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Academic Articles & Research Papers
Showing 20 of 877 academic articles
Matthew Lynch, Sophie Manoy, Peter D. Sly, Claire E. Wainwright et al. • EBioMedicine
(2025)
Summary: Background: Ataxia-telangiectasia (A-T) is a rare multisystem disease characterised by neurodegenerative cerebellar ataxia, lung disease, immune deficiency, high cancer risk, and mitochondrial dysfunction. A-T cells demonstrate de...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.ebiom.2025.105840
Yang Fei, Hui Xu, Chunwei Zhang, Jingjing Wang et al. • Beilstein Journal of Nanotechnology
(2025)
Esophageal cancer (EC) is a common malignant tumor of the digestive tract with poor prognosis and high mortality. The early diagnosis of EC mainly depends on endoscopic diagnosis, which not only needs to bear certain economic pressure, but ...
DOAJ
Open Access (DOAJ)
DOI: 10.3762/bjnano.16.121
Tahany Saleh Aldayel, Mohamed M. Badran, Abdullah H. Alomrani, Nora A. AlFaris et al. • Heliyon
(2023)
Aloe perryi (AP) has gained considerable interest as a medicinal herb in various biological applications due to its rich phytochemical composition. However, the therapeutic benefits of AP could be potentiated by utilizing nanotechnology. Mo...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.heliyon.2023.e22691
Fatma H. El-Didi, Marwa M. Essawy, Sagy L. Asar, Sahar M. El-Sheikh et al. • Alexandria Dental Journal
(2019)
INTRODUCTION: Oral squamous cell carcinoma (OSCC) is the sixth most common cancer worldwide with high mortality rate. Conventional treatment strategies have improved but remain far from optimal. Cancer research is focused on improving cance...
DOAJ
Open Access (DOAJ)
DOI: 10.21608/adjalexu.2019.57569
Claudio Tomi-Andrino, Alina Pandele, Klaus Winzer, John King et al. • Scientific Reports
(2022)
Abstract The manifestation of intra- and inter-tumor heterogeneity hinders the development of ubiquitous cancer treatments, thus requiring a tailored therapy for each cancer type. Specifically, the reprogramming of cellular metabolism has b...
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Open Access (DOAJ)
DOI: 10.1038/s41598-022-14721-w
Heabin Kim, Hyun-Taek Kim, Seung-Hyun Jung, Jong Won Han et al. • Marine Drugs
(2023)
The discovery of new highly effective anticancer drugs with few side effects is a challenge for drug development research. Natural or synthetic anticancer peptides (ACPs) represent a new generation of anticancer agents with high selectivity...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/md21120607
Xuanzhao Chen, Zeyan Li, Meihua Liang, Ziyang Zhang et al. • World Journal of Surgical Oncology
(2023)
Abstract Background Triple-negative breast cancer (TNBC) is the most heterogenous and aggressive subtype of breast cancer. Chemotherapy remains the standard treatment option for patients with TNBC owing to the unavailability of acceptable t...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12957-023-03078-7
Youfeng Shen, Kaixiang Xu, Zaimei Yuan, Jianxiong Guo et al. • Journal of Translational Medicine
(2017)
Abstract Background Pigs have many features that make them attractive as biomedical models for various diseases, including cancer. P53 is an important tumor suppressor gene that exerts a central role in protecting cells from oncogenic trans...
DOAJ
Open Access (DOAJ)
DOI: 10.1186/s12967-017-1327-0
Alicia Hüls • Current Objectives of Postgraduate American Studies
(2025)
This paper examines Audre Lorde’s The Cancer Journals (2020) and her journey post-mastectomy, in relation to José Muñoz’s theory of disidentification, which he discusses in his book Disidentifications: Queers of Color and the Performance of...
