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Gallium nanoparticles along with low-dose gamma radiation modulate TGF-β/MMP-9 expression in hepatocellular carcinogenesis in rats

Fatma SM Moawed, Sawsan M El-Sonbaty, Somaya Z Mansour • Tumor Biology (2019)

Combining chemotherapy with radiotherapy potentiates the outcome of cancer treatment for the more comprehensive attack. In the current study, we continued to assess the therapeutic efficaciousness of the newly synthesized gallium nanopartic...

DOAJ Open Access (DOAJ) DOI: 10.1177/1010428319834856

Identification of Eusynstyelamide B as a Potent Cell Cycle Inhibitor Following the Generation and Screening of an Ascidian-Derived Extract Library Using a Real Time Cell Analyzer

Michelle S. Liberio, Martin C. Sadowski, Colleen C. Nelson, Rohan A. Davis • Marine Drugs (2014)

Ascidians are marine invertebrates that have been a source of numerous cytotoxic compounds. Of the first six marine-derived drugs that made anticancer clinical trials, three originated from ascidian specimens. In order to identify new anti-...

DOAJ Open Access (DOAJ) DOI: 10.3390/md12105222

Digital health technologies and major depressive disorder

Roger S. McIntyre, Walter Greenleaf, Grzegorz W. Bulaj, Steven T. Taylor et al. • CNS Spectrums (2023)

There is an urgent need to improve the clinical management of major depressive disorder (MDD), which has become increasingly prevalent over the past two decades. Several gaps and challenges in the awareness, detection, treatment, and monito...

OPENALEX cc-by-nc DOI: https://doi.org/10.1017/s1092852923002225

Health Technology Assessment

Lise Lund Håheim, Berit Mørland • IGI Global eBooks (2011)

Scientific publications in medical fields are rapidly increasing and are overwhelming in numbers. This poses a challenge to health authorities, and health professionals who need knowledge to make informed decisions in finding the best evide...

OPENALEX DOI: https://doi.org/10.4018/978-1-60566-988-5.ch003

Health technology assessment and haemophilia

Albert Farrugia, Brian O’Mahony, Josephine Cassar • Haemophilia (2012)

Although the funding of rare diseases such as haemophilia in developing countries remains a low priority, pressures on the funding of haemophilia treatment are also emerging in developed economies affected by the global economic downturn an...

OPENALEX DOI: https://doi.org/10.1111/j.1365-2516.2012.02754.x

Feasibility study for interactive reporting of network meta-analysis: experiences from the development of the MetaInsight COVID-19 app for stakeholder exploration, re-analysis and sensitivity analysis from living systematic reviews

Yiqiao Xin, Clareece R. Nevill, Janion Nevill, Ewan Gray et al. • BMC Medical Research Methodology (2022)

Abstract Background Network meta-analysis (NMA) has been increasingly adopted worldwide by Cochrane reviews, guideline developers and decision-making bodies to identify optimal treatment choices. However, NMA results are often produced stat...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12874-022-01507-x

Neurotoxicity of PM<sub>2.5</sub>-Bound Multi-Pollutant Mixtures in Parkinson’s Disease: Exploring the <i>INPP5D</i>/SHIP1-PI3K-AKT Axis via an Integrative Multi-Omics Study

Lufei Chen, Chaoxian Dai, Zhenfang Wu, Yuhan Lin et al. • Journal of Xenobiotics (2026)

Accumulating epidemiological evidence links ambient PM2.5 exposure to elevated Parkinson’s disease (PD) risk, yet the neurotoxicity triggered by PM2.5 multi-pollutant mixtures under real co-exposure scenarios remains insufficiently elucidat...

DOAJ Open Access (DOAJ) DOI: 10.3390/jox16060184

The efficacy of Narrative Exposure Therapy for Children (KIDNET) as a treatment for traumatized young refugees versus treatment as usual: update to the study protocol for the multi-center randomized controlled trial YOURTREAT

Jasmin Wittmann, Melissa Groß, Claudia Catani, Telja Schmidt et al. • Trials (2022)

Abstract Background The trial YOURTREAT aims to compare the pragmatic, short-term psychotherapy Narrative Exposure Therapy for Children (KIDNET) with treatment as usual (TAU) for the treatment of young refugees in Germany. This update outli...

DOAJ Open Access (DOAJ) DOI: 10.1186/s13063-022-06288-8

Factors influencing Diffusion of Health Technology

AJ van der Watt, MW Pretorius, Leon Pretorius • INCOSE International Symposium (2014)

Abstract Health Technology is at the core of delivering quality healthcare service in many environments. To this end, the adoption of innovation plays an important role in ensuring the most current solutions are consistently applied in diag...

