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Showing 20 of 2,024 academic articles

The Industrial Design Collection

Christian Wölfel, Jens Krzywinski (2024)

Industrial design at TUD Dresden University of Technology prioritizes human needs and experiencing in designing complex novel systems for desirable futures. For this purpose, it integrates human-centred design, engineering and social scienc...

OPENALEX cc-by-nc-nd DOI: https://doi.org/10.25368/2024.254

Industrial Design - New Frontiers

Denis Alves Coelho • InTech eBooks (2011)

A new breed of modern designers is on the way. These non-traditional industrial designers work across disciplines, understand human beings, as well as business and technology thus bridging the gap between customer needs and technological ad...

OPENALEX Open Access DOI: https://doi.org/10.5772/849

Protocol for the Tallaght University Hospital Institute for Memory and Cognition-Biobank for Research in Ageing and Neurodegeneration

Eimear Connolly, Shane Lyons, Cliona O’Farrelly, Graham Knight et al. • BMJ Open (2023)

Introduction Alzheimer’s disease and other dementias affect >50 million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort and biobank studies have played a critical role in advancing the un...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2023-077772

Associations between Lifestyle Factors and Vitamin E Metabolites in the General Population

Leon G. Martens, Jiao Luo, Fleur L. Meulmeester, Nadia Ashrafi et al. • Antioxidants (2020)

The antioxidant vitamin E (α-tocopherol, α-TOH) protects lipids from oxidation by reactive oxygen species. We hypothesized that lifestyle factors associate with vitamin E metabolism marked by urinary α-tocopheronolactone hydroquinone (α-TLH...

DOAJ Open Access (DOAJ) DOI: 10.3390/antiox9121280

Stage-Dependent Within-Individual Comparison Reveals SIV-Specific Activation/Exhaustion Shift in Rhesus Macaques

Ling Tong, Zhe Cong, Long Tian, Jingjing Zhang et al. • Frontiers in Microbiology (2021)

It is challenging to trace the complicated individual-based variations of HIV-specific immunocompetence shift during the successful antiretroviral therapy (ART) era. Using eight rhesus monkeys simulating a longitudinal stage-dependent cohor...

DOAJ Open Access (DOAJ) DOI: 10.3389/fmicb.2021.704449

Advances in the Development of PET Ligands Targeting Histone Deacetylases for the Assessment of Neurodegenerative Diseases

Tetsuro Tago, Jun Toyohara • Molecules (2018)

Epigenetic alterations of gene expression have emerged as a key factor in several neurodegenerative diseases. In particular, inhibitors targeting histone deacetylases (HDACs), which are enzymes responsible for deacetylation of histones and ...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules23020300

Correlation between frailty and reduction in cortical thickness in patients with chronic obstructive pulmonary disease

Ayumi Fukatsu-Chikumoto, Tsunahiko Hirano, Shun Takahashi, Takuya Ishida et al. • Scientific Reports (2024)

Abstract Physical inactivity and cognitive impairment in patients with chronic obstructive pulmonary disease (COPD) can lead to frailty and poor prognoses. However, little is known regarding the association between frailty and the human bra...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-024-53933-0

The Gerontological Imagination: Social Influences on the Development of Gerontology, 1945-Present

Carroll L. Estes, Elizabeth A. Binney, Richard Culbertson • The International Journal of Aging and Human Development (1992)

This article presents a framework for the analysis of the development of gerontology since 1945. Three distinct historical periods and several forces that have shaped the field are examined. These forces reside in the political, economic, s...

OPENALEX DOI: https://doi.org/10.2190/ywl3-wx80-um2u-yeun

Gerontology

L. K. Frank • Journal of Gerontology (1946)

With millions of men and women growing older, baffled by changes in themselves and in the world around them, the country has a definite need for not only large scale provisions for their care but also for a specific and individual service f...

OPENALEX DOI: https://doi.org/10.1093/geronj/1.1_part_1.1

The Challenge of Cultural Gerontology

Julia Twigg, Wendy E. Martin • The Gerontologist (2014)

Over the last decade, Cultural Gerontology has emerged as one of the most vibrant elements of writing about age (Twigg, J., & Martin, W. (Eds.) (2015). The Routledge handbook of cultural gerontology. London: Routledge). Reflecting the wider...

OPENALEX DOI: https://doi.org/10.1093/geront/gnu061

Routledge Handbook of Cultural Gerontology

Julia Twigg • Routledge eBooks (2015)

Later years are changing under the impact of demographic, social and cultural shifts. No longer confined to the sphere of social welfare, they are now studied within a wider cultural framework that encompasses new experiences and new modes ...

OPENALEX DOI: https://doi.org/10.4324/9780203097090

Qualitative Gerontology

Martha Holstein • Research on Aging (1995)

This commentary examines four articles in qualitative and humanistic gerontology, with the purpose of explicating the goals of such work, the criteria that make them exemplary, and the contribution they make to an enriched understanding of ...

OPENALEX DOI: https://doi.org/10.1177/0164027595171006

Materials for Total Hip Joint Prostheses: Biaxial Flexural Strength of Two Ceramic Systems

Bojana TABAKOVA, Ivanka KALIMANOVA, Ina YANKOVA, Hristiana NIKOLOVA • The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science (2010)

Total hip joint replacement is one of the most successful orthopaedic surgeries in the last decade. Essential part of total hip joint prostheses is the mobile joint “hemispherical head - hemispherical cup”. Functional properties and durabil...

DOAJ Open Access (DOAJ)

Casearia tomentosa fruit extracts exposed larvicidal activity and morphological alterations in Culex quinquefasciatus and Aedes albopictus under in vitro and semi field conditions

Priyanka Mandal, Goutam Chandra • BMC Research Notes (2024)

Abstract Mosquitoes are notorious insects that transmit a wide range of infectious diseases, including zika, malaria, chikungunya, filariasis, and dengue. The overuse and incorrect application of synthetic pesticides to control mosquitoes h...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13104-023-06663-x

Nanotechnology’s frontier in combatting infectious and inflammatory diseases: prevention and treatment

Yujing Huang, Xiaohan Guo, Yi Wu, Xingyu Chen et al. • Signal Transduction and Targeted Therapy (2024)

Abstract Inflammation-associated diseases encompass a range of infectious diseases and non-infectious inflammatory diseases, which continuously pose one of the most serious threats to human health, attributed to factors such as the emergenc...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41392-024-01745-z

MiR-200c synergizes with trastuzumab-loaded gold nanoparticles to overcome resistance in ovarian cancer cells

Tommaso A. Salamone, Sofia Marotta, Stella Mrmić, Salvatore Raffa et al. • Cancer Nanotechnology (2025)

Abstract Background Trastuzumab (TZ) resistance remains a significant challenge in the treatment of human epidermal growth factor receptor 2 (HER2)-positive epithelial ovarian cancer (EOC), necessitating novel therapeutic strategies to impr...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12645-025-00330-5

Nanotechnology for Plant Disease Management

Elizabeth A. Worrall, Aflaq Hamid, Karishma T. Mody, Neena Mitter et al. • Agronomy (2018)

Each year, 20%–40% of crops are lost due to plant pests and pathogens. Existing plant disease management relies predominantly on toxic pesticides that are potentially harmful to humans and the environment. Nanotechnology can offer advantage...

OPENALEX cc-by DOI: https://doi.org/10.3390/agronomy8120285