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Neurological Manifestations of SARS-CoV-2 Infection: Protocol for a Sub-analysis of the COVID-19 Critical Care Consortium Observational Study

Denise Battaglini, Denise Battaglini, Lavienraj Premraj, Lavienraj Premraj et al. • Frontiers in Medicine (2022)

IntroductionNeurological manifestations and complications in coronavirus disease-2019 (COVID-19) patients are frequent. Prior studies suggested a possible association between neurological complications and fatal outcome, as well as the exis...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2022.930217

Inspiratory pressure waveform influences time to failure, respiratory muscle fatigue, and metabolism during resistive breathing

Mathias Krogh Poulsen, Stephen E. Rees, John Hansen, Andrew J. T. Stevenson et al. • Physiological Reports (2023)

Abstract Increased ventilatory work beyond working capacity of the respiratory muscles can induce fatigue, resulting in limited respiratory muscle endurance (Tlim). Previous resistive breathing investigations all applied square wave inspira...

DOAJ Open Access (DOAJ) DOI: 10.14814/phy2.15668

Web-based versus simulation-based refresher training in newborn life support

Kathleen Parthey, Anne Goldhahn, Anselm Linke, Katja Raberger et al. • Resuscitation Plus (2026)

Background: Regular training for healthcare professionals in newborn life support is life-saving. Web-based refresher has the potential to be non-inferior to simulation-based refresher training. Methods: The multicenter non-inferiority rand...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.resplu.2026.101382

Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity

Maaike C. Swets, Steven Kerr, James Scott-Brown, Adam B. Brown et al. • Nature Communications (2023)

Abstract Choosing optimal outcome measures maximizes statistical power, accelerates discovery and improves reliability in early-phase trials. We devised and evaluated a modification to a pragmatic measure of oxygenation function, the $$S/F$...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-023-42205-6

Brain perfusion imaging in neonates

Jérôme Baranger, Olivier Villemain, Matthias Wagner, Mariella Vargas-Gutierrez et al. • NeuroImage: Clinical (2021)

Abnormal variations of the neonatal brain perfusion can result in long-term neurodevelopmental consequences and cerebral perfusion imaging can play an important role in diagnostic and therapeutic decision-making. To identify at-risk situati...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nicl.2021.102756

The influence of patient characteristics on the alarm rate in intensive care units: a retrospective cohort study

Zeena-Carola Sinno, Denys Shay, Jochen Kruppa, Sophie A.I. Klopfenstein et al. • Scientific Reports (2022)

Abstract Intensive care units (ICU) are often overflooded with alarms from monitoring devices which constitutes a hazard to both staff and patients. To date, the suggested solutions to excessive monitoring alarms have remained on a research...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-022-26261-4

The relationship between informatics competency and clinical competency in nurses working in intensive care units: A Cross-sectional Study in Northeast Iran

Fatemeh Tahmasbi, Khadijeh Yazdi, Navisa Sadat Seyedghasemi, Shohreh Kolagari • Journal of Research Development in Nursing and Midwifery (2024)

Background: The use of information technology improves the competency of nurses at the bedside. This study was conducted to determine the relationship between informatics competency and clinical competency in nurses working in intensive car...

DOAJ Open Access (DOAJ)

Mortality trends among hospitalised COVID-19 patients in Sweden: A nationwide observational cohort study

Kristoffer Strålin, Erik Wahlström, Sten Walther, Anna M Bennet-Bark et al. • The Lancet Regional Health. Europe (2021)

Background: It is important to know if mortality among hospitalised COVID-19 patients has changed as the pandemic has progressed. The aim of this study was to describe the dynamics over time of mortality among patients hospitalised for COVI...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.lanepe.2021.100054

Why do healthcare professionals fail to escalate as per the early warning system (EWS) protocol? A qualitative evidence synthesis of the barriers and facilitators of escalation