OPENALEX DOI: https://doi.org/10.1002/j.2334-5837.2014.00039.x

Treatment of Gluteal Tendinopathy: A Systematic Review and Stage-Adjusted Treatment Recommendation

Andreas Ladurner MD, Jane Fitzpatrick PhD, MBBS, John M. O’Donnell MBBS • Orthopaedic Journal of Sports Medicine (2021)

Background: Gluteal tendinopathy is the most common lower limb tendinopathy. It presents with varying severity but may cause debilitating lateral hip pain. Purpose: To review the therapeutic options for different stages of gluteal tendinopa...

DOAJ Open Access (DOAJ) DOI: 10.1177/23259671211016850

Skilled antenatal care services utilisation in sub-Saharan Africa: a pooled analysis of demographic and health surveys from 32 countries

Kwamena Sekyi Dickson, Joshua Okyere, Bright Opoku Ahinkorah, Abdul-Aziz Seidu et al. • BMC Pregnancy and Childbirth (2022)

Abstract Background Each day, an estimated 800 women die from preventable pregnancy and childbirth related complications, where 99% of these avoidable deaths happen in low-and middle-income countries. Skilled attendance during antenatal car...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12884-022-05137-5

Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran

Negar Morovatdar, Shapour Badiee Aval, Seyed Mohammad Reza Hosseini Yazdi, Farzaneh Norouzi et al. • Iranian Journal of Neonatology (2015)

Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran Background: Phenylketonuria is an autosomal recessive disease. Early diagnosis is a important public health intervention to prevent neurol...

DOAJ Open Access (DOAJ)

Non-metallic iodine single-atom catalysts with optimized electronic structures for efficient Fenton-like reactions

Junjun Pei, Jianbin Liu, Kaixing Fu, Yukui Fu et al. • Nature Communications (2025)

Abstract In this study, we introduce a highly effective non-metallic iodine single-atom catalyst (SAC), referred to as I-NC, which is strategically confined within a nitrogen-doped carbon (NC) scaffold. This configuration features a distinc...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41467-025-56246-6

Coffee Silverskin Phytocompounds as a Novel Anti-Aging Functional Food: A Pharmacoinformatic Approach Combined with In Vitro Study

Clarin Hayes, Fahrul Nurkolis, Dewa Ayu Agus Sri Laksemi, Sanghyun Chung et al. • Molecules (2023)

Coffee became a beverage that was in demand in the world and consequently produced millions of tons of coffee byproducts namely coffee silverskin (CS). Unutilized CS will be waste and cause environmental pollution such as greenhouse gas emi...

DOAJ Open Access (DOAJ) DOI: 10.3390/molecules28207037

Early disc degeneration in radiotherapy-treated childhood brain tumor survivors

Petra Grahn, Tiina Remes, Reetta Kivisaari, Maria H. Suo-Palosaari et al. • BMC Musculoskeletal Disorders (2023)

Abstract Background Childhood brain tumor (BT) survivors have an increased risk of treatment-related late effects, which can reduce health-related quality of life and increase morbidity. This study aimed to investigate lumbar disc degenerat...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12891-023-06509-4

Rap GTPase Interactor: A Potential Marker for Cancer Prognosis Following Kidney Transplantation

Qiang Fu, Qiang Fu, Qiang Fu, Fan Yang et al. • Frontiers in Oncology (2019)

Post-transplant (post-Tx) kidney cancer has become the second-highest cause of death in kidney recipients. Late diagnosis and treatment are the main reasons for high mortality. Further research into early diagnosis and potential treatment i...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2019.00737

Health Technology Assessment

Lise Lund Håheim, Berit Mørland • IGI Global eBooks (2009)

Scientific publications in medical fields are rapidly increasing and are overwhelming in numbers. This poses a challenge to health authorities, and health professionals who need knowledge to make informed decisions in finding the best evide...

OPENALEX DOI: https://doi.org/10.4018/978-1-60566-356-2.ch046

The evolution of digital health technologies in cardiovascular disease research

Clara C. Zwack, Milad Haghani, Matthew Hollings, Ling Zhang et al. • npj Digital Medicine (2023)

When implemented in practice, digital technologies have shown improvements in morbidity and mortality outcomes in patients with cardiovascular disease (CVD). For scholars, research into digital technologies in cardiovascular care has been r...

OPENALEX cc-by DOI: https://doi.org/10.1038/s41746-022-00734-2 PMC: 9808768