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Patient and allograft outcomes after kidney transplant for the Indigenous patients in the United States.

Regan Seipp, Nan Zhang, Sumi Sukumaran Nair, Hasan Khamash et al. • PLoS ONE (2021)

BackgroundThe objective is to assess cardiovascular (CV), malignancy, infectious, graft outcomes and tacrolimus levels for the Indigenous patients compared to Whites after kidney transplant (KTx).Methods165 Indigenous and 165 White patients...

DOAJ Open Access (DOAJ) DOI: 10.1371/journal.pone.0244492

Phosphopeptide binding to the N-SH2 domain of tyrosine phosphatase SHP2 correlates with the unzipping of its central β-sheet

Michelangelo Marasco, John Kirkpatrick, Teresa Carlomagno, Jochen S. Hub et al. • Computational and Structural Biotechnology Journal (2024)

SHP2 is a tyrosine phosphatase that plays a regulatory role in multiple intracellular signaling cascades and is known to be oncogenic in certain contexts. In the absence of effectors, SHP2 adopts an autoinhibited conformation with its N-SH2...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.csbj.2024.02.023

Program-Based Lung Cancer Care: A Prospective Observational Tumor Registry Linkage Study

Wei Liao, PhD, Meredith Ray, PhD, Carrie Fehnel, BBA, Jordan Goss, MA et al. • JTO Clinical and Research Reports (2024)

Introduction: Low-dose computed tomography screening (LDCT) and lung nodule programs (LNP) promote early lung cancer detection, improve survival; Multidisciplinary Care Programs (MDC) promote guideline-concordant care. The impact of such pr...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.jtocrr.2023.100629

Endoscopic Follow-Up of Positive Fecal Occult Blood Testing in the Ontario FOBT Project

Lawrence Paszat, Linda Rabeneck, Lori Kiefer, Verna Mai et al. • Canadian Journal of Gastroenterology (2007)

BACKGROUND: The Ontario FOBT Project is a pilot study of fecal occult blood testing (FOBT) for colorectal cancer screening conducted among age-eligible volunteers (50 to 75 years) in 12 of 37 public health regions in Ontario....

DOAJ Open Access (DOAJ) DOI: 10.1155/2007/569689

Study of mutations in IDH1 and IDH2 genes in a sample of gliomas from Colombian population

Orlando Ricaurte, Karina Neita, Danyela Valero, Jenny Ortega-Rojas et al. • Biomédica: revista del Instituto Nacional de Salud (2018)

Introduction: Gliomas are the most common primary tumors of the central nervous system and, according to their malignancy, they are graded from I to IV. Recent studies have found that there is an association between gliomas and mutations in...

DOAJ Open Access (DOAJ) DOI: 10.7705/biomedica.v38i0.3708

Circulating tumour cell enumeration, biomarker analyses, and kinetics in patients with colorectal cancer and other GI malignancies

Walla Malkawi, Areeb Lutfi, Maaz Khan Afghan, Lamisha Mashiyat Shah et al. • Frontiers in Oncology (2023)

ObjectiveMost of the work in terms of liquid biopsies in patients with solid tumors is focused on circulating tumor DNA (ctDNA). Our aim was to evaluate the feasibility of using circulating tumor cells (CTCs) in peripheral blood samples fro...

DOAJ Open Access (DOAJ) DOI: 10.3389/fonc.2023.1305181

Immunological and Viral Profiles of Squamous Cell Carcinoma in Transplant and Non‐Transplant Patients in Singapore

Choon Chiat Oh, Boon Yee Lim, Elizabeth Chun Yong Lee, Bavani Kannan et al. • JEADV Clinical Practice (2025)

ABSTRACT Background Cutaneous squamous cell carcinoma (cSCC) remains poorly understood at the molecular level, both in the immunocompetent and immunosuppressed population with skin of colour. Data on the diversity of viruses found in cSCC i...

DOAJ Open Access (DOAJ) DOI: 10.1002/jvc2.70142

Fatty acid composition, bioactive phytochemicals, antioxidant properties and oxidative stability of edible fruit seed oil: effect of preharvest and processing factors

Tafadzwa Kaseke, Umezuruike Linus Opara, Olaniyi Amos Fawole • Heliyon (2020)

Fruit seed is a by-product of fruit processing into juice and other products. Despite being treated as waste, fruit seed contains oil with health benefits comparable or even higher than the conventional seed oil from field crops. In additio...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.heliyon.2020.e04962

Designed-seamless irradiation technique for extended whole mediastinal proton-beam irradiation for esophageal cancer

Okonogi Noriyuki, Hashimoto Takatuki, Ishida Masaya, Ohno Toshiki et al. • Radiation Oncology (2012)

Abstract Background Proton-beam therapy (PBT) provides therapeutic advantages over conformal x-ray therapy in sparing organs at risk when treating esophageal cancer because of the fundamental physical dose distribution of the proton-beam. H...

