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Sedative-hypnotic drug use and risk of falls and fractures in elderly patients: a cross-sectional study

Mohammad Hossein Imani, Amir Hossein Imani, Amirhossein Saem, Maryam Niksolat • BMC Geriatrics (2025)

Abstract Background Falls are a leading cause of injury, hospitalization, and mortality among older adults. Sedative-hypnotic medications, especially benzodiazepines and Z-drugs, have been implicated as potential contributors to fall risk a...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-025-06624-y

Facial Oedema Is Not Always Angioedema: A Case of Spontaneous Pneumomediastinum with Subcutaneous Emphysema during COPD Exacerbation

Sarah Damanti, Francesca Rosini, Daniela Mari, Maura Marcucci • European Journal of Case Reports in Internal Medicine (2015)

We report a case of acute facial oedema in an elderly hospitalized patient which was initially misdiagnosed as angioedema secondary to antibiotics in a patient with an allergic diathesis. We describe the differential aetiologies and then t...

DOAJ Open Access (DOAJ) DOI: 10.12890/2015_000281

Procalcitonin-guided antibiotic therapy for pediatrics with infective disease: A updated meta-analyses and trial sequential analysis

Peng Li, JiaLe Liu, Junjun Liu • Frontiers in Cellular and Infection Microbiology (2022)

ObjectiveWe aimed to evaluate the effect of procalcitonin (PCT) guided therapy on antibiotic exposure in pediatric patients with infectious disease.MethodsWe performed an updated systematic review and meta-analysis of randomized controlled ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fcimb.2022.915463

The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists

Valerio Nardone, Federica Marmorino, Marco Maria Germani, Natalia Cichowska-Cwalińska et al. • Current Oncology (2024)

The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in per...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol31090369

Why did an effective Dutch complex psycho-social intervention for people with dementia not work in the German healthcare context? Lessons learnt from a process evaluation alongside a multicentre RCT

Sebastian Voigt-Radloff, Maud Graff, Myrra Vernooij-Dassen, Rainer Leonhart et al. • BMJ Open (2011)

Background The positive effects of the Dutch Community Occupational Therapy in Dementia programme on patients' daily functioning were not found in a multicentre randomised controlled trial (RCT) in Germany.Objectives To evaluate possible ef...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2011-000094

Constructing the concept of healthy ageing and examining its association with loneliness in older adults

Ivy Yan Zhao, Mu-Hsing Ho, Stefanos Tyrovolas, Sasha Yuanjie Deng et al. • BMC Geriatrics (2023)

Abstract Background World Health Organization (WHO) has defined healthy ageing by highlighting five functional ability domains to (meet basic needs, make decisions, be mobile, build and maintain relationships, and contribute to society), wh...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-04019-5

Association of negative opinions towards telepsychiatry with its prior use and the level of geriatric psychiatry care among nursing home stakeholders

S Pirbay, MD, S Abou Kassm, MD, MPH, C Di-Maggio, MD, F Naudet, MD, PhD et al. • Archives of Gerontology and Geriatrics Plus (2025)

Objectives: Despite the benefits of geriatric telepsychiatry, the lack of support from the staff remains one of the major challenges it faces. We wanted to explore whether negative opinions towards telepsychiatry in nursing home (NH) stakeh...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2025.100150

Single-cell RNA sequencing to detect age-associated genes that identify senescent cells in the liver of aged mice

Yuta Doshida, Shinichi Hashimoto, Sadahiro Iwabuchi, Yuka Takino et al. • Scientific Reports (2023)

Abstract Senescent cells are predicted to occur and increase in animal tissues with aging. However, senescent cells in the tissues of aged animals remain to be identified. We refer to the marker genes to identify senescent cells in tissues ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-41352-6

Local, collaborative, stepped, and personalized care management for older people with chronic diseases – results from the randomized controlled LoChro-trial

Gloria Metzner, Lukas Maximilian Horstmeier, Jürgen Bengel, Eva Maria Bitzer et al. • BMC Geriatrics (2023)

Abstract Background In the aging population of Western societies, an increasing number of older adults have multiple chronic diseases. As multifaceted health problems imply the involvement of several healthcare professionals, multimorbid ol...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-03797-2

