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The evaluation of changes in muscle strength in elderly patients with premature aging

Tatyana V. Pavlova, Kirill I. Proshchayev, Elmira E. Satarinova, Natalia B. Pilkevich et al. • Медицинский вестник Юга России (2019)

Purpose: to evaluate changes in muscle strength in elderly patients with signs of premature aging. Materials and methods: the study included 1080 people: 540 aged 44 to 54 years (mean age 49.1±2.2) and 540 at the age of 55 to 64 years (mean...

DOAJ Open Access (DOAJ) DOI: 10.21886/2219-8075-2019-10-1-59-64

Alpha-Band EEG Modulation as a Potential Aged-Related Biomarker for Biofeedback-Driven Motor–Cognitive Adaptability

Swapno Aditya, Adam Clarke, Lucy Armitage, Wing-Kai Lam et al. • Sensors (2026)

Background: Age-related changes in motor–cognitive function are associated with altered neural adaptability, particularly during tasks requiring integration of cognitive and motor processes. Dual-task paradigms are commonly used to assess s...

DOAJ Open Access (DOAJ) DOI: 10.3390/s26144575

Why did an effective Dutch complex psycho-social intervention for people with dementia not work in the German healthcare context? Lessons learnt from a process evaluation alongside a multicentre RCT

Sebastian Voigt-Radloff, Maud Graff, Myrra Vernooij-Dassen, Rainer Leonhart et al. • BMJ Open (2011)

Background The positive effects of the Dutch Community Occupational Therapy in Dementia programme on patients' daily functioning were not found in a multicentre randomised controlled trial (RCT) in Germany.Objectives To evaluate possible ef...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjopen-2011-000094

Changes in daily living dependency and incident depressive symptoms among older individuals: findings from four prospective cohort studies

Hongwei Liu, Juxiang Yang, Gang Song, Minheng Zhang et al. • BMJ Mental Health (2025)

Background With rapid population ageing, depressive symptoms in older adults have become a pressing public health concern. While functional dependency is a known risk factor, the impact of changes in dependency over time remains unclear.Obj...

DOAJ Open Access (DOAJ) DOI: 10.1136/bmjment-2025-301749

Risk Profiles for Falls among Older Adults: New Directions for Prevention

William A. Satariano, Constance Wang, Melissa E. Kealey, Elaine Kurtovich et al. • Frontiers in Public Health (2017)

ObjectiveTo address whether neighborhood factors, together with older adults’ levels of health and functioning, suggest new combinations of risk factors for falls and new directions for prevention. To explore the utility of Grade-of-Members...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpubh.2017.00142

Social Support, Social Participation, and Life Accomplishment of Older Adult Residents of Assisted Living Facilities and Their Adjoining Communities

Christopher Olusanjo Akosile PhD, Chisom Onyekwuluje BMR, Ukamaka Gloria Mgbeojedo PhD, Emmanuel Chiebuka Okoye PhD et al. • Gerontology and Geriatric Medicine (2023)

Objectives: To assess and compare levels of social support (SS), social participation (SP) and life accomplishment (LA) among older adults in some assisted-living facilities (ALFs) and their community-dwelling (CD) peers. Methods: One hundr...

DOAJ Open Access (DOAJ) DOI: 10.1177/23337214231218797

Dietary antioxidants and lifespan: Relevance of environmental conditions, diet, and genotype of experimental models

Alfonso Varela-López, José M. Romero-Márquez, María D. Navarro-Hortal, César L. Ramirez-Tortosa et al. • Experimental Gerontology (2023)

The rise of life expectancy in current societies is not accompanied, to date, by a similar increase in healthspan, which represents a great socio-economic problem. It has been suggested that aging can be manipulated and then, the onset of a...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2023.112221

Epigenetic Age Acceleration and Hearing: Observations From the Baltimore Longitudinal Study of Aging

Pei-Lun Kuo, Ann Zenobia Moore, Frank R. Lin, Frank R. Lin et al. • Frontiers in Aging Neuroscience (2021)

Objectives: Age-related hearing loss (ARHL) is highly prevalent among older adults, but the potential mechanisms and predictive markers for ARHL are lacking. Epigenetic age acceleration has been shown to be predictive of many age-associated...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnagi.2021.790926

Constructing the concept of healthy ageing and examining its association with loneliness in older adults

Ivy Yan Zhao, Mu-Hsing Ho, Stefanos Tyrovolas, Sasha Yuanjie Deng et al. • BMC Geriatrics (2023)

Abstract Background World Health Organization (WHO) has defined healthy ageing by highlighting five functional ability domains to (meet basic needs, make decisions, be mobile, build and maintain relationships, and contribute to society), wh...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-04019-5

Association of negative opinions towards telepsychiatry with its prior use and the level of geriatric psychiatry care among nursing home stakeholders

