Academic Articles & Research Papers

Alterations in Hip and Knee Joint Contact Force Waveforms and Orientation Induced by Gait Modifications: A Case Study

Introduction & Purpose Idiopathic torsional deformities of lower limb bones can affect a patient’s gait pattern and joint health, while their cause remains unidentified (Koller et al., 2026). Abnormal joint loadings and the progression of ...

Molecular detection of antibiotic resistance genes in Staphylococcus aureus isolated from poultry farms of Kathmandu Valley, Nepal

Abstract Background Antimicrobial resistance (AMR) has emerged as a critical global health challenge and is currently addressed through a “One Health” approach that investigates its occurrence in humans, animals, and the environment, as wel...

Transmission of β-lactamases in the pork food chain: A public health concern

Antimicrobial resistance (AMR) is a risk for public health that requires management in a One Health perspective, including humans, animals, and the environment. The food production chain has been identified as a possible route of transmissi...

Correction to: Evaluating a screener to quantify PTSD risk using emergency care information: a proof of concept study

An amendment to this paper has been published and can be accessed via the original article....

Outbreaks of human respiratory syncytial virus in wild gorillas highlight the importance of prevention measures and integrated surveillance for risk mitigation

Transmission of human respiratory pathogens to wild, human-habituated great apes has been repeatedly documented within research and tourism projects. While the implementation of hygiene measures has significantly reduced the risk of pathoge...

The Vibrio vulnificus stressosome is an oxygen-sensor involved in regulating iron metabolism

A cryo-electron microscopy reconstruction of a stressosome complex from a Gram-negative bacterium, Vibrio vulnificus, reveals variations in subunit composition and symmetry, which could serve to adjust the activation threshold in the respon...

Angiogenesis as a Survival Mechanism in Heartworm Disease: The Role of Fructose-Bisphosphate Aldolase and Actin from <i>Dirofilaria immitis</i> in an In Vitro Endothelial Model

Heartworm disease, caused by Dirofilaria immitis, is a vector-borne zoonotic disease, (mainly affecting canids and felids) causing chronic vascular and pulmonary pathology in its early stages, which worsens with parasite load and/or death o...

Chitosan nanoparticles as next-generation carriers for veterinary DNA vaccines: Mechanisms, immune responses, and translational prospects

Background and Aim: Chitosan-based DNA nanoparticles have emerged as a promising next-generation platform for veterinary vaccines, addressing several limitations of conventional attenuated, inactivated, and recombinant formulations. Chitosa...

LADS: a powerful vaccine platform for cancer immunotherapy and prevention

Abstract Background The intracellular bacterium Listeria monocytogenes is an attractive vector for cancer immunotherapy as it can effectively deliver tumor antigens to antigen-presenting cells, leading to a robust antitumor response. Result...

Corrigendum: New Sesquiterpenoids From Plant-Associated Irpex lacteus

MBPD: A multiple bacterial pathogen detection pipeline for One Health practices

Abstract Bacterial pathogens are one of the major threats to biosafety and environmental health, and advanced assessment is a prerequisite to combating bacterial pathogens. Currently, 16S rRNA gene sequencing is efficient in the open‐view d...

Preparedness of health facilities in managing hypertension & diabetes mellitus in Kilimanjaro, Tanzania: a cross sectional study

Abstract Background Hypertension and Diabetes mellitus are risk factors for cardiovascular diseases that cause 17 million deaths globally. Many of these deaths could have been prevented if hypertensive and diabetic patients had their blood ...

Developing and defining core climate and environmental epidemiology competencies for field epidemiology training programs in the Eastern Mediterranean Region: a Delphi study

BackgroundClimate change, environmental degradation, and chemical hazards increasingly shape population health risks, particularly in the Eastern Mediterranean Region (EMR), where water scarcity, rapid urbanization, conflict, and fragile he...

Rethinking avian influenza control: a systems-oriented One Health perspective for family poultry

Early detection and control of high- and low-pathogenicity avian influenza (HPAI, LPAI) in family poultry flocks remain challenging in settings where mortality from enzootic diseases such as Newcastle disease (ND) and infectious bursal dise...

Mpox as Two Global Health Emergencies: Altered Transmission, Genomics, Clinical Manifestation and Public Health Impact

Mpox virus (MPXV) is the only pathogen that triggered two Public Health Emergency of International Concern (PHEIC) declarations, first in July 2022 and then again in August 2024. The 2022 outbreak was attributed primarily to clade IIb MPXV,...

Toll-like receptor 2 coordinates induction of IL-22 in lung macrophages following organic dust-induced inflammation

IntroductionOrganic dust exposures, particularly in occupational settings, induce airway inflammation and contribute to the development and progression of chronic lung disease and impaired tissue regeneration. Interleukin-22 (IL-22) is a pl...

Burden and transmission dynamics of paediatric antimicrobial resistance in Benin City, Nigeria: a One Health study protocol.

Assessing the Microbial Quality of Shrimp (<i>Xiphonaeus kroyeri)</i> and Mussels (<i>Perna perna</i>) Illegally Sold in the Vitória Region, Brazil, and Investigating the Antimicrobial Resistance of <i>Escherichia coli</i> Isolates

The consumption of seafood is crucial for food security, but poor hygiene along the food production chain can result in low microbiological quality, posing significant risks for public health and seafood quality. Thus, this study aimed to a...

Machine learning in breast MRI

Machine-learning techniques have led to remarkable advances in data extraction and analysis of medical imaging. Applications of machine learning to breast MRI continue to expand rapidly as increasingly accurate 3D breast and lesion segmenta...

History of artificial intelligence in medicine