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Identification and Functional Assessment of the First Placental Adhesin of Treponema pallidum That May Play Critical Role in Congenital Syphilis

Shekerah Primus, Sandra C. Rocha, Lorenzo Giacani, Lorenzo Giacani et al. • Frontiers in Microbiology (2020)

Syphilis is a global, re-emerging sexually transmitted infection and congenital syphilis remains a major cause of adverse pregnancy outcomes due to bacterial infection in developing nations with a high rate of fetus loss. The molecular mech...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2020.621654

CRISPR/Cas9 for hepatitis B virus infection treatment

Bo Cai, Shixue Chang, Yuhan Tian, Shuai Zhen • Immunity, Inflammation and Disease (2023)

Abstract Hepatitis B virus (HBV) infection remains a global health challenge. Despite the availability of effective preventive vaccines, millions of people are at risk of cirrhosis and hepatocellular carcinoma. Current drug therapies inhibi...

DOAJ Open Access (DOAJ) DOI: 10.1002/iid3.866

Genomic evolution and stability of the mcr-1-harboring IncI2 plasmid in the presence and absence of colistin

Cong Shen, Meina Wu, Minxuan Su, Hao Wu et al. • BMC Genomics (2025)

Abstract Background The emergence of plasmid-mediated colistin resistance, primarily driven by the mcr-1 gene, represents a major global health threat. IncI2 plasmids, one of the leading carriers of mcr-1, have been frequently recovered fro...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12864-025-12325-y

Molecular detection of antibiotic resistance genes in Staphylococcus aureus isolated from poultry farms of Kathmandu Valley, Nepal

Padma Shrestha, Bijay Bajracharya, Deena Shrestha, Ajit Kumar Karna et al. • BMC Microbiology (2026)

Abstract Background Antimicrobial resistance (AMR) has emerged as a critical global health challenge and is currently addressed through a “One Health” approach that investigates its occurrence in humans, animals, and the environment, as wel...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12866-026-04713-5

Socioeconomic inequalities in effective service coverage for reproductive, maternal, newborn, and child health: a comparative analysis of 39 low-income and middle-income countries

Kanya Anindya, Tiara Marthias, Sukumar Vellakkal, Natalie Carvalho et al. • EClinicalMedicine (2021)

Background: Reducing socioeconomic inequalities in access to good quality health care is key for countries to achieve Universal Health Coverage. This study aims to assess socioeconomic inequalities in effective coverage of reproductive, mat...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.eclinm.2021.101103

Elevated Eosinophils as a Feature of Inflammation Associated With Hypertension in Virally Suppressed People Living With HIV

Sepiso K. Masenga, Fernando Elijovich, Benson M. Hamooya, Selestine Nzala et al. • Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (2020)

Background People living with HIV (PLWH) are at increased risk of cardiovascular disease, including hypertension, which persists despite effective plasma viral suppression on antiretroviral therapy. HIV infection is characterized by long‐te...

DOAJ Open Access (DOAJ) DOI: 10.1161/JAHA.118.011450