated analysis

Lin Wang, Jiaming Su, Zhongjie Liu, Shaowei Ding et al. • BioData Mining (2024)

Abstract Background Diabetic nephropathy (DN) is a major microvascular complication of diabetes and has become the leading cause of end-stage renal disease worldwide. A considerable number of DN patients have experienced irreversible end-st...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13040-024-00369-x

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

Meiyu Shao, Xiaoqing Zhang, Jiamei Sun, Hongyan Dong et al. • Exploration (2025)

ABSTRACT Saikosaponin b1 (Ssb1), a natural oleanane‐type triterpenoid saponin, exhibits antifibrosis activity by inhibiting the activation of hepatic stellate cells (HSCs), but the specific underlying molecular mechanisms are unknown. Here,...

DOAJ Open Access (DOAJ) DOI: 10.1002/EXP.70000

MP-VHPPI: Meta predictor for viral host protein-protein interaction prediction in multiple hosts and viruses

Muhammad Nabeel Asim, Muhammad Nabeel Asim, Ahtisham Fazeel, Ahtisham Fazeel et al. • Frontiers in Medicine (2022)

Viral-host protein-protein interaction (VHPPI) prediction is essential to decoding molecular mechanisms of viral pathogens and host immunity processes that eventually help to control the propagation of viral diseases and to design optimized...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.1025887