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Academic Articles & Research Papers
Showing 20 of 1,383 academic articles
Yi-Lei Zhang, Ruo-Chen Wang, Ken Cheng, Brian Z. Ring et al. • Cancer Biology & Medicine
(2017)
Ras-associated protein-1 (Rap1), a small GTPase in the Ras-related protein family, is an important regulator of basic cellular functions (e.g., formation and control of cell adhesions and junctions), cellular migration, and polarization. Th...
DOAJ
Open Access (DOAJ)
DOI: 10.20892/j.issn.2095-3941.2016.0086
Augusto Berrocal, Nicholas C Lammers, Hernan G Garcia, Michael B Eisen • eLife
(2020)
We used live imaging to visualize the transcriptional dynamics of the Drosophila melanogaster even-skipped gene at single-cell and high-temporal resolution as its seven stripe expression pattern forms, and developed tools to characterize an...
DOAJ
Open Access (DOAJ)
DOI: 10.7554/eLife.61635
Saul Vislei Simões da Silva, Orlando Maia Barboza, Jéssica Teles Souza, Érica Novaes Soares et al. • Molecules
(2021)
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water, extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological use. The aim of this study was to perform structural mod...
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Open Access (DOAJ)
DOI: 10.3390/molecules26226923
Li Rong, Haiyu Li, Zhaodong Li, Jing Ouyang et al. • Frontiers in Medicine
(2020)
Background and Objective: Chemotherapy and radiotherapy are effective treatment options for cervical cancer (CC), but their efficacy is limited by short survival rate of about 5 years particularly for advance stage CC. Bioinformatics analys...
DOAJ
Open Access (DOAJ)
DOI: 10.3389/fmed.2020.608441
Shih-Ho Wang, Chin-Hu Wu, Chin-Chuan Tsai, Tai-Yu Chen et al. • Current Issues in Molecular Biology
(2022)
Taraxacum officinale (dandelion) is often used in traditional Chinese medicine for the treatment of cancer; however, the downstream regulatory genes and signaling pathways mediating its effects on breast cancer remain unclear. The present s...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/cimb44050142
Cheng J, Huang Y • Journal of Inflammation Research
(2026)
Jian Cheng, Yangfeng Huang Department of Traditional Chinese Medicine, Sichuan Provincial People’s Hospital, School of Medicine,University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of ChinaCorrespond...
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Open Access (DOAJ)
Wentong Chen, Mengxiao Ge, Shuangyi Sun, Hanxiao Zhang et al. • Scientific Reports
(2025)
Abstract As critical precursors to colorectal cancer (CRC), high-risk colorectal adenomas (HR-CRAs) lack effective chemopreventive strategies beyond endoscopic resection. We previously established a standardized protocol for culturing patie...
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Open Access (DOAJ)
DOI: 10.1038/s41598-025-32406-y
Weiwei Liu, Yan Wang, Zhimei Qiu, Ranzun Zhao et al. • PeerJ
(2020)
Background The occurrence of pathological cardiac fibrosis is attributed to tissue hypoxia. Circular RNAs play significant regulatory roles in multiple cardiovascular diseases and are involved in the regulation of physiological and pathophy...
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Open Access (DOAJ)
DOI: 10.7717/peerj.9796
Chao Ren, Peiyuan Yin, Neng Ren, Zhe Wang et al. • Stem Cell Research & Therapy
(2018)
Abstract Recent studies have suggested that the regulation of endogenous neural stem cells (NSCs) or transplanting of exogenous nerve cells are the newest and most promising methods for the treatment of dementia and other neurological disea...
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Open Access (DOAJ)
DOI: 10.1186/s13287-018-0807-3
Keisuke Hitachi, Masahiko Honda, Kunihiro Tsuchida • Cells
(2022)
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condit...
