Academic Articles & Research Papers

In vitro inhibition of SARS-CoV-2 Infection by dry algae powders

Abstract Chlorella spp., Spirulina spp., and fucoidan dry powders, are commercialized as food supplements and are considered safe for human consumption. Their broad-spectrum antiviral properties have been studied, however, their effect agai...

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

Abstract The SARS-CoV-2 virus caused the most severe pandemic around the world, and vaccine development for urgent use became a crucial issue. Inactivated virus formulated vaccines such as Hepatitis A and smallpox proved to be reliable appr...

Role of N343 glycosylation on the SARS-CoV-2 S RBD structure and co-receptor binding across variants of concern

Glycosylation of the SARS-CoV-2 spike (S) protein represents a key target for viral evolution because it affects both viral evasion and fitness. Successful variations in the glycan shield are difficult to achieve though, as protein glycosyl...

The Psychosocial Impact of the Romanian Government Measures on the Population During the COVID-19 Pandemic

The Covid-19 pandemic generated a global crisis involving most countries in the world. State governments worldwide were forced to take appropriate measures impacting different fields. The Romanian government and other local public authoriti...

A Model of Social Distancing for Interacting Age-Distributed Multi-Populations: An Analysis of Students’ In-Person Return to Schools

Because of the current scenario of the SARS-CoV-2 (COVID-19) pandemic in Brazil, whose vaccination campaign is in the initial stage, government authorities have pointed out towards the complete reopening of the economy. And recently for the...

Lessons Learned From a Sequential Mixed-Mode Survey Design to Recruit and Collect Data From Case-Control Study Participants: Formative Evaluation

BackgroundSequential mixed-mode surveys using both web-based surveys and telephone interviews are increasingly being used in observational studies and have been shown to have many benefits; however, the application of this survey design has...

The correspondence between the structure of the terrestrial mobility network and the spreading of COVID-19 in Brazil

The inter-cities mobility network is of great importance in understanding outbreaks, especially in Brazil, a continental-dimension country. We adopt the data from the Brazilian Ministry of Health and the terrestrial flow of people between c...

Support for mask use as a COVID-19 public health measure among a large sample of Canadian secondary school students

Abstract Background Youth voice has been largely absent from deliberations regarding public health measures intended to prevent SARS-CoV-2 transmission, despite being one of the populations most impacted by school-based policies. To inform ...

Correction: Dutch participatory surveillance framework for evaluating evolutionary changes on SARS-CoV-2 affecting rapid diagnostic test sensitivity in 2022 − 2023

Co-Regulation of Protein Coding Genes by Transcription Factor and Long Non-Coding RNA in SARS-CoV-2 Infected Cells: An In Silico Analysis

Altered expression of protein coding gene (PCG) and long non-coding RNA (lncRNA) have been identified in SARS-CoV-2 infected cells and tissues from COVID-19 patients. The functional role and mechanism (s) of transcriptional regulation of de...

Human RP105 monoclonal antibody enhances antigen-specific antibody production in unique culture conditions

Summary: Detecting antibodies, particularly those targeting donor human leukocyte antigens in organ transplantation and self-antigens in autoimmune diseases, is crucial for diagnosis and therapy. Radioprotective 105 (RP105), a Toll-like rec...

Recuperação Completa de Doente com Carcinoma da Próstata Estádio IV Durante a Pandemia COVID-19

A doença causada pelo coronavírus (COVID-19), inicialmente descrita em Wuhan, China, foi recentemente declarada pela Organização Mundial da Saúde (OMS) como uma pandemia global. A idade avançada e a presença de comorbilidades, característic...

Mapping inequities in global vaccine sentiment research

Introduction Negative public sentiment towards vaccination (PSV) poses significant challenges to the effectiveness of immunisation programmes, with dramatic effects on morbidity and mortality for vaccine-preventable diseases. Yet, health re...

Tracking discussions of complementary, alternative, and integrative medicine in the context of the COVID-19 pandemic: a month-by-month sentiment analysis of Twitter data

Abstract Background Coronavirus disease 2019 (COVID-19) is a novel infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite the paucity of evidence, various complementary, alternative and integr...

Distinct T cell correlates of COVID-19 risk before and after a second booster in previously SARS-CoV-2 infected versus naïve COVAIL trial participants.

A web-based artificial intelligence system for label-free virus classification and detection of cytopathic effects

Abstract Identifying viral replication within cells demands labor-intensive isolation methods, requiring specialized personnel and additional confirmatory tests. To facilitate this process, we developed an AI-powered automated system called...