S. M. O’Neill, B. Clyne, M. Bell, A. Casey et al. • BMC Emergency Medicine (2021)

Abstract Background Early warning systems (EWSs) are used to assist clinical judgment in the detection of acute deterioration to avoid or reduce adverse events including unanticipated cardiopulmonary arrest, admission to the intensive care ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12873-021-00403-9

Chimeric antigen receptor T‐cell therapy: Challenges and framework of outpatient administration

Katie S. Gatwood, Bhagirathbhai R. Dholaria, Mariana Lucena, Brittney Baer et al. • eJHaem (2022)

Abstract Adoptive cellular therapy has made a landmark change within the treatment paradigm of several hematologic malignancies, and novel cellular therapy products, such as chimeric antigen receptor T‐cell therapy (CART), have demonstrated...

DOAJ Open Access (DOAJ) DOI: 10.1002/jha2.333

Epidemiology of Drowning Incidents among Children at Sultan Qaboos University Hospital Oman

Niranjan Lal Jeswani, Muhammad Faisal Khilji, Syed Rizvi, Abdullah Al Reesi • Oman Medical Journal (2021)

Objectives: We sought to study the epidemiology of drowning among children reported at Sultan Qaboos University Hospital in Oman. Methods: We conducted a retrospective study of the patients who presented to the emergency department with a h...

DOAJ Open Access (DOAJ) DOI: 10.5001/omj.2021.104

The Utilization of Point of Care Ultrasound (POCUS) for the Confirmation of Gastric and Post-Pyloric Feeding Tube Placement in a Pediatric Intensive Care Unit

Alonso Marron, Michael Wolf, Marla Levine, Jeremy Boyd et al. • POCUS Journal (2025)

The aim of this study was to investigate the role of point of care ultrasound (POCUS) as an alternative imaging modality to confirm the location of gastric and post-pyloric feeding tubes in patients admitted to the pediatric intensive care ...

DOAJ Open Access (DOAJ) DOI: 10.24908/pocusj.v10i01.17785

Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: a Prospective Pilot Study

Agnese Ozolina, Agnese Ozolina, Marina Sarkele, Marina Sarkele et al. • Frontiers in Medicine (2016)

Introduction: Coagulation and fibrinolysis remain sparsely addressed with regards to acute respiratory distress syndrome (ARDS). We hypothesized that ARDS development might be associated with changes in plasma coagulation and fibrinolysis. ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmed.2016.00064

Establishment of a Pre-vascularized 3D Lung Cancer Model in Fibrin Gel—Influence of Hypoxia and Cancer-Specific Therapeutics

Caroline Kniebs, Caroline Kniebs, Anja Elisabeth Luengen, Anja Elisabeth Luengen et al. • Frontiers in Bioengineering and Biotechnology (2021)

Lung cancer is the most frequently diagnosed cancer worldwide and the one that causes the highest mortality. In order to understand the disease and to develop new treatments, in vitro human lung cancer model systems which imitate the physio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fbioe.2021.761846

Clinical characteristics of and risk factors for secondary bloodstream infection after pneumonia among patients infected with methicillin-resistant Staphylococcus aureus

Fangfang Huang, Ting Shen, Xin Hai, Huiqing Xiu et al. • Heliyon (2022)

Purpose: To investigate the clinical features and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) pneumonia (MP) with secondary MRSA bloodstream infections (MRSA-BSI) (termed MP-BSI) compared with MP alone and to study t...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2022.e11978

Antibacterial activity of selenium nanoparticles/copper oxide (SeNPs/CuO) nanocomposite against some multi-drug resistant clinical pathogens

Ahmed Morad Asaad, Sara A. Saied, Mohammad M. Torayah, N. I. Abu-Elsaad et al. • BMC Microbiology (2025)

Abstract Background Recent advances in nanomedicine have derived novel prospects for development of various bioactive nanoparticles and nanocomposites with significant antibacterial and antifungal properties. This study aims to investigate ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12866-025-03743-9