Academic Articles & Research Papers

Supporting the spread of health technology in community services

Health technology has been proposed as a route to financial savings and improved patient safety for many years within the NHS. Nurses have a key role to play in transforming care through such technology but, despite high-level endorsement, ...

Toward trustworthy COVID-19 interventions: Building vaccine trust through community-university partnerships.

Prior research identifies trust as critical to increase vaccine acceptance and uptake. However, few intervention studies have sought to develop or test strategies for bolstering vaccine-related trust. To address this gap, this exploratory s...

Everyday Health: Technology for Adaptive Aging

Coffee Silverskin Phytocompounds as a Novel Anti-Aging Functional Food: A Pharmacoinformatic Approach Combined with In Vitro Study

Coffee became a beverage that was in demand in the world and consequently produced millions of tons of coffee byproducts namely coffee silverskin (CS). Unutilized CS will be waste and cause environmental pollution such as greenhouse gas emi...

Early disc degeneration in radiotherapy-treated childhood brain tumor survivors

Abstract Background Childhood brain tumor (BT) survivors have an increased risk of treatment-related late effects, which can reduce health-related quality of life and increase morbidity. This study aimed to investigate lumbar disc degenerat...

Positron emission tomography: establishing priorities for health technology assessment.

BACKGROUND: Positron emission tomography (PET) is an expensive diagnostic imaging technology. Despite the long history of PET development, the costs and effectiveness of its use in routine clinical practice remain unknown. Against this back...

Health Technologies as a Cost-Driver in Canada

This report describes our estimation of the effects of technological change (TC) on health care (HC) expenditures in Canada during the period 1996-2008. We focus on the effect of TC on overall nominal expenditures, as well as the effects of...

Formation and Analysis of Volatile and Odor Compounds in Meat—A Review

The volatile composition and odor of meat and meat products is based on the precursors present in the raw meat. These are influenced by various pre-slaughter factors (species, breed, sex, age, feed, muscle type). Furthermore, post-mortem co...

The influence of frailty syndrome on medication adherence among elderly patients with hypertension

Beata Jankowska-Polańska,1 Krzysztof Dudek,2 Anna Szymanska-Chabowska,3 Izabella Uchmanowicz1 1Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 2Department of Logistic and Transport Systems, Faculty of ...

Preoperative and intraoperative assessment of myometrial invasion in patients with FIGO stage I non-endometrioid endometrial carcinoma—a large-scale, multi-center, and retrospective study

Abstract Introduction Myometrial invasion is a prognostic factor for lymph node metastases and decreased survival in non-endometrioid endometrial carcinoma patients. Herein, we explored the mode of myometrial invasion diagnosis in FIGO stag...

The Ethical Use of Mobile Health Technology in Clinical Psychiatry

The rapid rise of mobile health technologies, such as smartphone apps and wearable sensors, presents psychiatry with new tools of potential value in caring for patients. Novel diagnostic and therapeutic applications of these technologies ha...

Expression of Renal Vitamin D and Phosphatonin-Related Genes in a Sheep Model of Osteoporosis

Osteoporosis is a significant public health issue around the world, with post-menopausal osteoporosis due to estrogen deficiency resulting in approximately ¾ of cases. In this study, 18 aged Merino ewes were ovariectomized, and 10 were cont...

A Single Simulated Heliox Dive Modifies Endothelial Function in the Vascular Wall of ApoE Knockout Male Rats More Than Females

IntroductionThe number of divers is rising every year, including an increasing number of aging persons with impaired endothelial function and concomitant atherosclerosis. While diving is an independent modulator of endothelial function, lit...

Alleviating D-Galactose-Induced Aging in Mice by Modulating Gut-Liver Axis Using <i>Lactiplantibacillus plantarum</i> TY-Y10

Oxidative stress is closely linked to aging. Probiotics, whether viable or heat-inactivated, have shown antioxidant properties; however, their effect and mechanism of action in reducing oxidative stress during aging remains underexplored. T...

Muscle Bmal1 is Dispensable for the Progress of Neurogenic Muscle Atrophy in Mice

Global deletion of aryl hydrocarbon receptor nuclear translocator-like ('Arntl'; also known as 'Bmal1'), a molecular component of the circadian clock, resulted in an extreme loss of muscle mass. However, the functional role of muscle BMAL1 ...

LADS: a powerful vaccine platform for cancer immunotherapy and prevention

Abstract Background The intracellular bacterium Listeria monocytogenes is an attractive vector for cancer immunotherapy as it can effectively deliver tumor antigens to antigen-presenting cells, leading to a robust antitumor response. Result...

Computable phenotype for real-world, data-driven retrospective identification of relapse in ANCA-associated vasculitis

Objective ANCA-associated vasculitis (AAV) is a relapsing-remitting disease, resulting in incremental tissue injury. The gold-standard relapse definition (Birmingham Vasculitis Activity Score, BVAS&gt;0) is often missing or inaccurate in re...

Digital health technology in clinical trials

Digital health technologies (DHTs) have brought several significant improvements to clinical trials, enabling real-world data collection outside of the traditional clinical context and more patient-centered approaches. DHTs, such as wearabl...

Mapping the acute trajectory of sport-related concussion outcomes across symptoms, cognition, and blood biomarkers

Sport-related concussion (SRC) and its potential neurological sequela represent an emerging global health concern, requiring improved recovery management and strategies for return-to-play (RTP) to enhance brain health in athletes. Given the...

Change in lifestyle with health technology

To preserve excellent health and prevent chronic diseases, one must adopt a healthy lifestyle. Yet, altering one's way of life can be difficult, particularly without the necessary resources and assistance. Luckily, new opportunities to enco...