S Pirbay, MD, S Abou Kassm, MD, MPH, C Di-Maggio, MD, F Naudet, MD, PhD et al. • Archives of Gerontology and Geriatrics Plus (2025)

Objectives: Despite the benefits of geriatric telepsychiatry, the lack of support from the staff remains one of the major challenges it faces. We wanted to explore whether negative opinions towards telepsychiatry in nursing home (NH) stakeh...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2025.100150

Aging, aerobic exercise, and cardiovascular health: Barriers, alternative strategies and future directions

Kevin O. Murray, Sophia A. Mahoney, Ravinandan Venkatasubramanian, Douglas R. Seals et al. • Experimental Gerontology (2023)

Age-associated cardiovascular (CV) dysfunction, namely arterial dysfunction, is a key antecedent to the development of CV disease (CVD). Arterial dysfunction with aging is characterized by impaired vascular endothelial function and stiffeni...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2023.112105

Association of triglyceride glucose-body roundness index and body roundness index with incident sarcopenia among Chinese older adults: A nationwide cohort study

Yu -Yang Ma, Hai-Yan Li, Ruo-Nan Yao, Gong Cheng et al. • Experimental Gerontology (2025)

Background: The relationship between TyG-BRI, BRI, and the sarcopenia definition proposed by the Asian Working Group for Sarcopenia (AWGS) in 2019 remains unclear. This research focused on exploring the relationship between the TyG-BRI inde...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.exger.2025.112946

PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway

Liwei Wu, Qiang Yu, Ping Cheng, Chuanyong Guo • PPAR Research (2021)

Background. Hepatic ischemia-reperfusion (IR) injury is one of the severe complications associated with liver surgery and leads to liver dysfunction. PPARγ is always linked with various physiologic pathways, and it can alleviate liver damag...

DOAJ Open Access (DOAJ) DOI: 10.1155/2021/6626295

Single-cell RNA sequencing to detect age-associated genes that identify senescent cells in the liver of aged mice

Yuta Doshida, Shinichi Hashimoto, Sadahiro Iwabuchi, Yuka Takino et al. • Scientific Reports (2023)

Abstract Senescent cells are predicted to occur and increase in animal tissues with aging. However, senescent cells in the tissues of aged animals remain to be identified. We refer to the marker genes to identify senescent cells in tissues ...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-023-41352-6

Bone turnover markers and parameters of functional and structural state in patients with chronic spinal cord injuries in 5 years and later after the trauma

M.A. Bystrytska, V.V. Povoroznyuk • Bolʹ, Sustavy, Pozvonočnik (2017)

Актуальность. Увеличение продолжительности жизни пациентов с травмой позвоночника и спинного мозга (ТПСМ) привлекло внимание к поздним осложнениям ТПСМ, в частности к остеопорозу. Цель исследования — оценить структурно-функциональное состоя...

DOAJ Open Access (DOAJ) DOI: 10.22141/2224-1507.7.2.2017.108700

Effective analysis of neurotoxicity and mechanisms of dioctyl terephthalate using network toxicology

Hao Tang, Ting Qin, Zhiwen Yan, Changqing Li et al. • Frontiers in Neuroscience (2026)

ObjectiveDioctyl terephthalate (DOTP), a widely used plasticizer in food packaging and environmental materials, has raised concerns regarding its potential impact on human health. This study aims to investigate the neurotoxicity-related mec...

DOAJ Open Access (DOAJ) DOI: 10.3389/fnins.2026.1783807

Using Wearable Devices to Examine the Associations of Sedentary Behavior with Perceived and Performance Fatigability Among Older Adults: The Study of Muscle, Mobility and Aging (SOMMA)

Reagan E. Garcia, Anne B. Newman, Eileen Johnson, Yujia Susanna Qiao et al. • Sensors (2025)

Fatigability, a phenotype of poor energy regulation, is associated with lower physical activity in older adults, but independent associations with sedentary behavior are unknown. We examined whether sedentary behavior was associated with fa...

DOAJ Open Access (DOAJ) DOI: 10.3390/s25092722

Local, collaborative, stepped, and personalized care management for older people with chronic diseases – results from the randomized controlled LoChro-trial

Gloria Metzner, Lukas Maximilian Horstmeier, Jürgen Bengel, Eva Maria Bitzer et al. • BMC Geriatrics (2023)

Abstract Background In the aging population of Western societies, an increasing number of older adults have multiple chronic diseases. As multifaceted health problems imply the involvement of several healthcare professionals, multimorbid ol...

DOAJ Open Access (DOAJ) DOI: 10.1186/s12877-023-03797-2

The burden and determinants of cognitive impairment among individuals with chronic diseases in Ethiopia: A systematic review and meta-analysis

Addisu Getie, Melaku Bimerew, Mihretie Gedfew, Baye Tsegaye Amlak et al. • Archives of Gerontology and Geriatrics Plus (2025)

Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.aggp.2025.100171