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Showing 20 of 196 academic articles

A Rare Big Chinese Family With Thrombocytopenia 2: A Case Report and Literature Review

Chengning Tan, Limeng Dai, Zhengqiong Chen, Wuchen Yang et al. • Frontiers in Genetics (2020)

Thrombocytopenia 2 (THC2) is one of the most prevalent forms of inherited thrombocytopenia. It is caused by a heterogeneous group of ANKRD26 gene mutation and shows a heterogeneous clinical and laboratory characteristics. We present a big C...

DOAJ Open Access (DOAJ) DOI: 10.3389/fgene.2020.00340

Progressive suppression of regulated cell death defines terminal macrophage states in liver cirrhosis

Kepu Zheng, Leiyang Dai, Yanghui Wen, Haitao Jiang et al. • Annals of Medicine (2026)

Background Macrophages are central regulators of liver immunity and fibrosis; Recent single-cell studies have characterized macrophage heterogeneity in cirrhosis; however, how regulated cell death programs shape their functional transitions...

DOAJ Open Access (DOAJ) DOI: 10.1080/07853890.2026.2690717

Causal relationship between genetic-predicted uric acid and cervical cancer risk: evidence for nutritional intervention on cervical cancer prevention

Chunge Cao, Dajun Cai, Hao Liu, Xia Zhang et al. • Frontiers in Nutrition (2024)

IntroductionThe relationship between serum uric acid (SUA) and cervical cancer is inconclusive. This study aims to investigate the causal relationship between SUA levels and cervical cancer incidence, and to evaluate the potential role of n...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnut.2024.1464046

Genetics of Obesity

Claude Bouchard, Louis Përusse • Annual Review of Nutrition (1993)

Genetics of Human Obesities: Introductory Notes (C. Bouchard). Etiology and Prevalence of Obesity (G.A. Bray). Nongenetic Determinants of Obesity and Body Fat Topography (J.O. Hill, M.J. Pagliassotti, and J.C. Peters). Overview of the Adopt...

OPENALEX DOI: https://doi.org/10.1146/annurev.nu.13.070193.002005

CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression

Wei Yan, Guo-hui Xiao, Li-juan Wang, Yan Zhou et al. • Journal of Translational Medicine (2025)

Abstract Background The stiffness of the matrix is closely related to the progression of hepatocellular carcinoma (HCC). Although direct targeting of stromal rigidity in HCC remains a clinical challenge, cancer-associated fibroblasts (CAFs)...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12967-025-06325-5

A110

T. Malivanova, E. Skoromyslova, N. Mazurenko • EJC Supplements (2015)

Tumor necrosis factor alpha (TNF) is a multifunctional cytokine, which possesses various biologic functions depending on the type of the cells and the physiological context. TNF is synthesized by immune cells as well as malignant cells. Acc...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ejcsup.2015.08.063

Real-time perioperative communication technologies for reducing family anxiety: a systematic review

Edi Wibowo, Saryono Saryono • Media Keperawatan Indonesia (2026)

Family members often experience anxiety during the intraoperative period because of uncertainty regarding surgical progress and the patient’s condition. Real-time perioperative communication technologies, including mobile applications, auto...

DOAJ Open Access (DOAJ) DOI: 10.26714/mki.9.3.2026.301-311

AN INVESTIGATION OF LOCAL EFFECTS ON SURFACE WARMING WITH GEOGRAPHICALLY WEIGHTED REGRESSION (GWR)

Y. Xue, T. Fung, J. Tsou • The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences (2012)

Urban warming is sensitive to the nature (thermal properties, including albedo, water content, heat capacity and thermal conductivity) and the placement (surface geometry or urban topography) of urban surface. In the literature the spatial ...

DOAJ Open Access (DOAJ) DOI: 10.5194/isprsarchives-XXXIX-B8-131-2012

Spatiotemporal variation of the ecosystem service value in China based on surface area

Chaohui Yin, Qingsong He, Peng Xie, Yanfang Liu et al. • Ecological Indicators (2023)

The assessment of ecological assets is of great significance for protecting and using ecological resources. Traditional methods of ecological assets assessment, which adopt the planar area as the standard, often ignore the impact of the sur...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.ecolind.2023.110067

Protocol for the Tallaght University Hospital Institute for Memory and Cognition-Biobank for Research in Ageing and Neurodegeneration

Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight et al. • BMJ Open (2023)

Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the un...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2023-077772

Heterogeneity in Trajectories of Body Mass Index and Their Associations with Mortality in Old Age: A Literature Review

Hiroshi Murayama, Benjamin A. Shaw • Journal of Obesity & Metabolic Syndrome (2017)

This article reviewed studies to investigate the association between trajectories of body mass index (BMI) and mortality among older adults. Investigators conducted a systematic search of published peer-reviewed literature in the PubMed dat...

DOAJ Open Access (DOAJ) DOI: 10.7570/jomes.2017.26.3.181

Drivers of municipal waste generation in Nordic countries: panel evidence

Mohammad Ridwan, Zulfiquar Ali Antor, Jeremy Ko, Mohammad Haseeb et al. • Waste Management Bulletin (2026)

Municipal waste generation remains a persistent sustainability challenge, even in countries with strong environmental governance and circular economy ambitions. Yet it remains unclear how affluence, household final consumption expenditure a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.wmb.2026.100394