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Nanomedicine for Glioblastoma: Cutting-Edge Advances and Persistent Challenges

Ladi Alik Kumar, K Sunand, Jitendra Debata, Gopal Krishna Padhy et al. • Journal of Bio-X Research (2025)

Cancer is a disorder characterized by the abnormal growth of cells that increases uncontrollably over an extended period of time. Treating cancerous brain tumors remains among the most challenging tasks for researchers, as brain tumors are ...

DOAJ Open Access (DOAJ) DOI: 10.34133/jbioxresearch.0065

Poly (acrylic acid)/tricalcium phosphate nanoparticles scaffold enriched with exosomes for cell-free therapy in bone tissue engineering: An in vivo evaluation

Nahid Moradi, Mina Soufi-Zomorrod, Simzar Hosseinzadeh, Masoud Soleimani • BioImpacts (2024)

Introduction: This study aimed to assess the potential of poly (acrylic acid)/tricalcium phosphate nanoparticles (PAA/triCaPNPs) scaffold in terms of biocompatibility and osteoconductivity properties the in-vivo evaluation as well as to inv...

DOAJ Open Access (DOAJ) DOI: 10.34172/bi.2023.27510

GROWTH AND YIELD RESPONSES OF SOYBEAN (Glycine max L.) TO ZINC OXIDE (ZnO) NANOPARTICLES FOLIAR APPLICATION

Fayomi Omotola Michael, Olasan Joseph Olalekan, Aguoru Celestine Uzoma, Terhemba Mamnenge Sarah • Biotechnologia Acta (2024)

Aim. This study was purposed to investigate the effects of zinc oxide nanoparticles (ZnO NPs) on the growth and yield performance of two soybean (Glycine max L.) varieties, TGX1904-6F and TGX1951-3F, under controlled experimental conditions...

DOAJ Open Access (DOAJ) DOI: 10.15407/biotech17.06.056

Dielectric and impedance spectroscopic studies of three phase graphene/titania/poly(vinyl alcohol) nanocomposite films

Saira Ishaq, Farah Kanwal, Shahid Atiq, Mahmoud Moussa et al. • Results in Physics (2018)

Flexible dielectric polymer composites with high dielectric permittivity and low dielectric loss have many applications in different areas of electronic industry. In this paper, we propose synthesis of flexible dielectric materials with eff...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.rinp.2018.09.049

A New Strategy for Efficient Screening and Identification of Monoclonal Antibodies against Oncogenic Avian Herpesvirus Utilizing CRISPR/Cas9-Based Gene-Editing Technology

Man Teng, Zi-Yu Zhou, Yongxiu Yao, Venugopal Nair et al. • Viruses (2022)

Marek’s disease virus (MDV) is an important oncogenic α-herpesvirus that induces Marek’s disease (MD), characterized by severe immunosuppression and rapid-onset T-cell lymphomas in its natural chicken hosts. Historically, MD is regarded as ...

DOAJ Open Access (DOAJ) DOI: 10.3390/v14092045

High‐Sensitivity Cardiac Troponin I and T Response Following Strenuous Activity is Attenuated by Smokeless Tobacco: NEEDED (North Sea Race Endurance Exercise Study) 2014

Julia Brox Skranes, Øyunn Kleiven, Kristin Moberg Aakre, Øyvind Skadberg et al. • Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (2020)

Background Use of snus, a smokeless tobacco product, is increasing in Scandinavia. Strenuous physical activity is associated with an acute increase in high‐sensitivity cardiac troponin (swhs‐cTn) concentrations. Current smoking is associate...

DOAJ Open Access (DOAJ) DOI: 10.1161/JAHA.120.017363

Decision-Making Within Forensic Psychiatric Investigations: The Use of Various Information Sources by Different Expert Groups to Reach Conclusions on Legal Insanity

Lizel Göranson, Olof Svensson, Olof Svensson, Peter Andiné et al. • Frontiers in Psychiatry (2022)

BackgroundWhich type of information experts use to make decisions regarding legal insanity within forensic psychiatric investigations (FPI) is relatively unknown, both in general and when considering variations due to case context. It is im...

DOAJ Open Access (DOAJ) DOI: 10.3389/fpsyt.2022.822519

Hypoxia-Inducible Expression of Annexin A6 Enhances the Resistance of Triple-Negative Breast Cancer Cells to EGFR and AR Antagonists

Stephen D. Williams, Tunde M. Smith, LaMonica V. Stewart, Amos M. Sakwe • Cells (2022)

Physiological changes such as hypoxia in the tumor microenvironment (TME) endow cancer cells with malignant properties, leading to tumor recurrence and rapid progression. Here, we assessed the effect of hypoxia (1% Oxygen) on the tumor supp...

DOAJ Open Access (DOAJ) DOI: 10.3390/cells11193007

Niclosamide nanoparticles enhance pancreatic cancer sensitivity to gemcitabine via HIF-1α inhibition

Susheel Kumar Nethi, Venugopal Gunda, Nagabhishek Sirpu Natesh, Brianna M. White et al. • iScience (2025)

Summary: Pancreatic cancer (PC) exhibits profound metabolic adaptations that support tumor progression, survival, and therapy resistance. Hypoxia-inducible factor-1α (HIF-1α) is a key regulator of these processes, promoting metabolic reprog...

DOAJ Open Access (DOAJ) DOI: 10.1016/j.isci.2025.114088

Piezo1 knockdown activates PI3K/AKT and enhances SPP1 to drive M2 macrophage polarization and reduce cardiac inflammation

Yunhan Zhang, Ying Zhang, Jiaoyan Song, Ziwen Zhao et al. • Scientific Reports (2026)

Abstract Piezo1 plays a key role in the immune response during sepsis. To date, our understanding of the role of Piezo1 in inflammatory diseases has mostly been limited to influencing vasomotor function and regulating inflammatory infiltrat...

DOAJ Open Access (DOAJ) DOI: 10.1038/s41598-025-34794-7