DOAJ Open Access (DOAJ) DOI: 10.1186/1748-717X-7-173

Curcumin Inhibits Growth of Human NCI-H292 Lung Squamous Cell Carcinoma Cells by Increasing FOXA2 Expression

Lingling Tang, Jinjin Liu, Linyun Zhu, Qingge Chen et al. • Frontiers in Pharmacology (2018)

Lung squamous cell carcinoma (LSCC) is a common histological lung cancer subtype, but unlike lung adenocarcinoma, limited therapeutic options are available for treatment. Curcumin, a natural compound, may have anticancer effects in various ...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphar.2018.00060

Efficacy, safety, and quality of life 4 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A in the phase 3 GENEr8-1 trial

Andrew D. Leavitt, Johnny Mahlangu, Priyanka Raheja, Emily Symington et al. • Research and Practice in Thrombosis and Haemostasis (2024)

Background: Valoctocogene roxaparvovec, an adeno-associated virus-mediated gene therapy for severe hemophilia A, enables endogenous factor (F)VIII expression and provides bleed protection. Objectives: Determine valoctocogene roxaparvovec du...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rpth.2024.102615

Exercise Training and Circulating Small Extracellular Vesicles: Appraisal of Methodological Approaches and Current Knowledge

Ian A. J. Darragh, Lorraine O’Driscoll, Lorraine O’Driscoll, Lorraine O’Driscoll et al. • Frontiers in Physiology (2021)

In response to acute exercise, an array of metabolites, nucleic acids, and proteins are enriched in circulation. Collectively termed “exercise factors,” these molecules represent a topical area of research given their speculated contributio...

DOAJ Open Access (DOAJ) DOI: 10.3389/fphys.2021.738333

Fumaric acid regulates morphine tolerance in bone cancer pain through spinal MrgC receptor modulation

Sijie Liu, Minghao Tang, Jing Zhao, Lulu Zhang et al. • Pakistan Journal of Pharmaceutical Sciences (2026)

Background: Bone cancer pain (BCP) represents a debilitating complication that profoundly impacts patient quality of life and predisposes to psychological comorbidities, including depression and anxiety. Objectives: To investigate the effec...

DOAJ Open Access (DOAJ) DOI: 10.36721/PJPS.2026.39.8.233.1

Psychosocial Impacts of Cancer on Siblings: Qualitative Evidence From Indonesia

Lina Dewi Anggraeni, Dessie Wanda, Happy Hayati • Jurnal Keperawatan Soedirman (2019)

Living with brothers and/or sisters who have been diagnosed with cancer can cause psychological problems on the part of siblings. This paper aimed to explore the psychosocial impacts of cancer on siblings. This research is a qualitative stu...

DOAJ Open Access (DOAJ) DOI: 10.20884/1.jks.2019.14.2.873

The effect of written emotional disclosure on health behaviors and loneliness among family caregivers of cancer patients

Malihe Izanloo, Abbas Shamsalinia, Sepide Mohammadi, Shahrbanoo Keyhanian • حیات (2025)

Background & Aim: Emotional disclosure has been associated with improvements in psychological well-being, immune function, and physical health. This study aimed to evaluate the effect of written emotional disclosure on health behaviors and ...

DOAJ Open Access (DOAJ)

Engaging Nurses in Effective Cost of Care Conversations to Address Cancer-Related Financial Toxicity: Results from an Exploratory Survey

Jean S. Edward, Amanda Thaxton Wiggins, Louis G. Baser, Haafsah Fariduddin et al. • Current Oncology (2025)

Few evidence-based trainings exist on how to equip healthcare providers, particularly nurses, with the skills to engage in cost of care conversations with patients/caregivers to mitigate the impact of cancer-related financial toxicity. This...

DOAJ Open Access (DOAJ) DOI: 10.3390/curroncol32010033

Detection of microRNA-335-5p on an Interdigitated Electrode Surface for Determination of the Severity of Abdominal Aortic Aneurysms

Bei Lu, Leiting Liu, Jingrui Wang, Yuan Chen et al. • Nanoscale Research Letters (2020)

Abstract Abdominal aortic aneurysm (AAA) refers to the enlargement of the lower artery of the abdominal aorta, and identification of an early detection tool is urgently needed for diagnosis. In the current study, an interdigitated electrode...

DOAJ Open Access (DOAJ) DOI: 10.1186/s11671-020-03331-y