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Open Access (DOAJ)
DOI: 10.3390/cells11152291
Deyu Jiang, Miao Luo, Changxi Liu, Yashuo Zhang et al. • Virtual and Physical Prototyping
(2025)
In this study, a Ti1.5Nb1Ta0.5Zr1Mo0.5 (TNTZM) high-entropy alloy was fabricated using laser powder bed fusion (LPBF). By integrating 63 sets of parameter trials with machine learning (ML) models, an optimised process window was identified,...
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Open Access (DOAJ)
DOI: 10.1080/17452759.2025.2524524
Lucian Munteanu, Ana Boldureanu, George-Dan Hânceanu, Vasile Ursachi • Arheologia Moldovei
(2022)
The medieval necropolis of Brad overlaps the fortified section of the Geto-Dacian fortress of Zargidava, located on the left bank of the Siret River. Altogether, 962 graves were researched here during the years 1963-2004. The numismatic mat...
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Open Access (DOAJ)
DOI: 10.11588/amold.2019.1.92555
Joan-Carles MÈLICH • Teoría de la Educación: Revista Interuniversitaria
(2009)
RESUMEN: Tomando como telón de fondo la noción de «excentricidad» de Helmuth Plessner se presentan en este artículo las líneas generales de una antropología narrativa. Según ésta, los seres humanos, además de naturaleza biológica y cultural...
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Open Access (DOAJ)
DOI: 10.14201/teri.986
Tiancheng Yang, Xiuhua Si, Jinxiang Xi • Life
(2024)
The human tongue has highly variable morphology. Its role in regulating respiratory flows and deposition of inhaled aerosols remains unclear. The objective of this study was to quantify the uncertainty of nanoparticle deposition from the va...
DOAJ
Open Access (DOAJ)
DOI: 10.3390/life14030406
Hiroki Senshu, Takahide Mizuno, Toru Nakura, Ryo Suetsugu et al. • Progress in Earth and Planetary Science
(2025)
Abstract The spacecraft for the Japanese Martian Moon eXploration mission is equipped with a LIDAR laser altimeter. The slant range continuously measured by the LIDAR is used for the correction of the local topography and the orbit and atti...
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Open Access (DOAJ)
DOI: 10.1186/s40645-025-00705-7
Han Xiao, Han Xiao, Xiaoqian Zhang, Xiaoqian Zhang et al. • Frontiers in Environmental Science
(2022)
Forest disturbance monitoring can provide scientific data for the decision making and management of nature reserves. LandTrendr algorithm has been applied to identify forest disturbances on a long-time scale through appropriate segmentation...
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Open Access (DOAJ)
DOI: 10.3389/fenvs.2022.891752
LIU Jianxing, ZHANG Ouyang, MA Xiaolong, CHEN Meng et al. • Nanjing Hangkong Hangtian Daxue Xuebao
(2026)
Free-floating space robots （FFSRs） have emerged as critical unmanned platforms for long-term in-orbit services thanks to their high mobility and extended operational lifespan. However， external disturbances caused by dynamic space environme...
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Open Access (DOAJ)
DOI: 10.16356/j.2097-6771.2026.01.015
Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li et al. • Molecular Cancer
(2021)
Abstract N6-Methyladenosine (m6A) is an RNA modification that interacts with numerous coding and non-coding RNAs and plays important roles in the development of cancers. Nonetheless, the clinical impacts of m6A interactive genes on these ca...
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Open Access (DOAJ)
DOI: 10.1186/s12943-021-01362-2
Sylvester Sebola, Niladri Chakraborty, Morné Rowan Sjölander • Mathematics
(2026)
This paper proposes a combined maximal precedence–exceedance test (MPErs) that integrates maximal precedence and maximal exceedance statistics tests to provide sensitivity to both early and late distributional differences between two sample...
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Open Access (DOAJ)
DOI: 10.3390/math14203658
Jennifer Belt Antwi, Nana Kena Frempong • Mathematics in Medical and Life Sciences
(2026)
Background: The classic Wells–Riley model (CWRM) is a well-established framework for estimating airborne infection risk in shared indoor environments. This study extends the framework to simultaneously incorporate fecal–oral transmission, a...
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Open Access (DOAJ)
DOI: 10.1080/29937574.2026.2714847