DOAJ
Open Access (DOAJ)
DOI: 10.5283/copas.390
Tara Alaadin Abdulrazzaq, Jangi Shawakat Salayi • Advanced Medical Journal
(2023)
Background & Objectives: Colorectal cancer is the commonest malignancy in the gastrointestinal tract third and the second leading cause of cancer death worldwide. The advanced stages and poor tumor grade of colorectal cancer are likely to b...
DOAJ
Open Access (DOAJ)
DOI: 10.56056/amj.2023.202
Lilla Bűdi, Dániel Hammer, Rita Varga, Veronika Müller et al. • Pathology and Oncology Research
(2025)
ObjectivesSpingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circ...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/pore.2024.1611929
Valerio Nardone, Federica Marmorino, Marco Maria Germani, Natalia Cichowska-Cwalińska et al. • Current Oncology
(2024)
The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in per...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/curroncol31090369
Addisu Getie, Melaku Bimerew, Mihretie Gedfew, Baye Tsegaye Amlak et al. • Archives of Gerontology and Geriatrics Plus
(2025)
Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects indi...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.aggp.2025.100171
Graciela Gavia-García, David Hernández-Álvarez, Taide Laurita Arista-Ugalde, Itzen Aguiñiga-Sánchez et al. • Molecules
(2026)
Consumption of Sechium edule var. nigrum spinosum has antioxidant and hypoglycemic effects. Regarding the former, certain signaling pathways that influence these effects have already been proposed; however, the underlying molecular mechanis...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules31071182
Laurenz De Cock, Erika D’haenens, Lies Vantomme, Lynn Backers et al. • npj Genomic Medicine
(2025)
Abstract RNA sequencing (RNA-seq) has become key to complementing exome and genome sequencing for variant interpretation. We present a minimally invasive RNA-seq protocol using short-term cultured peripheral blood mononuclear cells (PBMCs) ...
DOAJ
Open Access (DOAJ)
DOI: 10.1038/s41525-025-00502-7
Christian G. Ziegler, Carina Riediger, Matthias Gruber, Carola Kunath et al. • Frontiers in Endocrinology
(2022)
Pheochromocytomas (PCCs) are rare but potentially lethal tumors that arise from the adrenal medulla. The clinical suspicion and diagnosis of PCC can be challenging due to the non-specific nature of signs and symptoms. In many patients, infe...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fendo.2022.967995
Shiro Okumura, Hironori Koga, Kuniyo Inouye, Eiichi Mizuki • Toxins
(2014)
Parasporin-4 (PS4) is an aerolysin-type β-pore-forming toxin produced by Bacillus thuringiensis strain A1470. It exhibits specific cytotoxicity against human cancer cell lines; therefore, it is expected to be useful for the diagnosis and tr...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/toxins6072115
Hammad Ullah, Yaseen Hussain, Cristina Santarcangelo, Alessandra Baldi et al. • Molecules
(2022)
Food spoilage makes foods undesirable and unacceptable for human use. The preservation of food is essential for human survival, and different techniques were initially used to limit the growth of spoiling microbes, e.g., drying, heating, sa...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/molecules27061906
Thao Nguyen, Toshiaki Yoshikawa, Yusuke Ito, Hitomi Kasuya et al. • STAR Protocols
(2024)
Summary: Chimeric antigen receptor (CAR) T cell therapy often causes serious toxicities, such as cytokine release syndrome (CRS), mainly due to interleukin-6 (IL-6) secreted by monocyte lineage cells. Here, we describe a protocol to generat...
DOAJ
Open Access (DOAJ)
DOI: 10.1016/j.xpro.2024.103423
Lynette Mackenzie, Amanda M. Clifford, Eleanor Fallon, Joanna M. Allardyce • BMJ Open
(2026)
Introduction Falls are a significant health concern and associated with cancer survivorship. Falls can result in negative psychosocial consequences for cancer survivors and economic sequelae for healthcare delivery. There are cancer-specifi...
DOAJ
Open Access (DOAJ)
DOI: 10.1136/bmjopen-2025-110212