The burden and determinants of cognitive impairment among individuals with chronic diseases in Ethiopia: A systematic review and meta-analysis

Addisu Getie, Melaku Bimerew, Mihretie Gedfew, Baye Tsegaye Amlak et al. • Archives of Gerontology and Geriatrics Plus (2025)

Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2025.100171

Impact of the Age of Cecal Material Transfer Donors on Alzheimer’s Disease Pathology in 5xFAD Mice

Francesco Valeri, Malena dos Santos Guilherme, Fuqian He, Nicolai M. Stoye et al. • Microorganisms (2021)

Alzheimer’s disease is a progressive neurodegenerative disorder affecting around 30 million patients worldwide. The predominant sporadic variant remains enigmatic as the underlying cause has still not been identified. Since efficient therap...

DOAJ Open Access (DOAJ) DOI: 10.3390/microorganisms9122548

Nutritional status, literacy, and risk factors of malnutrition in the population over 50 years of age - findings from the SHARE project

Tereza Vágnerová, Olga Dvořáčková, Eva Topinková • Clinical Nutrition Open Science (2024)

Summary: Background & Aims: The transition from middle age to old age (from adults aged 50–55 years to older seniors aged 75–80 years) represents a critical period in terms of changes in body composition, i.e., increase in body fat per...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.nutos.2024.01.006

HEART Camp Connect—Promoting adherence to exercise in adults with heart failure with preserved ejection fraction

Windy W. Alonso, Sara E. Bills, Scott W. Lundgren, Steven J. Keteyian et al. • ESC Heart Failure (2025)

Abstract Aims Most adults with stable heart failure are safe to exercise at a moderate intensity for 150 min/week. Regular participation in exercise may improve outcomes in adults with heart failure with preserved ejection fraction (HFpEF)....

DOAJ Open Access (DOAJ) DOI: 10.1002/ehf2.15341

Broca’s biases in modern aphasiology

Silvia Martínez-Ferreiro, Monica I. Norvik, Monica I. Norvik • Frontiers in Human Neuroscience (2026)

Broca’s description of aphemia signals the emergence of aphasiology as a discipline. It also marks the beginning of a long tradition of studies of right-handed patients (“Nous parlons avec l’hémisphère gauche”) with lesions in the inferior ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnhum.2026.1783073

Physician assistants in geriatric medical care

Andrzej Kozikowski, Trenton Honda, Freddi Segal-Gidan, Roderick S. Hooker • BMC Geriatrics (2020)

Abstract Background The US population is maturing. As of 2020, over 52 million (16%) people are age 65 or older. With a citizenry that is increasingly “gray,” the nation is short of medical providers who specialize in geriatric medical care...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-020-01831-1

A review of studies that used B mode ultrasound to estimate age-related changes in anterior thigh skeletal muscle thickness across the adult lifespan

Isobel Jacob, Gareth Jones, Peter Francis, Mark I Johnson • Archives of Gerontology and Geriatrics Plus (2024)

Background: The purpose of this review was to synthesise and determine the age-related change per annum in muscle thickness of the anterior thigh across the adult lifespan. Methods: Electronic databases (PubMed, SPORTDiscus and MEDLINE) wer...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2024.100037

Lipid profile in elderly and centenarian subjects in Kazakhstan: a case-control study

Yu. Ganzhula, Zh. Borykbay, V. Tkachev, S. Urazova et al. • Central Asian Journal of Medical Hypotheses and Ethics (2024)

Introduction. The health of centenarians is a major focus in global studies. Dyslipidemia is directly linked to the risk of cardiovascular diseases, which pose a growing burden on healthcare due to the increasing elderly population. Studyin...

DOAJ Open Access (DOAJ) DOI: 10.47316/cajmhe.2024.5.3.04

Effectiveness of a tele-rehabilitation intervention to improve performance and reduce morbidity for people post hip fracture - study protocol for a randomized controlled trial

Yafit Gilboa, Talia Maeir, Sharon Karni, Michal E. Eisenberg et al. • BMC Geriatrics (2019)

Abstract Background Most surviving hip-fracture patients experience reduced mobility and lose some of their functional ability, which increases the risk of complications and rehospitalization. Post-discharge transitional programs to reduce ...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-019-1141-z