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Atorvastatin suppresses high-risk colorectal adenomas via reprogramming of lipid metabolism and Inhibition of stemness

Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports (2025)

Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-32406-y

Grain boundary and texture evolution of TiB/Ti–2Al–6Sn titanium matrix composite under electroshocking treatment

Yaya Wu, Yan Wen, Anan Guo, Jian Zhou et al. • Journal of Materials Research and Technology (2023)

This work used electroshocking treatment (EST) plus external loading to regulate the microstructure of titanium matrix composites (TMCs). The external loading was 0.3 MPa. After EST plus external loading with 0.3 MPa, the α was reduced to 2...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jmrt.2023.10.177

A Proactive Collision Avoidance Model for Connected and Autonomous Vehicles in Mixed Traffic Flow

Guojing Hu, Kun Li, Weike Lu, Ouchan Chen et al. • World Electric Vehicle Journal (2025)

Collision avoidance between vehicles is a great challenge, especially in the context of mixed driving of connected and autonomous vehicles (CAVs) and human-driven vehicles (HVs). Advances in automation and connectivity technologies provide ...

DOAJ Open Access (DOAJ) DOI: 10.3390/wevj16070394

Faculty perceptions of a professional development program for developing CUREs and promoting inclusive and equitable teaching

Laura Gough, Rommel Miranda, Matthew Hemm, Leann Norman et al. • Journal of Microbiology & Biology Education (2025)

ABSTRACT The Diffusion of Innovations (DOI) model can be used to explore how faculty prioritize learning about and adopting new pedagogical approaches. Here, we use the DOI framework to contextualize biology faculty perceptions of a profess...

DOAJ Open Access (DOAJ) DOI: 10.1128/jmbe.00215-24

Pt and CoB trilayer Josephson $$\pi $$ π junctions with perpendicular magnetic anisotropy

N. Satchell, T. Mitchell, P. M. Shepley, E. Darwin et al. • Scientific Reports (2021)

Abstract We report on the electrical transport properties of Nb based Josephson junctions with Pt/Co $$_{68}$$ 68 B $$_{32}$$ 32 /Pt ferromagnetic barriers. The barriers exhibit perpendicular magnetic anisotropy, which has the main advantag...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-021-90432-y

Evaluating key predictors of breast cancer through survival: a comparison of AFT frailty models with LASSO, ridge, and elastic net regularization

Senyefia Bosson-Amedenu, Emmanuel Ayitey, Francis Ayiah-Mensah, Luyton Asare • BMC Cancer (2025)

Abstract Background Frailty models are extensively utilized in survival analysis to address unobserved heterogeneity among individuals. However, selecting the most robust model for survival prediction, especially in the context of high-dime...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12885-025-14040-z

Ethical and social implications of approaching death prediction in humans - when the biology of ageing meets existential issues

Marie Gaille, Marco Araneda, Clément Dubost, Clémence Guillermain et al. • BMC Medical Ethics (2020)

Abstract Background The discovery of biomarkers of ageing has led to the development of predictors of impending natural death and has paved the way for personalised estimation of the risk of death in the general population. This study inten...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12910-020-00502-5

Cost of inaction: a framework to estimate the economic cost of missing a patient with tuberculosis in the Indian context

Salmaan Keshavjee, Meredith B Brooks, Tom Nicholson, Viswanath Pingali • BMJ Open (2023)

Objectives To estimate the economic impact of failure to find and treat tuberculosis disease and prevent tuberculosis infection from progressing to active disease.Design Estimating the economic cost of not finding and treating a patient suf...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2022-070717

Response Surface Analysis: A Tutorial for Examining Linear and Curvilinear Effects

Antonio Carlos Rodrigues • RAC: Revista de Administração Contemporânea (2021)

Context: response surface analysis (RSA) is an approach that allows examining the extent to which combinations of two predictive variables relate to one outcome variable. The method is particularly interesting in cases where (in)congruence ...

DOAJ Open Access (DOAJ) DOI: 10.1590/1982-7849rac2021200293.en

Improvement of the external municipal financial control system in the context of public authority reform

S. M. Mironova, A. I. Mordvintsev, I. A. Eremenko • Правоприменение (2021)

The subject. The implementation of external municipal financial control cannot be called fully competent in Russia. Many practical problems are currently being addressed mainly through the transfer of powers to implement external financial ...

DOAJ Open Access (DOAJ) DOI: 10.52468/2542-1514.2021.5(1).96-107

Habitat availability shapes composition and climate change response of alpine butterfly communities

Korbinian Schrauth, Matthias Plattner, Jörg Müller, Jérôme Pellet • Alpine Entomology (2026)

Climate change is known to cause range shifts to higher elevations in mountainous regions. Butterflies are especially sensitive to changes in environmental conditions and their response to climate change has been extensively studied. Howeve...

DOAJ Open Access (DOAJ) DOI: 10.3897/alpento.10.186978

Authorial Narratives in the Work of Middle Eastern Directors

Галина Погребняк • Вісник Київського національного університету культури і мистецтв. Серія: Аудіовізуальне мистецтво і виробництво (2024)

The purpose of the research is to identify relevant narratives in the work of directors-authors of Middle Eastern cinema and its functioning in the space of international film festivals. Research methodology. The analytical method was used ...

DOAJ Open Access (DOAJ) DOI: 10.31866/2617-2674.7.2.2024.318991